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Q03056 (NSP6_ROTPY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-structural protein 6

Short name=NSP6
OrganismRotavirus A (strain Pig/Mexico/YM/1983 G11-P9[7]-I5-R1-C1-M1-A8-N1-T1-E1-H1) (RV-A)
Taxonomic identifier10919 [NCBI]
Taxonomic lineageVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostSus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length92 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with NSP5. Ref.2

Subcellular location

Host cytoplasm. Note: Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging. Ref.2

Sequence similarities

Belongs to the rotavirus A NSP6 family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9292Non-structural protein 6
PRO_0000149645

Sequences

Sequence LengthMass (Da)Tools
Q03056 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 784F6BAF637D0A84

FASTA9210,981
        10         20         30         40         50         60 
MNRLLQRQLF LENLLVGVNS TFHQMQKHSI NTCCRSLQRI LDHLILLQTI HSPVFRLDRM 

        70         80         90 
QLRQMQTLAC LWIHRRNHDL QVTLGAIKWI SP 

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References

[1]"Protein NS26 is highly conserved among porcine rotavirus strains."
Lopez S., Arias C.F.
Nucleic Acids Res. 21:1042-1042(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"The C-terminal domain of rotavirus NSP5 is essential for its multimerization, hyperphosphorylation and interaction with NSP6."
Torres-Vega M.A., Gonzalez R.A., Duarte M., Poncet D., Lopez S., Arias C.F.
J. Gen. Virol. 81:821-830(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH NSP5, SUBCELLULAR LOCATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X69486 Genomic RNA. Translation: CAA49242.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR006950. Rotavirus_NSP6.
[Graphical view]
PfamPF04866. Rota_NS6. 1 hit.
[Graphical view]
ProDomPD008065. Rota_NS6. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNSP6_ROTPY
AccessionPrimary (citable) accession number: Q03056
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: April 3, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families