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Protein

MIOREX complex component 11

Gene

MRX11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-33955-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
MIOREX complex component 111 Publication
Alternative name(s):
Mitochondrial organization of gene expression protein 111 Publication
Gene namesi
Name:MRX111 Publication
Ordered Locus Names:YPL041CImported
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL041C
SGDiS000005962 MRX11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini47 – 98Cytoplasmic1 PublicationAdd BLAST52
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Topological domaini120 – 177Mitochondrial intermembrane1 PublicationAdd BLAST58
Transmembranei178 – 198HelicalSequence analysisAdd BLAST21
Topological domaini199 – 207Cytoplasmic1 Publication9

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 46MitochondrionSequence analysisAdd BLAST46
ChainiPRO_000023863847 – 207MIOREX complex component 11Add BLAST161

Proteomic databases

MaxQBiQ03079
PaxDbiQ03079
PRIDEiQ03079

Interactioni

Subunit structurei

Associates with the mitochondrial ribosome.1 Publication

Protein-protein interaction databases

BioGridi36138, 166 interactors
IntActiQ03079, 4 interactors
STRINGi4932.YPL041C

Structurei

3D structure databases

ProteinModelPortaliQ03079
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000066028
InParanoidiQ03079
OMAiYPARILF
OrthoDBiEOG092C5L8T

Family and domain databases

InterProiView protein in InterPro
IPR018811 Mrx11
PfamiView protein in Pfam
PF10306 FLILHELTA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVMNLFFRP CQLQMGSGPL ELMLKRPTQL TTFMNTRPGG STQIRFISGN
60 70 80 90 100
LDPVKRREDR LRKIFSKSRL LTRLNKNPKF SHYFDRLSEA GTVPTLTSFF
110 120 130 140 150
ILHEVTAILP LFLLWWLLYN LDLSDDFKLP NFLNGLMDSC HTAMEKFVGK
160 170 180 190 200
RYQECLNKNK LILSGTVAYV TVKLLYPVRI FISIWGAPYF GKWLLLPFQK

LKHLIKK
Length:207
Mass (Da):24,166
Last modified:November 1, 1996 - v1
Checksum:iFBB5FE92EDCA2301
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108 – 112ILPLF → NTTTV in AAT01100 (Ref. 1) Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L32174 Genomic DNA Translation: AAT01100.1
U44030 Genomic DNA Translation: AAB68179.1
AY558328 Genomic DNA Translation: AAS56654.1
BK006949 Genomic DNA Translation: DAA11388.1
PIRiS62034
RefSeqiNP_015284.1, NM_001183855.1

Genome annotation databases

EnsemblFungiiYPL041C; YPL041C; YPL041C
GeneIDi856066
KEGGisce:YPL041C

Similar proteinsi

Entry informationi

Entry nameiMRX11_YEAST
AccessioniPrimary (citable) accession number: Q03079
Secondary accession number(s): D6W3X2, Q6LE92
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health