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Q03167 (TGBR3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 131. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transforming growth factor beta receptor type 3

Short name=TGF-beta receptor type 3
Short name=TGFR-3
Alternative name(s):
Betaglycan
Transforming growth factor beta receptor III
Short name=TGF-beta receptor type III
Gene names
Name:TGFBR3
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length851 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.

Subunit structure

Interacts with TCTEX1D4. Ref.7

Subcellular location

Secreted. Secretedextracellular space. Cell membrane; Single-pass type I membrane protein Potential. Note: Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.

Post-translational modification

Extensively modified by glycosaminoglycan groups (GAG).

Sequence similarities

Contains 1 ZP domain.

Sequence caution

The sequence AAA67061.1 differs from that shown. Reason: Frameshift at positions 70, 73, 349 and 350.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
Secreted
   Coding sequence diversityAlternative splicing
Polymorphism
   DomainSignal
Transmembrane
Transmembrane helix
   Molecular functionReceptor
   PTMDisulfide bond
Glycoprotein
Proteoglycan
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processBMP signaling pathway

Inferred from direct assay PubMed 18184661. Source: BHF-UCL

blastocyst development

Inferred from electronic annotation. Source: Ensembl

blood vessel development

Inferred from electronic annotation. Source: Ensembl

cardiac epithelial to mesenchymal transition

Inferred from direct assay PubMed 18184661. Source: BHF-UCL

cardiac muscle cell proliferation

Inferred from sequence or structural similarity. Source: BHF-UCL

cell growth

Inferred from sequence or structural similarity Ref.1. Source: BHF-UCL

cell migration

Inferred from sequence or structural similarity. Source: BHF-UCL

definitive erythrocyte differentiation

Inferred from sequence or structural similarity. Source: BHF-UCL

definitive hemopoiesis

Inferred from sequence or structural similarity. Source: BHF-UCL

epithelial to mesenchymal transition

Inferred from direct assay PubMed 18184661. Source: BHF-UCL

heart morphogenesis

Inferred from sequence or structural similarity. Source: BHF-UCL

heart trabecula formation

Inferred from sequence or structural similarity. Source: BHF-UCL

immune response

Inferred from mutant phenotype PubMed 16886151. Source: BHF-UCL

intracellular signal transduction

Inferred from mutant phenotype PubMed 14557487. Source: BHF-UCL

liver development

Inferred from sequence or structural similarity. Source: BHF-UCL

negative regulation of cellular component movement

Inferred from direct assay PubMed 17999987. Source: BHF-UCL

negative regulation of epithelial cell migration

Inferred from electronic annotation. Source: Ensembl

negative regulation of epithelial cell proliferation

Inferred from sequence or structural similarity. Source: BHF-UCL

negative regulation of epithelial to mesenchymal transition

Inferred from electronic annotation. Source: Ensembl

negative regulation of transforming growth factor beta receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

organ regeneration

Inferred from electronic annotation. Source: Ensembl

palate development

Inferred from sequence or structural similarity. Source: BHF-UCL

pathway-restricted SMAD protein phosphorylation

Inferred from mutant phenotype PubMed 11157754. Source: BHF-UCL

positive regulation of NF-kappaB transcription factor activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of transforming growth factor beta receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

regulation of protein binding

Inferred from electronic annotation. Source: Ensembl

response to follicle-stimulating hormone

Inferred from direct assay PubMed 14557487. Source: BHF-UCL

response to hypoxia

Inferred from electronic annotation. Source: Ensembl

response to luteinizing hormone

Inferred from direct assay PubMed 14557487. Source: BHF-UCL

response to prostaglandin E

Inferred from direct assay PubMed 14557487. Source: BHF-UCL

transforming growth factor beta receptor complex assembly

Inferred from electronic annotation. Source: Ensembl

transforming growth factor beta receptor signaling pathway

Inferred from direct assay PubMed 12958365. Source: BHF-UCL

ventricular cardiac muscle tissue morphogenesis

Inferred from sequence or structural similarity. Source: BHF-UCL

   Cellular_componentcell surface

Inferred from sequence or structural similarity. Source: BHF-UCL

endoplasmic reticulum

Inferred from electronic annotation. Source: Ensembl

external side of plasma membrane

Inferred from direct assay PubMed 12958365. Source: BHF-UCL

extracellular space

Traceable author statement. Source: BHF-UCL

extracellular vesicular exosome

Inferred from direct assay PubMed 19056867PubMed 19199708PubMed 23376485. Source: UniProt

inhibin-betaglycan-ActRII complex

Inferred from direct assay PubMed 10746731. Source: BHF-UCL

integral component of plasma membrane

Inferred from sequence or structural similarity. Source: BHF-UCL

proteinaceous extracellular matrix

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionPDZ domain binding

Inferred from sequence or structural similarity. Source: BHF-UCL

SMAD binding

Inferred from mutant phenotype PubMed 11157754. Source: BHF-UCL

coreceptor activity

Inferred from direct assay PubMed 10746731. Source: BHF-UCL

glycosaminoglycan binding

Inferred from sequence or structural similarity. Source: BHF-UCL

heparin binding

Inferred from sequence or structural similarity Ref.1. Source: BHF-UCL

protein binding

Inferred from physical interaction PubMed 11546783PubMed 20856203. Source: IntAct

transforming growth factor beta binding

Inferred from direct assay PubMed 11157754PubMed 12958365. Source: BHF-UCL

transforming growth factor beta receptor activity, type III

Inferred from direct assay PubMed 10746731PubMed 11157754. Source: BHF-UCL

transforming growth factor beta receptor binding

Inferred from sequence or structural similarity Ref.1. Source: BHF-UCL

transforming growth factor beta-activated receptor activity

Inferred from direct assay PubMed 12958365. Source: BHF-UCL

type II transforming growth factor beta receptor binding

Inferred from direct assay PubMed 11157754. Source: BHF-UCL

Complete GO annotation...

Binary interactions

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q03167-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q03167-2)

The sequence of this isoform differs from the canonical sequence as follows:
     359-359: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 851831Transforming growth factor beta receptor type 3
PRO_0000041663

Regions

Topological domain21 – 787767Extracellular Potential
Transmembrane788 – 80922Helical; Potential
Topological domain810 – 85142Cytoplasmic Potential
Domain455 – 730276ZP
Region737 – 75115Interaction with TGF-beta ligand By similarity

Amino acid modifications

Glycosylation1411N-linked (GlcNAc...) Potential
Glycosylation4921N-linked (GlcNAc...) Potential
Glycosylation5341O-linked (Xyl...) (glycosaminoglycan) By similarity
Glycosylation5451O-linked (Xyl...) (glycosaminoglycan) By similarity
Glycosylation5711N-linked (GlcNAc...) Potential
Glycosylation5901N-linked (GlcNAc...) Potential
Glycosylation6971N-linked (GlcNAc...) Potential
Disulfide bond639 ↔ 705 By similarity
Disulfide bond660 ↔ 730 By similarity
Disulfide bond710 ↔ 723 By similarity

Natural variations

Alternative sequence3591Missing in isoform 2.
VSP_040018
Natural variant141S → N. Ref.3
Corresponds to variant rs17884205 [ dbSNP | Ensembl ].
VAR_020891
Natural variant151S → F. Ref.1 Ref.2 Ref.3
Corresponds to variant rs1805110 [ dbSNP | Ensembl ].
VAR_014920
Natural variant1631W → L. Ref.3
Corresponds to variant rs17885124 [ dbSNP | Ensembl ].
VAR_020892
Natural variant3511F → I.
Corresponds to variant rs11466592 [ dbSNP | Ensembl ].
VAR_057499
Natural variant6351A → T. Ref.3
Corresponds to variant rs17882578 [ dbSNP | Ensembl ].
VAR_020893
Natural variant7651G → R. Ref.3
Corresponds to variant rs17882828 [ dbSNP | Ensembl ].
VAR_020894
Natural variant7771P → S.
Corresponds to variant rs35352606 [ dbSNP | Ensembl ].
VAR_066625

Experimental info

Sequence conflict891P → S in BAF84034. Ref.4
Sequence conflict2381I → V in BAF84034. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 2, 2010. Version 3.
Checksum: AEC56C4477C003B2

FASTA85193,499
        10         20         30         40         50         60 
MTSHYVIAIF ALMSSCLATA GPEPGALCEL SPVSASHPVQ ALMESFTVLS GCASRGTTGL 

        70         80         90        100        110        120 
PQEVHVLNLR TAGQGPGQLQ REVTLHLNPI SSVHIHHKSV VFLLNSPHPL VWHLKTERLA 

       130        140        150        160        170        180 
TGVSRLFLVS EGSVVQFSSA NFSLTAETEE RNFPHGNEHL LNWARKEYGA VTSFTELKIA 

       190        200        210        220        230        240 
RNIYIKVGED QVFPPKCNIG KNFLSLNYLA EYLQPKAAEG CVMSSQPQNE EVHIIELITP 

       250        260        270        280        290        300 
NSNPYSAFQV DITIDIRPSQ EDLEVVKNLI LILKCKKSVN WVIKSFDVKG SLKIIAPNSI 

       310        320        330        340        350        360 
GFGKESERSM TMTKSIRDDI PSTQGNLVKW ALDNGYSPIT SYTMAPVANR FHLRLENNAE 

       370        380        390        400        410        420 
EMGDEEVHTI PPELRILLDP GALPALQNPP IRGGEGQNGG LPFPFPDISR RVWNEEGEDG 

       430        440        450        460        470        480 
LPRPKDPVIP SIQLFPGLRE PEEVQGSVDI ALSVKCDNEK MIVAVEKDSF QASGYSGMDV 

       490        500        510        520        530        540 
TLLDPTCKAK MNGTHFVLES PLNGCGTRPR WSALDGVVYY NSIVIQVPAL GDSSGWPDGY 

       550        560        570        580        590        600 
EDLESGDNGF PGDMDEGDAS LFTRPEIVVF NCSLQQVRNP SSFQEQPHGN ITFNMELYNT 

       610        620        630        640        650        660 
DLFLVPSQGV FSVPENGHVY VEVSVTKAEQ ELGFAIQTCF ISPYSNPDRM SHYTIIENIC 

       670        680        690        700        710        720 
PKDESVKFYS PKRVHFPIPQ ADMDKKRFSF VFKPVFNTSL LFLQCELTLC TKMEKHPQKL 

       730        740        750        760        770        780 
PKCVPPDEAC TSLDASIIWA MMQNKKTFTK PLAVIHHEAE SKEKGPSMKE PNPISPPIFH 

       790        800        810        820        830        840 
GLDTLTVMGI AFAAFVIGAL LTGALWYIYS HTGETAGRQQ VPTSPPASEN SSAAHSIGST 

       850 
QSTPCSSSST A 

« Hide

Isoform 2 [UniParc].

Checksum: 1469BB567BD05230
Show »

FASTA85093,428

References

« Hide 'large scale' references
[1]"Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors."
Moren A., Ichijo H., Miyazono K.
Biochem. Biophys. Res. Commun. 189:356-362(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT PHE-15.
Tissue: Placenta.
[2]"Eleven single nucleotide polymorphisms and one triple nucleotide insertion of the human TGF-beta III receptor gene."
Zippert R., Baessler A., Holmer S.R., Hengstenberg C., Schunkert H.
J. Hum. Genet. 45:250-253(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT PHE-15.
Tissue: Blood.
[3]NIEHS SNPs program
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS ASN-14; PHE-15; LEU-163; THR-635 AND ARG-765.
[4]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Tongue.
[5]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Tissue: Brain.
[7]"Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors."
Meng Q.-J., Lux A., Holloschi A., Li J., Hughes J.M.X., Foerg T., McCarthy J.E.G., Heagerty A.M., Kioschis P., Hafner M., Garland J.M.
J. Biol. Chem. 281:37069-37080(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH TCTEX1D4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L07594 mRNA. Translation: AAA67061.1. Frameshift.
AJ251961 mRNA. Translation: CAB64374.1.
AY796304 Genomic DNA. Translation: AAV50003.1.
AK291345 mRNA. Translation: BAF84034.1.
AL162263, AL390780, AL445992 Genomic DNA. Translation: CAI22636.1.
AL162263 expand/collapse EMBL AC list , AC099334, AL390780, AL445992 Genomic DNA. Translation: CAI22637.1.
AL390780, AL162263, AL445992 Genomic DNA. Translation: CAI14570.1.
AL390780 expand/collapse EMBL AC list , AC099334, AL162263, AL445992 Genomic DNA. Translation: CAI14571.1.
AL445992, AL162263, AL390780 Genomic DNA. Translation: CAI13392.1.
AL445992 expand/collapse EMBL AC list , AC099334, AL162263, AL390780 Genomic DNA. Translation: CAI13393.1.
BC126116 mRNA. Translation: AAI26117.1.
BC136295 mRNA. Translation: AAI36296.1.
CCDSCCDS30770.1. [Q03167-1]
CCDS55614.1. [Q03167-2]
PIRJC1350.
RefSeqNP_001182612.1. NM_001195683.1. [Q03167-2]
NP_001182613.1. NM_001195684.1. [Q03167-2]
NP_003234.2. NM_003243.4. [Q03167-1]
XP_006710930.1. XM_006710867.1. [Q03167-1]
XP_006710931.1. XM_006710868.1. [Q03167-1]
UniGeneHs.482390.
Hs.735919.

3D structure databases

ProteinModelPortalQ03167.
SMRQ03167. Positions 587-755.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid112907. 4 interactions.
DIPDIP-5940N.
IntActQ03167. 4 interactions.
MINTMINT-1785606.
STRING9606.ENSP00000212355.

PTM databases

PhosphoSiteQ03167.

Polymorphism databases

DMDM311033535.

Proteomic databases

MaxQBQ03167.
PaxDbQ03167.
PRIDEQ03167.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000212355; ENSP00000212355; ENSG00000069702. [Q03167-1]
ENST00000370399; ENSP00000359426; ENSG00000069702. [Q03167-2]
ENST00000465892; ENSP00000432638; ENSG00000069702. [Q03167-2]
ENST00000525962; ENSP00000436127; ENSG00000069702. [Q03167-1]
GeneID7049.
KEGGhsa:7049.
UCSCuc001doh.3. human. [Q03167-1]
uc001doi.3. human. [Q03167-2]

Organism-specific databases

CTD7049.
GeneCardsGC01M092145.
H-InvDBHIX0028622.
HGNCHGNC:11774. TGFBR3.
HPACAB018971.
HPA008257.
MIM600742. gene.
neXtProtNX_Q03167.
Orphanet231160. Familial cerebral saccular aneurysm.
PharmGKBPA36487.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG40778.
HOGENOMHOG000090193.
HOVERGENHBG057515.
KOK05843.
OMAIENICPK.
OrthoDBEOG72ZCDK.
PhylomeDBQ03167.
TreeFamTF337375.

Gene expression databases

ArrayExpressQ03167.
BgeeQ03167.
CleanExHS_TGFBR3.
GenevestigatorQ03167.

Family and domain databases

InterProIPR001507. ZP_dom.
IPR017977. ZP_dom_CS.
[Graphical view]
PfamPF00100. Zona_pellucida. 1 hit.
[Graphical view]
PRINTSPR00023. ZPELLUCIDA.
SMARTSM00241. ZP. 1 hit.
[Graphical view]
PROSITEPS00682. ZP_1. 1 hit.
PS51034. ZP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTGFBR3. human.
GeneWikiTGFBR3.
GenomeRNAi7049.
NextBio27547.
PROQ03167.
SOURCESearch...

Entry information

Entry nameTGBR3_HUMAN
AccessionPrimary (citable) accession number: Q03167
Secondary accession number(s): A0AUW8 expand/collapse secondary AC list , A8K5N0, B9EG88, Q5T2T4, Q5U731, Q9UGI2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 2, 2010
Last modified: July 9, 2014
This is version 131 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM