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Protein

RIO-type serine/threonine-protein kinase Rio1

Gene

rio1

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity).By similarity

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15ATPBy similarity1
Active sitei124Proton acceptorBy similarity1
Metal bindingi129MagnesiumBy similarity1
Active sitei1404-aspartylphosphate intermediateBy similarity1
Metal bindingi140MagnesiumBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Kinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RIO-type serine/threonine-protein kinase Rio1 (EC:2.7.11.1, EC:3.6.3.-)
Gene namesi
Name:rio1
Ordered Locus Names:Ta0396
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002135361 – 186RIO-type serine/threonine-protein kinase Rio1Add BLAST186

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta0396m

Structurei

3D structure databases

ProteinModelPortaliQ03021
SMRiQ03021
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01180 Archaea
COG1718 LUCA
KOiK07178
OMAiPYGFYRN
OrthoDBiPOG093Z07MT

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000687 RIO_kinase
IPR018935 RIO_kinase_CS
IPR008266 Tyr_kinase_AS
SMARTiView protein in SMART
SM00090 RIO, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS01245 RIO1, 1 hit

Sequencei

Sequence statusi: Complete.

Q03021-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFRAVSGKK FVAVKIFKMS TLKFMSIRKY IEGDQRFSKI RIDRNDIVPV
60 70 80 90 100
WVRKEYTNLM ALENAHVPAP KPIGFFKNIL VMSYIGTKSG PAPQLKDVEI
110 120 130 140 150
DEGIYDQVID GMRRMYANRI VHADLSEYNM LFHRKVYFID LAQAVDMDHP
160 170 180
MAAEFLERDI VNVSNFFQKH GIETDPDKIR EYIKKK
Length:186
Mass (Da):21,739
Last modified:June 1, 1994 - v1
Checksum:i64E2FC7F0AF6C18A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68198 Genomic DNA Translation: CAA48285.1
AL445064 Genomic DNA Translation: CAC11539.1
PIRiS26727

Genome annotation databases

EnsemblBacteriaiCAC11539; CAC11539; CAC11539
KEGGitac:Ta0396

Entry informationi

Entry nameiRIO1_THEAC
AccessioniPrimary (citable) accession number: Q03021
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health