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Q03153

- ATP25_YEAST

UniProt

Q03153 - ATP25_YEAST

Protein

ATPase synthesis protein 25, mitochondrial

Gene

ATP25

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    mRNA stabilization factor specific for the 0.95 kb OLI1 mRNA. Also involved in OLI1 ring formation.1 Publication

    GO - Biological processi

    1. mitochondrial proton-transporting ATP synthase complex assembly Source: SGD
    2. mRNA stabilization Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32798-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATPase synthesis protein 25, mitochondrial
    Alternative name(s):
    OLI1 mRNA stabilization factor
    Gene namesi
    Name:ATP25
    Ordered Locus Names:YMR098C
    ORF Names:YM6543.05C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYMR098c.
    SGDiS000004704. ATP25.

    Subcellular locationi

    Mitochondrion inner membrane 3 Publications; Peripheral membrane protein 3 Publications; Matrix side 3 Publications

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: SGD

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 1414MitochondrionSequence AnalysisAdd
    BLAST
    Chaini15 – 612598ATPase synthesis protein 25, mitochondrialPRO_0000203288Add
    BLAST

    Proteomic databases

    MaxQBiQ03153.
    PaxDbiQ03153.
    PeptideAtlasiQ03153.

    Expressioni

    Gene expression databases

    GenevestigatoriQ03153.

    Interactioni

    Protein-protein interaction databases

    BioGridi35273. 7 interactions.
    IntActiQ03153. 2 interactions.
    MINTiMINT-2492603.
    STRINGi4932.YMR098C.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03153.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP25 family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG41172.
    OMAiTETHNIR.
    OrthoDBiEOG70CRGD.

    Family and domain databases

    InterProiIPR025210. ATP25_mRNA_stabil_dom.
    IPR025656. Oligomer_dom.
    [Graphical view]
    PfamiPF13929. mRNA_stabil. 1 hit.
    PF02410. Oligomerisation. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q03153-1 [UniParc]FASTAAdd to Basket

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    MNKFCLLPFH GKRIGVANIP FTILFKKGPY FLHSHITAVY YSTKGKNDSH    50
    EQSRVSKKST FTPLETPWYL RIVDNEKELM EGKKNNHHTM NKELEIPKTS 100
    PNSLRKIADL LTGKLGLDDF LVFDLRKKSP NSVSAVNKLG DFMVICTARS 150
    TKHCHKSFLE LNKFLKHEFC SSAYVEGNFN ERQESRRKRR LARKSNLSKL 200
    LGRSSECSAK DLNSEAWYMI DCRVDGIFVN ILTQRRRNEL NLEELYAPEN 250
    EKSKFQNIDS GNVPTISGVN EISSNNNILL GLRRLAQQRR RYSTINPNGL 300
    SNLRYFLQKE DFKGANKIIQ SSSGTETHNI RTLEHVKNTL KDLVGQERKV 350
    DVVQWKSLFD EHSTFLTINQ SAAYWPLRLE YAILLNKADP QFYSDRVFLK 400
    DYLLLKKSLG QELIREDLIA LLEMVLKTQH SSHSYFNLVK QNRVIIRALN 450
    LFKGLQTEDD GSVVYDEVVI SLLLNSMVAD ERVKLRSLYE TIDHIFQTFG 500
    DKLTSGMIVS ILQNLAKIKD WNKLLQVWEA ITPTEGEGQD KRPWNEFINV 550
    INQSGDSHVI SKIVNNGHLL WIRRLNVNVT PELCNSIKAL LKTAGMENST 600
    LEEFLVRGTN NQ 612
    Length:612
    Mass (Da):70,414
    Last modified:November 1, 1997 - v1
    Checksum:iCC0B89608796A24F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49807 Genomic DNA. Translation: CAA89899.1.
    BK006946 Genomic DNA. Translation: DAA09995.1.
    PIRiS55084.
    RefSeqiNP_013816.1. NM_001182598.1.

    Genome annotation databases

    EnsemblFungiiYMR098C; YMR098C; YMR098C.
    GeneIDi855123.
    KEGGisce:YMR098C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49807 Genomic DNA. Translation: CAA89899.1 .
    BK006946 Genomic DNA. Translation: DAA09995.1 .
    PIRi S55084.
    RefSeqi NP_013816.1. NM_001182598.1.

    3D structure databases

    ProteinModelPortali Q03153.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35273. 7 interactions.
    IntActi Q03153. 2 interactions.
    MINTi MINT-2492603.
    STRINGi 4932.YMR098C.

    Proteomic databases

    MaxQBi Q03153.
    PaxDbi Q03153.
    PeptideAtlasi Q03153.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YMR098C ; YMR098C ; YMR098C .
    GeneIDi 855123.
    KEGGi sce:YMR098C.

    Organism-specific databases

    CYGDi YMR098c.
    SGDi S000004704. ATP25.

    Phylogenomic databases

    eggNOGi NOG41172.
    OMAi TETHNIR.
    OrthoDBi EOG70CRGD.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32798-MONOMER.

    Miscellaneous databases

    NextBioi 978482.

    Gene expression databases

    Genevestigatori Q03153.

    Family and domain databases

    InterProi IPR025210. ATP25_mRNA_stabil_dom.
    IPR025656. Oligomer_dom.
    [Graphical view ]
    Pfami PF13929. mRNA_stabil. 1 hit.
    PF02410. Oligomerisation. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    5. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
      Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
      J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. "ATP25, a new nuclear gene of Saccharomyces cerevisiae required for expression and assembly of the Atp9p subunit of mitochondrial ATPase."
      Zeng X., Barros M.H., Shulman T., Tzagoloff A.
      Mol. Biol. Cell 19:1366-1377(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiATP25_YEAST
    AccessioniPrimary (citable) accession number: Q03153
    Secondary accession number(s): D6VZS1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2430 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3