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Protein

Mitochondrial GTPase 1

Gene

MTG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Mitochondrial GTPase involved in assembly of the large ribosomal subunit (PubMed:12808030). Plays a role in expression of the mitochondrial translational machinery (PubMed:12808030).1 Publication

Miscellaneous

Present with 1630 molecules/cell in log phase SD medium.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei224GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi89 – 92GTPSequence analysis4
Nucleotide bindingi160 – 165GTPBy similarity6

GO - Molecular functioni

GO - Biological processi

  • mitochondrial translation Source: SGD
  • ribosome biogenesis Source: GO_Central

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-32797-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial GTPase 1
Gene namesi
Name:MTG1
Ordered Locus Names:YMR097C
ORF Names:YM6543.04C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR097C
SGDiS000004703 MTG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000203287? – 367Mitochondrial GTPase 1
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiQ03151
PaxDbiQ03151
PRIDEiQ03151

Interactioni

Protein-protein interaction databases

BioGridi35272, 201 interactors
DIPiDIP-4441N
IntActiQ03151, 8 interactors
MINTiQ03151
STRINGi4932.YMR097C

Structurei

3D structure databases

ProteinModelPortaliQ03151
SMRiQ03151
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 228CP-type GPROSITE-ProRule annotationAdd BLAST193

Sequence similaritiesi

Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00500000044923
HOGENOMiHOG000173971
InParanoidiQ03151
KOiK19828
OMAiWFPGHMT
OrthoDBiEOG092C2YFB

Family and domain databases

InterProiView protein in InterPro
IPR030378 G_CP_dom
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51721 G_CP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03151-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHINVRGTRK IISNVSSFTP RYEFPKYSMP LTDFKGHQVK ALKTFEKLLP
60 70 80 90 100
QMNMIIELRD IRAPLSTRNV VFDRIARKEH DVMKLVVYTR KDLMPGNKPY
110 120 130 140 150
IGKLKNWHEE LGEKFILLDC RNKTDVRNLL KILEWQNYEL ETNGGYLPMG
160 170 180 190 200
YRALITGMPN VGKSTLINSL RTIFHNQVNM GRKFKKVAKT GAEAGVTRAT
210 220 230 240 250
SEVIRVTSRN TESRNEIYLI DTPGIGVPGR VSDHNRMLGL ALCGSVKNNL
260 270 280 290 300
VDPIFQADYL LYLMNLQNLN DGRTELYPGS TNSPTNDIYD VLRRLQVNKS
310 320 330 340 350
QNEKSTAIEW TNKWRLHGKG IIFDPEVLLN NDEFSYKNYV NDQLEKLGDL
360
SYEGLSNKLK GNPNQVF
Length:367
Mass (Da):42,144
Last modified:November 1, 1997 - v1
Checksum:iC8FFF830B65A9E49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49807 Genomic DNA Translation: CAA89898.1
BK006946 Genomic DNA Translation: DAA09994.1
PIRiS55083
RefSeqiNP_013815.1, NM_001182597.1

Genome annotation databases

EnsemblFungiiYMR097C; YMR097C; YMR097C
GeneIDi855122
KEGGisce:YMR097C

Similar proteinsi

Entry informationi

Entry nameiMTG1_YEAST
AccessioniPrimary (citable) accession number: Q03151
Secondary accession number(s): D6VZS0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health