Q03079 (YP041_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized membrane protein YPL041C

Gene names

Ordered Locus Names:

YPL041C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	Uncharacterized membrane protein YPL041C		PRO_0000238638
Regions
	Topological domain	1 – 98	98	Cytoplasmic Potential
	Transmembrane	99 – 119	21	Helical; Potential
	Topological domain	120 – 177	58	Extracellular Potential
	Transmembrane	178 – 198	21	Helical; Potential
	Topological domain	199 – 207	9	Cytoplasmic Potential
Experimental info
	Sequence conflict	108 – 112	5	ILPLF → NTTTV in AAT01100. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q03079 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: FBB5FE92EDCA2301	FASTA	207	24,166
	10 20 30 40 50 60 MTVMNLFFRP CQLQMGSGPL ELMLKRPTQL TTFMNTRPGG STQIRFISGN LDPVKRREDR 70 80 90 100 110 120 LRKIFSKSRL LTRLNKNPKF SHYFDRLSEA GTVPTLTSFF ILHEVTAILP LFLLWWLLYN 130 140 150 160 170 180 LDLSDDFKLP NFLNGLMDSC HTAMEKFVGK RYQECLNKNK LILSGTVAYV TVKLLYPVRI 190 200 FISIWGAPYF GKWLLLPFQK LKHLIKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The LAF1 open reading frame encodes a second isoleucyl tRNA synthetase in the yeast Saccharomyces cerevisiae." Chen E., Bretscher A.P. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: ATCC 208353 / W303-1A.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L32174 Genomic DNA. Translation: AAT01100.1. U44030 Genomic DNA. Translation: AAB68179.1. AY558328 Genomic DNA. Translation: AAS56654.1. BK006949 Genomic DNA. Translation: DAA11388.1.
PIR	S62034.
RefSeq	NP_015284.1. NM_001183855.1.
3D structure databases
ProteinModelPortal	Q03079.
ModBase	Search...
Protein-protein interaction databases
STRING	4932.YPL041C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPL041C; YPL041C; YPL041C.
GeneID	856066.
KEGG	sce:YPL041C.
Organism-specific databases
CYGD	YPL041c.
SGD	S000005962. YPL041C.
Phylogenomic databases
eggNOG	NOG140651.
HOGENOM	HOG000066028.
OMA	RIFISIW.
OrthoDB	EOG4VQDZX.
Gene expression databases
Genevestigator	Q03079.
GermOnline	YPL041C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR018811. Uncharacterised_FLILHELTA. [Graphical view]
Pfam	PF10306. FLILHELTA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	981050.

Entry information

Entry name

YP041_YEAST

Accession

Primary (citable) accession number: Q03079
Secondary accession number(s): D6W3X2, Q6LE92

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program