Reviewed,
UniProtKB/Swiss-Prot Q03324 (LUXC1_PHOLE)
Last modified
November 25, 2008.
Version 41.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Acyl-CoA reductase EC=1.2.1.50 | ||
| Gene names |
| ||
| Organism | Photobacterium leiognathi | ||
| Taxonomic identifier | 658 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium |
Protein attributes
| Sequence length | 478 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. |
| Catalytic activity | A long-chain aldehyde + CoA + NADP(+) = a long-chain acyl-CoA + NADPH. |
| Pathway | |
| Sequence similarities | Belongs to the luxC family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Luminescence |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
Gene Ontology (GO) | |
| Biological process | bioluminescence Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | acyl-CoA reductase activity Inferred from electronic annotation. Source: InterPro long-chain-fatty-acyl-CoA reductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 478 | 478 | Acyl-CoA reductase | PRO_0000220196 | |||
Sequences
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References
| [1] | "Nucleotide sequence of the luxC gene encoding fatty acid reductase of the lux operon from Photobacterium leiognathi." Lin J.-W., Chao Y.-F., Weng S.-F. Biochem. Biophys. Res. Commun. 191:314-318(1993) [PubMed: 8447834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 741. |
Cross-references
Sequence databases | |
|---|---|
| X65156 Genomic DNA. Translation: CAA46274.1. | |
| PIR | JC1475. |
3D structure databases | |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR016162. Ald_DHase_N. IPR008670. LuxC. [Graphical view] |
| Gene3D | G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| Pfam | PF05893. LuxC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | LUXC1_PHOLE | ||||||||
| Accession | Primary (citable) accession number: Q03324 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


