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Protein

Uronate isomerase

Gene

uxaC

Organism
Lactococcus lactis subsp. cremoris (strain SK11)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:LACR_1742
OrganismiLactococcus lactis subsp. cremoris (strain SK11)
Taxonomic identifieri272622 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000000240 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000447711 – 472Uronate isomeraseAdd BLAST472

Structurei

3D structure databases

ProteinModelPortaliQ02XT4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q02XT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFLSEDFLL NNENAKLLFH KHAEKMPIID YHCHLEQEEI YENKKYENLT
60 70 80 90 100
QIWLGGDHYK WRLLRANGIP EKLITGDGDD YEKFLAFAKT LEKSLGNPIY
110 120 130 140 150
EWTHLELKRF FHIDKLISSE TAKEIWDEAN QMLATDDFRP RALIKNSNVK
160 170 180 190 200
VVCTTDAPVS KLSYHKSLAK EEKDFKVLPA LRPDHLISIT DGHFAEYLTE
210 220 230 240 250
LSAVSGIKIK DFKTMIKALE QRFEFFTSLG GRLSDHSLST YTFAETDDVD
260 270 280 290 300
LDSIIQRAKE KQTLTDLEYN QYITALILEI MKLNKKFDWT MQLHVNVNRS
310 320 330 340 350
INGPALRKIG ENTGFDSMGT QANISEELTK LFSKAAELEI IPKTILYSLN
360 370 380 390 400
QNDWLELATL IGCFQGEGVQ QLQLGAGWWF NDTAKGMEKQ LEIFASQSLL
410 420 430 440 450
PNFVGMLTDS RSFLSYPRHE YFRRVLCNFV GQLIESGRIP DDEALVGKMI
460 470
EDISYNNVHD YFGFFKNEDS KQ
Length:472
Mass (Da):54,496
Last modified:November 14, 2006 - v1
Checksum:iFA0582815FF6557F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000425 Genomic DNA. Translation: ABJ73238.1.
RefSeqiWP_011676671.1. NC_008527.1.

Genome annotation databases

EnsemblBacteriaiABJ73238; ABJ73238; LACR_1742.
KEGGillc:LACR_1742.
PATRICi22290355. VBILacLac38071_1923.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000425 Genomic DNA. Translation: ABJ73238.1.
RefSeqiWP_011676671.1. NC_008527.1.

3D structure databases

ProteinModelPortaliQ02XT4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ73238; ABJ73238; LACR_1742.
KEGGillc:LACR_1742.
PATRICi22290355. VBILacLac38071_1923.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_LACLS
AccessioniPrimary (citable) accession number: Q02XT4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: November 2, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.