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Protein

Alkaline protease secretion ATP-binding protein AprD

Gene

aprD

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the secretion of alkaline protease.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi366 – 373ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • protein secretion by the type I secretion system Source: InterPro
  • secretion Source: PseudoCAP

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-1271-MONOMER

Protein family/group databases

TCDBi3.A.1.110.4 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline protease secretion ATP-binding protein AprD
Gene namesi
Name:aprD
Ordered Locus Names:PA1246
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA1246

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei60 – 80HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei134 – 154HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei156 – 176HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei248 – 266HelicalPROSITE-ProRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000919331 – 593Alkaline protease secretion ATP-binding protein AprDAdd BLAST593

Proteomic databases

PaxDbiQ03024
PRIDEiQ03024

Interactioni

Protein-protein interaction databases

STRINGi208964.PA1246

Structurei

3D structure databases

ProteinModelPortaliQ03024
SMRiQ03024
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 301ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST279
Domaini332 – 567ABC transporterPROSITE-ProRule annotationAdd BLAST236

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108JJ6 Bacteria
COG4618 LUCA
HOGENOMiHOG000101575
InParanoidiQ03024
KOiK12536
OMAiSIMMGRA
PhylomeDBiQ03024

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR010128 ATPase_T1SS_PrtD
IPR027417 P-loop_NTPase
PANTHERiPTHR24222:SF0 PTHR24222:SF0, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
TIGRFAMsiTIGR01842 type_I_sec_PrtD, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q03024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLGSSVTN EIKQALAASR GALRSVAAFS GVINLLMLVP SLYMLQVYDR
60 70 80 90 100
VLSSANEVTL LMLTLMALGV FVFMGALEAL RSFVLVRVSE RFDGQLHGRI
110 120 130 140 150
YAAAFERNLR AGGQEASQAL HDLTTLRQFI TGQALFAFFD APWFPVYLLV
160 170 180 190 200
IFLFDPWLGL LSLVGALALM ALAWFNERAT RAPLAKAGEL SIKSGQLASN
210 220 230 240 250
NLRNAEVIEA MGMLGSMRGR WERLHQAFLD QQSLASERAA RINALSKYLR
260 270 280 290 300
IALQSLVLGL GAWLAVEGRI TPGMMIAGSI LMGRALGPID QLIGVWKQWG
310 320 330 340 350
AARDAYRRLS GLLDEFPARE RRMELPEPRG HLLLESLDAA PPGSEARTLR
360 370 380 390 400
GLTLAIPAGS VVGVIGPSGS GKSSLARVVL GIWPTLHGSV RLDGAEIRQY
410 420 430 440 450
ERETLGPRIG YLPQDIELFA GTVAENIARF GEVQADKVVE AARLAGVHEL
460 470 480 490 500
VLRLPQGYDT VLGVGGAGLS GGQRQRIALA RALYGAPTLV VLDEPNSNLD
510 520 530 540 550
DSGEQALLAA IQALKARGCT VLLITHRAGV LGCADRLLAL NAGQLHLYGE
560 570 580 590
RDQVLAALNN QRAASASQQR ADYRVAGYGA PQVVAAPRQG GVE
Length:593
Mass (Da):63,671
Last modified:October 1, 1993 - v1
Checksum:iCA3A817FBCC27318
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64558 Genomic DNA Translation: CAA45855.1
AE004091 Genomic DNA Translation: AAG04635.1
PIRiS26696
RefSeqiNP_249937.1, NC_002516.2
WP_003082539.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG04635; AAG04635; PA1246
GeneIDi881263
KEGGipae:PA1246
PATRICifig|208964.12.peg.1293

Similar proteinsi

Entry informationi

Entry nameiAPRD_PSEAE
AccessioniPrimary (citable) accession number: Q03024
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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