SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q03021

- RIO1_THEAC

UniProt

Q03021 - RIO1_THEAC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
RIO-type serine/threonine-protein kinase Rio1
Gene
rio1, Ta0396
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ATP By similarity
Active sitei124 – 1241Proton acceptor By similarity
Metal bindingi129 – 1291Magnesium By similarity
Binding sitei129 – 1291ATP By similarity
Metal bindingi140 – 1401Magnesium By similarity
Binding sitei140 – 1401ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
  4. protein tyrosine kinase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RIO-type serine/threonine-protein kinase Rio1 (EC:2.7.11.1)
    Gene namesi
    Name:rio1
    Ordered Locus Names:Ta0396
    OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
    Taxonomic identifieri273075 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
    ProteomesiUP000001024: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 186186RIO-type serine/threonine-protein kinase Rio1
    PRO_0000213536Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273075.Ta0396m.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03021.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1718.
    KOiK07178.
    OMAiERIHSAS.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR018934. RIO-like_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view]
    PfamiPF01163. RIO1. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01245. RIO1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q03021-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVFRAVSGKK FVAVKIFKMS TLKFMSIRKY IEGDQRFSKI RIDRNDIVPV    50
    WVRKEYTNLM ALENAHVPAP KPIGFFKNIL VMSYIGTKSG PAPQLKDVEI 100
    DEGIYDQVID GMRRMYANRI VHADLSEYNM LFHRKVYFID LAQAVDMDHP 150
    MAAEFLERDI VNVSNFFQKH GIETDPDKIR EYIKKK 186
    Length:186
    Mass (Da):21,739
    Last modified:June 1, 1994 - v1
    Checksum:i64E2FC7F0AF6C18A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68198 Genomic DNA. Translation: CAA48285.1.
    AL445064 Genomic DNA. Translation: CAC11539.1.
    PIRiS26727.
    RefSeqiNP_393875.1. NC_002578.1.

    Genome annotation databases

    EnsemblBacteriaiCAC11539; CAC11539; CAC11539.
    GeneIDi1457005.
    KEGGitac:Ta0396m.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68198 Genomic DNA. Translation: CAA48285.1 .
    AL445064 Genomic DNA. Translation: CAC11539.1 .
    PIRi S26727.
    RefSeqi NP_393875.1. NC_002578.1.

    3D structure databases

    ProteinModelPortali Q03021.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 273075.Ta0396m.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC11539 ; CAC11539 ; CAC11539 .
    GeneIDi 1457005.
    KEGGi tac:Ta0396m.

    Phylogenomic databases

    eggNOGi COG1718.
    KOi K07178.
    OMAi ERIHSAS.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR018934. RIO-like_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view ]
    Pfami PF01163. RIO1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01245. RIO1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "Nucleotide sequence of the genes encoding the subunits H, B, A' and A'' of the DNA-dependent RNA polymerase and the initiator tRNA from Thermoplasma acidophilum."
      Klenk H.-P., Renner O., Schwass V., Zillig W.
      Nucleic Acids Res. 20:5226-5226(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.
    2. "The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
      Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
      Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

    Entry informationi

    Entry nameiRIO1_THEAC
    AccessioniPrimary (citable) accession number: Q03021
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: May 14, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi