ID   NSP6_ROTPY              Reviewed;          92 AA.
AC   Q03056;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   14-DEC-2022, entry version 50.
DE   RecName: Full=Non-structural protein 6;
DE            Short=NSP6;
OS   Rotavirus A (strain RVA/Pig/Mexico/YM/1983/G11P9[7]) (RV-A).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A.
OX   NCBI_TaxID=10919;
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8383837; DOI=10.1093/nar/21.4.1042;
RA   Lopez S., Arias C.F.;
RT   "Protein NS26 is highly conserved among porcine rotavirus strains.";
RL   Nucleic Acids Res. 21:1042-1042(1993).
RN   [2]
RP   INTERACTION WITH NSP5, AND SUBCELLULAR LOCATION.
RX   PubMed=10675420; DOI=10.1099/0022-1317-81-3-821;
RA   Torres-Vega M.A., Gonzalez R.A., Duarte M., Poncet D., Lopez S.,
RA   Arias C.F.;
RT   "The C-terminal domain of rotavirus NSP5 is essential for its
RT   multimerization, hyperphosphorylation and interaction with NSP6.";
RL   J. Gen. Virol. 81:821-830(2000).
CC   -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP-
CC       Rule:MF_04093, ECO:0000269|PubMed:10675420}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093,
CC       ECO:0000269|PubMed:10675420}. Host mitochondrion {ECO:0000255|HAMAP-
CC       Rule:MF_04093}. Note=Found in spherical cytoplasmic structures, called
CC       viral factories, that appear early after infection and are the site of
CC       viral replication and packaging. {ECO:0000255|HAMAP-Rule:MF_04093}.
CC   -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_04093}.
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DR   EMBL; X69486; CAA49242.1; -; Genomic_RNA.
DR   GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_04093; ROTA_NSP6; 1.
DR   InterPro; IPR006950; Rotavirus_NSP6.
DR   Pfam; PF04866; Rota_NS6; 1.
PE   1: Evidence at protein level;
KW   Host cytoplasm; Host mitochondrion.
FT   CHAIN           1..92
FT                   /note="Non-structural protein 6"
FT                   /id="PRO_0000149645"
SQ   SEQUENCE   92 AA;  10981 MW;  784F6BAF637D0A84 CRC64;
     MNRLLQRQLF LENLLVGVNS TFHQMQKHSI NTCCRSLQRI LDHLILLQTI HSPVFRLDRM
     QLRQMQTLAC LWIHRRNHDL QVTLGAIKWI SP
//