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Reviewed, UniProtKB/Swiss-Prot Q03274 (PO22_POPJA)

Last modified September 22, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2
Alternative name(s):
    Retrovirus-related Pol polyprotein from type I retrotransposable element R2
Including the following 2 domains:
    1- Recommended name:
            Reverse transcriptase
              EC=2.7.7.49
    2- Recommended name:
            Endonuclease
OrganismPopillia japonica (Japanese beetle)
Taxonomic identifier7064 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaColeopteraPolyphagaScarabaeiformiaScarabaeidaeRutelinaePopillia

Protein attributes

Sequence length711 AA.
Sequence statusFragment.
Protein existencePredicted.

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Sequence similarities

Contains 1 reverse transcriptase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 711›711Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2
PRO_0000058500

Regions

Domain45 – 323279Reverse transcriptase
Region444 – 711268Nucleic acid-binding endonuclease

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q03274-1 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: EAA25C9085F12D04

FASTA71179,459
        10         20         30         40         50         60 
HTYRPIAREE IQCAIKGWKP SAPGSDGLTV QAITRTRLPR NFVQLHLLRG HVPTPWTAMR 

        70         80         90        100        110        120 
TTLIPKDGDL ENPSNWRPIT IASALQRLLH RILAKRLEAA VELHPAQKGY ARIDGTLVNS 

       130        140        150        160        170        180 
LLLDTYISSR REQRKTYNVV SLDVRKAFDT VSHSSICRAL QRLGIDEGTS NYITGSLSDS 

       190        200        210        220        230        240 
TTTIRVGPGS QTRKICIRRG VKQGDPLSPF LFNAVLDELL CSLQSTPGIG GTIGEEKIPV 

       250        260        270        280        290        300 
LAFADDLLLL EDNDVLLPTT LATVANFFRL RGMSLNAKKS VSISVAASGG VCIPRTKPFL 

       310        320        330        340        350        360 
RVDNVLLPVT DRMQTFRYLG HFFGLSGAAK PTVYNLSRWL KCVEAAPLKP EQKLSLIREH 

       370        380        390        400        410        420 
VVPKLLYGLQ NPSVTARTLR DADKLIRTTV KRCLHLHLHT PNQCFYARVR DGGLGLTDLR 

       430        440        450        460        470        480 
RSIPRIMLDR INARRSSDPM AVALFSCPSF DHLRGRLVAL AGDVPPSHFW REAIANHTTT 

       490        500        510        520        530        540 
KGLEAASDDP ASRSWIFRKP YGWSGKDFVR AIHLRTGNLP TKAIPSNPAG ERLCRGGCGK 

       550        560        570        580        590        600 
QATISHVLQR CPVVQPERIR RHNEIARKIA AHCRSKGWTV EEEPHIRHPL GHLYKPDIVI 

       610        620        630        640        650        660 
HREGLPSVVC DVQVSWDGYE PLDEAWRNKQ RTYDHDLFRT AAGRRWPGKT FLHLPAILGA 

       670        680        690        700        710 
RGIWPRCNSE TASALAFTNQ LKASWLHSCL KWDSTLHTSF MRAVWSRQAG A 

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References

[1]"Sequence relationship of retrotransposable elements R1 and R2 within and between divergent insect species."
Burke W.D., Eickbush D.G., Xiong Y., Jakubczak J.L., Eickbush T.H.
Mol. Biol. Evol. 10:163-185(1993) [PubMed: 8383793] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Retrotransposable elements R1 and R2 interrupt the rRNA genes of most insects."
Jakubczak J.L., Burke W.D., Eickbush T.H.
Proc. Natl. Acad. Sci. U.S.A. 88:3295-3299(1991) [PubMed: 1849649] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 534-551.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L00947 Genomic DNA. Translation: AAA29785.1.
PIRH44490.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA2.7.7.49. 295234.

Family and domain databases

InterProIPR000477. Reverse_transcriptase.
IPR015706. Reverse_transcriptase-related.
[Graphical view]
PANTHERPTHR19446. Rev_txptase. 1 hit.
PfamPF00078. RVT_1. 1 hit.
[Graphical view]
PROSITEPS50878. RT_POL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePO22_POPJA
AccessionPrimary (citable) accession number: Q03274
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: September 22, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents