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Protein

MYND-type zinc finger protein MUB1

Gene

MUB1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the determination of the onset of polarized growth. Required for the ubiquitin-dependent degradation of RPN4. Cooperates with UBR2 to transfer ubiquitin from RAD6 to RPN4.1 Publication

Miscellaneous

Present with 125 molecules/cell in log phase SD medium.1 Publication
Is a short-lived protein whose degradation is dependent on the UBR2/RAD6 ubiquitin-protein ligase.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri514 – 555MYND-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

GO - Biological processi

  • ubiquitin-dependent protein catabolic process Source: SGD

Keywordsi

Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32800-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
MYND-type zinc finger protein MUB1
Alternative name(s):
Multi-budding protein
Gene namesi
Name:MUB1
Ordered Locus Names:YMR100W
ORF Names:YM6543.07
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR100W
SGDiS000004706 MUB1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002183231 – 620MYND-type zinc finger protein MUB1Add BLAST620

Proteomic databases

MaxQBiQ03162
PaxDbiQ03162
PRIDEiQ03162

Interactioni

Subunit structurei

Interacts with UBR2 and RPN4.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi35276, 323 interactors
DIPiDIP-6429N
IntActiQ03162, 6 interactors
MINTiQ03162
STRINGi4932.YMR100W

Structurei

3D structure databases

ProteinModelPortaliQ03162
SMRiQ03162
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The MYND-type zinc finger is essential for the ubiquitin-dependent degradation of RPN4.1 Publication

Sequence similaritiesi

Belongs to the MUB1/samB family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri514 – 555MYND-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000066045
InParanoidiQ03162
OMAiNLCRKDD
OrthoDBiEOG092C13YU

Family and domain databases

InterProiView protein in InterPro
IPR002893 Znf_MYND
PfamiView protein in Pfam
PF01753 zf-MYND, 1 hit
PROSITEiView protein in PROSITE
PS01360 ZF_MYND_1, 1 hit
PS50865 ZF_MYND_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q03162-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDSNHRSLT SNKPIVTITS TVYDRRALDI NSSIPLINSL NYLTYLTSNS
60 70 80 90 100
SKVRETVAND GALERLVSIL RSCHLSLFEL LDLDLENFNE HENIKDLWKE
110 120 130 140 150
KRLALCAWKW TLTFQCLVLT GTRGTEQIRK KVVMSGVLSV LVTVLDNYLL
160 170 180 190 200
YHKNYDFIKD QTMTFDFKGI TTETMYKFMR KDENETYQQY IEFITGQDKL
210 220 230 240 250
KLSTDKNFLN ERLVAPSMTI PTDFSDIWGR FADLASNFEP DQERHDDDID
260 270 280 290 300
IDSEVESENF DAHKNFFSQP DINRPTISTP REFFLGRIVP KQDDVIWSLQ
310 320 330 340 350
LLAFVSKYTY MKSTLQNVEL VESLSFRSMA YKIKQRISEE NDLEEQERDV
360 370 380 390 400
TVKLSSLYPY LSKNPENNSK VKALDTSKMD PFFKELEELS NRCQQEEQNE
410 420 430 440 450
ICNNHCPVLN LFERYRVPKP SDDNAYGKDK ERINLRKKIS DNFERRWSYD
460 470 480 490 500
KMKKELTNIV YKNKVLTNVV NIFPLVEKYT VSAENTHDVI YWSSVIMRNS
510 520 530 540 550
CRKNEILGVR QCANFSCGKW EDFPRQFAKC RRCKRTKYCS RKCQLKAWGY
560 570 580 590 600
HRYWCHEVGS SHMRSTNTTT GVNTPNEPSS LNATATTAAD VSNSTSTFTP
610 620
NISTTVPDEI SNRDENSIPE
Length:620
Mass (Da):72,251
Last modified:November 1, 1997 - v1
Checksum:iE38AA57377082966
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49807 Genomic DNA Translation: CAA89901.1
BK006946 Genomic DNA Translation: DAA09997.1
PIRiS55086
RefSeqiNP_013818.1, NM_001182600.1

Genome annotation databases

EnsemblFungiiYMR100W; YMR100W; YMR100W
GeneIDi855126
KEGGisce:YMR100W

Similar proteinsi

Entry informationi

Entry nameiMUB1_YEAST
AccessioniPrimary (citable) accession number: Q03162
Secondary accession number(s): D6VZS3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names
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