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Q03021

- RIO1_THEAC

UniProt

Q03021 - RIO1_THEAC

Protein

RIO-type serine/threonine-protein kinase Rio1

Gene

rio1

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ATPBy similarity
    Active sitei124 – 1241Proton acceptorBy similarity
    Metal bindingi129 – 1291MagnesiumBy similarity
    Binding sitei129 – 1291ATPBy similarity
    Metal bindingi140 – 1401MagnesiumBy similarity
    Binding sitei140 – 1401ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. protein serine/threonine kinase activity Source: UniProtKB-KW
    4. protein tyrosine kinase activity Source: InterPro

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RIO-type serine/threonine-protein kinase Rio1 (EC:2.7.11.1)
    Gene namesi
    Name:rio1
    Ordered Locus Names:Ta0396
    OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
    Taxonomic identifieri273075 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
    ProteomesiUP000001024: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 186186RIO-type serine/threonine-protein kinase Rio1PRO_0000213536Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273075.Ta0396m.

    Structurei

    3D structure databases

    ProteinModelPortaliQ03021.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1718.
    KOiK07178.
    OMAiERIHSAS.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR018934. RIO-like_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view]
    PfamiPF01163. RIO1. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01245. RIO1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q03021-1 [UniParc]FASTAAdd to Basket

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    MVFRAVSGKK FVAVKIFKMS TLKFMSIRKY IEGDQRFSKI RIDRNDIVPV    50
    WVRKEYTNLM ALENAHVPAP KPIGFFKNIL VMSYIGTKSG PAPQLKDVEI 100
    DEGIYDQVID GMRRMYANRI VHADLSEYNM LFHRKVYFID LAQAVDMDHP 150
    MAAEFLERDI VNVSNFFQKH GIETDPDKIR EYIKKK 186
    Length:186
    Mass (Da):21,739
    Last modified:June 1, 1994 - v1
    Checksum:i64E2FC7F0AF6C18A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68198 Genomic DNA. Translation: CAA48285.1.
    AL445064 Genomic DNA. Translation: CAC11539.1.
    PIRiS26727.
    RefSeqiNP_393875.1. NC_002578.1.

    Genome annotation databases

    EnsemblBacteriaiCAC11539; CAC11539; CAC11539.
    GeneIDi1457005.
    KEGGitac:Ta0396m.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68198 Genomic DNA. Translation: CAA48285.1 .
    AL445064 Genomic DNA. Translation: CAC11539.1 .
    PIRi S26727.
    RefSeqi NP_393875.1. NC_002578.1.

    3D structure databases

    ProteinModelPortali Q03021.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273075.Ta0396m.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC11539 ; CAC11539 ; CAC11539 .
    GeneIDi 1457005.
    KEGGi tac:Ta0396m.

    Phylogenomic databases

    eggNOGi COG1718.
    KOi K07178.
    OMAi ERIHSAS.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR018934. RIO-like_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view ]
    Pfami PF01163. RIO1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01245. RIO1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the genes encoding the subunits H, B, A' and A'' of the DNA-dependent RNA polymerase and the initiator tRNA from Thermoplasma acidophilum."
      Klenk H.-P., Renner O., Schwass V., Zillig W.
      Nucleic Acids Res. 20:5226-5226(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.
    2. "The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
      Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
      Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

    Entry informationi

    Entry nameiRIO1_THEAC
    AccessioniPrimary (citable) accession number: Q03021
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3