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Q03301

- SODM2_HALVD

UniProt

Q03301 - SODM2_HALVD

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Protein

Superoxide dismutase [Mn] 2

Gene
sod2, HVO_2913
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Binds 1 manganese ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi28 – 281Manganese By similarity
Metal bindingi75 – 751Manganese By similarity
Metal bindingi157 – 1571Manganese By similarity
Metal bindingi161 – 1611Manganese By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciHVOL309800:GCOK-2919-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] 2 (EC:1.15.1.1)
Gene namesi
Name:sod2
Ordered Locus Names:HVO_2913
OrganismiHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Taxonomic identifieri309800 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax
ProteomesiUP000008243: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Superoxide dismutase [Mn] 2PRO_0000160117Add
BLAST

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000013583.
KOiK04564.
OMAiRAYVPIG.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q03301-1 [UniParc]FASTAAdd to Basket

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MSYELDPLPY EYDALEPHIS EQVLTWHHDT HHQGYVNGWN AAEETLAENR    50
EAGEFGSSAG ALRNVTHNGS GHILHDLFWQ NMSPEGGDEP EGALAERIAE 100
DFGSYEAWKG EFEAAAGAAG GWALLVYDSF SNQLRNVVVD KHDQGALWGS 150
HPILALDVWE HSYYHDYGPA RGDFVSAFFE VVDWDEPAAR YEQAVELFE 199
Length:199
Mass (Da):22,297
Last modified:September 21, 2011 - v2
Checksum:i6315C33F3B7265CB
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti42 – 432AE → DD in AAA73376. 1 Publication
Sequence conflicti62 – 621L → V in AAA73376. 1 Publication
Sequence conflicti93 – 931A → L in AAA73376. 1 Publication
Sequence conflicti120 – 1201G → A in AAA73376. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M97487 Genomic DNA. Translation: AAA73376.1.
CP001956 Genomic DNA. Translation: ADE03299.1.
PIRiT50046.
RefSeqiWP_013035375.1. NC_013967.1.
YP_003536923.1. NC_013967.1.

Genome annotation databases

EnsemblBacteriaiADE03299; ADE03299; HVO_2913.
GeneIDi8924540.
KEGGihvo:HVO_2913.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M97487 Genomic DNA. Translation: AAA73376.1 .
CP001956 Genomic DNA. Translation: ADE03299.1 .
PIRi T50046.
RefSeqi WP_013035375.1. NC_013967.1.
YP_003536923.1. NC_013967.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE03299 ; ADE03299 ; HVO_2913 .
GeneIDi 8924540.
KEGGi hvo:HVO_2913.

Phylogenomic databases

HOGENOMi HOG000013583.
KOi K04564.
OMAi RAYVPIG.

Enzyme and pathway databases

BioCyci HVOL309800:GCOK-2919-MONOMER.

Family and domain databases

InterProi IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view ]
PANTHERi PTHR11404. PTHR11404. 1 hit.
Pfami PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000349. SODismutase. 1 hit.
PRINTSi PR01703. MNSODISMTASE.
SUPFAMi SSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEi PS00088. SOD_MN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of paralogous and orthologous members of the superoxide dismutase gene family from genera of the halophilic archaebacteria."
    Joshi P.B., Dennis P.P.
    J. Bacteriol. 175:1561-1571(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.

Entry informationi

Entry nameiSODM2_HALVD
AccessioniPrimary (citable) accession number: Q03301
Secondary accession number(s): D4GXS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi