Q02XT1 (Q02XT1_LACLS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannonate dehydratase HAMAP MF_00106
EC=4.2.1.8 HAMAP MF_00106

Alternative name(s):
D-mannonate hydrolase HAMAP MF_00106

Gene names

Name:	uxuA HAMAP MF_00106
Ordered Locus Names:	LACR_1745

Organism

Lactococcus lactis subsp. cremoris (strain SK11) [Complete proteome] [HAMAP] EMBL ABJ73241.1

Taxonomic identifier

272622 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family. HAMAP MF_00106

Ontologies

Keywords
Molecular function	Lyase HAMAP MF_00106 EMBL ABJ73241.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q02XT1 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 5E50625ACA1BCB8B	FASTA	354	40,154
	10 20 30 40 50 60 MRWFGSNADK VELSEIAQVP GVKGVVGMIM DIPAGEVWPK ERIKALKEEI EAAGLSLKVI 70 80 90 100 110 120 ESVNIHDDIK IGLPTRDKYI ENYKETIRNL AEFGIEVICY NFMPVFDWLK SDLDYRLADN 130 140 150 160 170 180 SQTIAFVAGD IPENPQEIID RVQAADGGFS LPGWEPERLS EVKDLFEAYK NVDEHKLREN 190 200 210 220 230 240 FAYFLKAIIP TCEEVGIKMA VHPDDPPYPM FGLPRVVKNR EDLDWICNVV DSPSNAITLC 250 260 270 280 290 300 TGSIAEDPAN NVDEIMAEFI KRDRIPFAHV RNIKFLPSGE KDFYEAPHMS EHGSLDMYKI 310 320 330 340 350 LKAMYDNGFD GYIRPDHGRM IWGETGRPGY GLYDRALGAS YLNGLWEALE KNNQ

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000425 Genomic DNA. Translation: ABJ73241.1.
RefSeq	YP_809685.1. NC_008527.1.
3D structure databases
ProteinModelPortal	Q02XT1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q02XT1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4433527.
GenomeReviews	Gene locus LACR_1745 in contig CP000425_GR.
KEGG	llc:LACR_1745.
PATRIC	22290361. VBILacLac38071_1926.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1312.
HOGENOM	HBG585927.
OMA	DIKLGKP.
ProtClustDB	PRK03906.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KO	K01686.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q02XT1_LACLS

Accession

Primary (citable) accession number: Q02XT1

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)