Q03272 (PO14_NASVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 4 Alternative name(s): Retrovirus-related Pol polyprotein from type I retrotransposable element R1 4 Including the following 2 domains: Reverse transcriptase EC=2.7.7.49 Endonuclease
Organism	Nasonia vitripennis (Parasitic wasp)
Taxonomic identifier	7425 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Hymenoptera › Apocrita › Chalcidoidea › Pteromalidae › Pteromalinae › Nasonia

Protein attributes

Sequence length	392 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Sequence similarities	Contains 1 reverse transcriptase domain.

Ontologies

Keywords
Molecular function	Endonuclease Hydrolase Nuclease Nucleotidyltransferase RNA-directed DNA polymerase Transferase
Technical term	Transposable element
Gene Ontology (GO)
Molecular function	RNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 392	›392	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 4		PRO_0000058496
Regions
	Domain	‹1 – 230	›230	Reverse transcriptase
	Region	231 – 392	162	Nucleic acid-binding endonuclease
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q03272 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: D644BD53EDAD77F6	FASTA	392	43,758
	10 20 30 40 50 60 PFADDLAVLV EGDSRAEIEK VGKAVVKHIV ERCSAIKLEV SESKTVGIFV KKPKVVGSKA 70 80 90 100 110 120 VKINRKDCRK GGARNLKIEL GGKSISFEQS VRYLGVHFDA NLGISAHCKY LREKLVPLFS 130 140 150 160 170 180 DLRKLAQCQW GLGHKALETI YKGVFVPTVC YASARWYKEG AHTDRILEDL HRQILIAITR 190 200 210 220 230 240 CYRSTSYEAA CVLAGTLPIC IQLRVSVAKY HLRKGEDAEI GGVVIRRRPE GLKENYNRVL 250 260 270 280 290 300 EVANEMWQAR WEASEQGNAT RELFFPDVVA RVKSDWIRPD HFTSQVLTGH GYYNEKLHQL 310 320 330 340 350 360 SLAKAAACIC CGEPDNNLHF LLECPAFAEF RDELITPVSG GLEAPEATLM LVSSPEGFAA 370 380 390 LKEYSRVAFE CKRQLENALT ESDEGLSSES EE

References

[1]	"Sequence relationship of retrotransposable elements R1 and R2 within and between divergent insect species." Burke W.D., Eickbush D.G., Xiong Y., Jakubczak J.L., Eickbush T.H. Mol. Biol. Evol. 10:163-185(1993) [PubMed: 8383793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	L00943 Genomic DNA. Translation: AAA30340.1.
PIR	E44490.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS50878. RT_POL. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PO14_NASVI

Accession

Primary (citable) accession number: Q03272

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	May 31, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)