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Protein

37S ribosomal protein S17, mitochondrial

Gene

MRPS17

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May have a meiosis-specific role as it accumulates during the middle stage of sporulation.1 Publication

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. mitochondrial translation Source: SGD
  2. sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

Sporulation

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-32876-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein S17, mitochondrial
Gene namesi
Name:MRPS17
Ordered Locus Names:YMR188C
ORF Names:YM8010.18C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome XIII

Organism-specific databases

CYGDiYMR188c.
EuPathDBiFungiDB:YMR188C.
SGDiS000004800. MRPS17.

Subcellular locationi

  1. Mitochondrion 3 Publications

GO - Cellular componenti

  1. mitochondrial small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23723737S ribosomal protein S17, mitochondrialPRO_0000128525Add
BLAST

Proteomic databases

MaxQBiQ03246.
PaxDbiQ03246.

Expressioni

Gene expression databases

GenevestigatoriQ03246.

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).1 Publication

Protein-protein interaction databases

BioGridi35366. 42 interactions.
DIPiDIP-6688N.
IntActiQ03246. 6 interactions.
MINTiMINT-615939.

Structurei

3D structure databases

ProteinModelPortaliQ03246.
SMRiQ03246. Positions 3-83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S17P family.Curated

Phylogenomic databases

eggNOGiCOG0186.
HOGENOMiHOG000248070.
InParanoidiQ03246.
KOiK02961.
OMAiIIRNKGQ.
OrthoDBiEOG7XWQ1B.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01345_B. Ribosomal_S17_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
[Graphical view]
PANTHERiPTHR10744. PTHR10744. 1 hit.
PfamiPF00366. Ribosomal_S17. 1 hit.
[Graphical view]
ProDomiPD001295. Ribosomal_S17. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50249. SSF50249. 1 hit.

Sequencei

Sequence statusi: Complete.

Q03246-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARQNFLGLV VSQGKMQKTV KVRVETKVFN KKINKELFHR RDYLVHDEGE
60 70 80 90 100
ISREGDLVRI EATRPLSKRK FFAIAEIIRN KGQQFALYES EAQLSVAKEE
110 120 130 140 150
AQKAKEFLDK RSVRENKLNE KTTLLRDIRT IQDALSSGST PKELLEIKQR
160 170 180 190 200
YGIQDFSQET VRQLLQLDIS GLEVNLEKQR SLIDRIQTRL SELLSNDLKC
210 220 230
DQFLKDHGVE DPLTLKKNIK KNLLRKHVMM DMQQPSQ
Length:237
Mass (Da):27,635
Last modified:November 1, 1997 - v1
Checksum:iF9D606434D1310D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49808 Genomic DNA. Translation: CAA89921.1.
U20641 Genomic DNA. Translation: AAB18932.1.
BK006946 Genomic DNA. Translation: DAA10086.1.
PIRiS55135.
RefSeqiNP_013913.1. NM_001182694.1.

Genome annotation databases

EnsemblFungiiYMR188C; YMR188C; YMR188C.
GeneIDi855226.
KEGGisce:YMR188C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49808 Genomic DNA. Translation: CAA89921.1.
U20641 Genomic DNA. Translation: AAB18932.1.
BK006946 Genomic DNA. Translation: DAA10086.1.
PIRiS55135.
RefSeqiNP_013913.1. NM_001182694.1.

3D structure databases

ProteinModelPortaliQ03246.
SMRiQ03246. Positions 3-83.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35366. 42 interactions.
DIPiDIP-6688N.
IntActiQ03246. 6 interactions.
MINTiMINT-615939.

Proteomic databases

MaxQBiQ03246.
PaxDbiQ03246.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR188C; YMR188C; YMR188C.
GeneIDi855226.
KEGGisce:YMR188C.

Organism-specific databases

CYGDiYMR188c.
EuPathDBiFungiDB:YMR188C.
SGDiS000004800. MRPS17.

Phylogenomic databases

eggNOGiCOG0186.
HOGENOMiHOG000248070.
InParanoidiQ03246.
KOiK02961.
OMAiIIRNKGQ.
OrthoDBiEOG7XWQ1B.

Enzyme and pathway databases

BioCyciYEAST:G3O-32876-MONOMER.

Miscellaneous databases

NextBioi978756.
PROiQ03246.

Gene expression databases

GenevestigatoriQ03246.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01345_B. Ribosomal_S17_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
[Graphical view]
PANTHERiPTHR10744. PTHR10744. 1 hit.
PfamiPF00366. Ribosomal_S17. 1 hit.
[Graphical view]
ProDomiPD001295. Ribosomal_S17. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50249. SSF50249. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae."
    Sinclair D.A., Dawes I.W.
    Genetics 140:1213-1222(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-47.
  4. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  8. "Analysis of the meiotic role of the mitochondrial ribosomal proteins Mrps17 and Mrpl37 in Saccharomyces cerevisiae."
    Hanlon S.E., Xu Z., Norris D.N., Vershon A.K.
    Yeast 21:1241-1252(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiRT17_YEAST
AccessioniPrimary (citable) accession number: Q03246
Secondary accession number(s): D6W012, Q02523
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 29, 2015
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2810 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.