Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

MIOREX complex component 11

Gene

MRX11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-33955-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
MIOREX complex component 111 Publication
Alternative name(s):
Mitochondrial organization of gene expression protein 111 Publication
Gene namesi
Name:MRX111 Publication
Ordered Locus Names:YPL041CImported
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL041C.
SGDiS000005962. MRX11.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini47 – 9852Cytoplasmic1 PublicationAdd
BLAST
Transmembranei99 – 11921HelicalSequence analysisAdd
BLAST
Topological domaini120 – 17758Mitochondrial intermembrane1 PublicationAdd
BLAST
Transmembranei178 – 19821HelicalSequence analysisAdd
BLAST
Topological domaini199 – 2079Cytoplasmic1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4646MitochondrionSequence analysisAdd
BLAST
Chaini47 – 207161MIOREX complex component 11PRO_0000238638Add
BLAST

Proteomic databases

MaxQBiQ03079.

Interactioni

Subunit structurei

Associates with the mitochondrial ribosome.1 Publication

Protein-protein interaction databases

BioGridi36138. 42 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ03079.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000066028.
InParanoidiQ03079.
OMAiYPARILF.
OrthoDBiEOG7F254Z.

Family and domain databases

InterProiIPR018811. Mrx11.
[Graphical view]
PfamiPF10306. FLILHELTA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVMNLFFRP CQLQMGSGPL ELMLKRPTQL TTFMNTRPGG STQIRFISGN
60 70 80 90 100
LDPVKRREDR LRKIFSKSRL LTRLNKNPKF SHYFDRLSEA GTVPTLTSFF
110 120 130 140 150
ILHEVTAILP LFLLWWLLYN LDLSDDFKLP NFLNGLMDSC HTAMEKFVGK
160 170 180 190 200
RYQECLNKNK LILSGTVAYV TVKLLYPVRI FISIWGAPYF GKWLLLPFQK

LKHLIKK
Length:207
Mass (Da):24,166
Last modified:November 1, 1996 - v1
Checksum:iFBB5FE92EDCA2301
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti108 – 1125ILPLF → NTTTV in AAT01100 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L32174 Genomic DNA. Translation: AAT01100.1.
U44030 Genomic DNA. Translation: AAB68179.1.
AY558328 Genomic DNA. Translation: AAS56654.1.
BK006949 Genomic DNA. Translation: DAA11388.1.
PIRiS62034.
RefSeqiNP_015284.1. NM_001183855.1.

Genome annotation databases

EnsemblFungiiYPL041C; YPL041C; YPL041C.
GeneIDi856066.
KEGGisce:YPL041C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L32174 Genomic DNA. Translation: AAT01100.1.
U44030 Genomic DNA. Translation: AAB68179.1.
AY558328 Genomic DNA. Translation: AAS56654.1.
BK006949 Genomic DNA. Translation: DAA11388.1.
PIRiS62034.
RefSeqiNP_015284.1. NM_001183855.1.

3D structure databases

ProteinModelPortaliQ03079.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36138. 42 interactions.

Proteomic databases

MaxQBiQ03079.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL041C; YPL041C; YPL041C.
GeneIDi856066.
KEGGisce:YPL041C.

Organism-specific databases

EuPathDBiFungiDB:YPL041C.
SGDiS000005962. MRX11.

Phylogenomic databases

HOGENOMiHOG000066028.
InParanoidiQ03079.
OMAiYPARILF.
OrthoDBiEOG7F254Z.

Enzyme and pathway databases

BioCyciYEAST:G3O-33955-MONOMER.

Miscellaneous databases

NextBioi981050.
PROiQ03079.

Family and domain databases

InterProiIPR018811. Mrx11.
[Graphical view]
PfamiPF10306. FLILHELTA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The LAF1 open reading frame encodes a second isoleucyl tRNA synthetase in the yeast Saccharomyces cerevisiae."
    Chen E., Bretscher A.P.
    Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI."
    Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M.
    , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.
    Nature 387:103-105(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  6. "Organization of mitochondrial gene expression in two distinct ribosome-containing assemblies."
    Kehrein K., Schilling R., Moller-Hergt B.V., Wurm C.A., Jakobs S., Lamkemeyer T., Langer T., Ott M.
    Cell Rep. 10:843-853(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT.

Entry informationi

Entry nameiMRX11_YEAST
AccessioniPrimary (citable) accession number: Q03079
Secondary accession number(s): D6W3X2, Q6LE92
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.