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Q03153 (ATP25_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATPase synthesis protein 25, mitochondrial
Alternative name(s):
OLI1 mRNA stabilization factor
Gene names
Name:ATP25
Ordered Locus Names:YMR098C
ORF Names:YM6543.05C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length612 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

mRNA stabilization factor specific for the 0.95 kb OLI1 mRNA. Also involved in OLI1 ring formation. Ref.6

Subcellular location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side Ref.3 Ref.5 Ref.6.

Miscellaneous

Present with 2430 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ATP25 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 1414Mitochondrion Potential
Chain15 – 612598ATPase synthesis protein 25, mitochondrial
PRO_0000203288

Sequences

Sequence LengthMass (Da)Tools
Q03153 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: CC0B89608796A24F

FASTA61270,414
        10         20         30         40         50         60 
MNKFCLLPFH GKRIGVANIP FTILFKKGPY FLHSHITAVY YSTKGKNDSH EQSRVSKKST 

        70         80         90        100        110        120 
FTPLETPWYL RIVDNEKELM EGKKNNHHTM NKELEIPKTS PNSLRKIADL LTGKLGLDDF 

       130        140        150        160        170        180 
LVFDLRKKSP NSVSAVNKLG DFMVICTARS TKHCHKSFLE LNKFLKHEFC SSAYVEGNFN 

       190        200        210        220        230        240 
ERQESRRKRR LARKSNLSKL LGRSSECSAK DLNSEAWYMI DCRVDGIFVN ILTQRRRNEL 

       250        260        270        280        290        300 
NLEELYAPEN EKSKFQNIDS GNVPTISGVN EISSNNNILL GLRRLAQQRR RYSTINPNGL 

       310        320        330        340        350        360 
SNLRYFLQKE DFKGANKIIQ SSSGTETHNI RTLEHVKNTL KDLVGQERKV DVVQWKSLFD 

       370        380        390        400        410        420 
EHSTFLTINQ SAAYWPLRLE YAILLNKADP QFYSDRVFLK DYLLLKKSLG QELIREDLIA 

       430        440        450        460        470        480 
LLEMVLKTQH SSHSYFNLVK QNRVIIRALN LFKGLQTEDD GSVVYDEVVI SLLLNSMVAD 

       490        500        510        520        530        540 
ERVKLRSLYE TIDHIFQTFG DKLTSGMIVS ILQNLAKIKD WNKLLQVWEA ITPTEGEGQD 

       550        560        570        580        590        600 
KRPWNEFINV INQSGDSHVI SKIVNNGHLL WIRRLNVNVT PELCNSIKAL LKTAGMENST 

       610 
LEEFLVRGTN NQ 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"ATP25, a new nuclear gene of Saccharomyces cerevisiae required for expression and assembly of the Atp9p subunit of mitochondrial ATPase."
Zeng X., Barros M.H., Shulman T., Tzagoloff A.
Mol. Biol. Cell 19:1366-1377(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49807 Genomic DNA. Translation: CAA89899.1.
BK006946 Genomic DNA. Translation: DAA09995.1.
PIRS55084.
RefSeqNP_013816.1. NM_001182598.1.

3D structure databases

ProteinModelPortalQ03153.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35273. 7 interactions.
IntActQ03153. 2 interactions.
MINTMINT-2492603.
STRING4932.YMR098C.

Proteomic databases

MaxQBQ03153.
PaxDbQ03153.
PeptideAtlasQ03153.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR098C; YMR098C; YMR098C.
GeneID855123.
KEGGsce:YMR098C.

Organism-specific databases

CYGDYMR098c.
SGDS000004704. ATP25.

Phylogenomic databases

eggNOGNOG41172.
OMATETHNIR.
OrthoDBEOG70CRGD.

Enzyme and pathway databases

BioCycYEAST:G3O-32798-MONOMER.

Gene expression databases

GenevestigatorQ03153.

Family and domain databases

InterProIPR025210. ATP25_mRNA_stabil_dom.
IPR025656. Oligomer_dom.
[Graphical view]
PfamPF13929. mRNA_stabil. 1 hit.
PF02410. Oligomerisation. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio978482.

Entry information

Entry nameATP25_YEAST
AccessionPrimary (citable) accession number: Q03153
Secondary accession number(s): D6VZS1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families