Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q03324

- LUXC1_PHOLE

UniProt

Q03324 - LUXC1_PHOLE

Protein

Acyl-CoA reductase

Gene

luxC

Organism
Photobacterium leiognathi
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

    Catalytic activityi

    A long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.

    Pathwayi

    GO - Molecular functioni

    1. acyl-CoA dehydrogenase activity Source: InterPro
    2. long-chain-fatty-acyl-CoA reductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. bioluminescence Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Luminescence

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00569.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl-CoA reductase (EC:1.2.1.50)
    Gene namesi
    Name:luxC
    OrganismiPhotobacterium leiognathi
    Taxonomic identifieri553611 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 478478Acyl-CoA reductasePRO_0000220196Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ03324.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LuxC family.Curated

    Family and domain databases

    Gene3Di3.40.605.10. 1 hit.
    InterProiIPR008670. Acyl-CoA_reduct_LuxC.
    IPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    [Graphical view]
    PfamiPF05893. LuxC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009414. LuxC. 1 hit.
    SUPFAMiSSF53720. SSF53720. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q03324-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKKIPLIIG GEVQDTSEHD VRELTLNNNT VNVPIITDKD AESITSLKIE    50
    NKLNINQIVN FLYTVGQKWK SENYSRRLTY IRDLVKFMGY SPEMAKLEAN 100
    WISMILCSKS ALYDIVENDL SSRHIVDEWL PQGDCYVKAL PKGKSIHLLA 150
    GNVPLSGVTS ILRAILTKNE CIIKTSSADP FTATALASSF IDTDANHPIT 200
    RSMSVMYWSH NEDITIPQKI MNCADVVVAW GGNDAIKWAT KHSPAHVDIL 250
    KFGPKKSISI VDNPTDIKAA AIGVAHDICF YDQQACFSTQ DIYYMGDKLD 300
    VFFDELTKQL NIYKVILPKG DQSFDEKGAF SLTERECLFA KYKVQKGEEQ 350
    AWLLTQSPAG TFGNQPLSRS AYIHHVNDIS EITPYIQNDI TQTVSITPWE 400
    ASFKYRDTLA SHGAERIIES GMNNIFRVGG AHDGMRPLQR LVKYISHERP 450
    STYTTKDVAV KIEQTRYLEE DKFLVFVP 478
    Length:478
    Mass (Da):53,858
    Last modified:June 1, 1994 - v1
    Checksum:iD730A3BE2462086B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X65156 Genomic DNA. Translation: CAA46274.1.
    PIRiJC1475.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X65156 Genomic DNA. Translation: CAA46274.1 .
    PIRi JC1475.

    3D structure databases

    ProteinModelPortali Q03324.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00569 .

    Family and domain databases

    Gene3Di 3.40.605.10. 1 hit.
    InterProi IPR008670. Acyl-CoA_reduct_LuxC.
    IPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    [Graphical view ]
    Pfami PF05893. LuxC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009414. LuxC. 1 hit.
    SUPFAMi SSF53720. SSF53720. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the luxC gene encoding fatty acid reductase of the lux operon from Photobacterium leiognathi."
      Lin J.-W., Chao Y.-F., Weng S.-F.
      Biochem. Biophys. Res. Commun. 191:314-318(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 741.

    Entry informationi

    Entry nameiLUXC1_PHOLE
    AccessioniPrimary (citable) accession number: Q03324
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3