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Q02VW5

- G6PI_LACLS

UniProt

Q02VW5 - G6PI_LACLS

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, LACR_2470
Organism
Lactococcus lactis subsp. cremoris (strain SK11)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei290 – 2901Proton donor By similarity
Active sitei311 – 3111 By similarity
Active sitei425 – 4251 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLLAC272622:GJUG-2470-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:LACR_2470
OrganismiLactococcus lactis subsp. cremoris (strain SK11)
Taxonomic identifieri272622 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000000240: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448Glucose-6-phosphate isomeraseUniRule annotationPRO_1000013981Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272622.LACR_2470.

Structurei

3D structure databases

ProteinModelPortaliQ02VW5.
SMRiQ02VW5. Positions 3-448.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiKNMTHIT.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q02VW5-1 [UniParc]FASTAAdd to Basket

« Hide

MAHIKFDYSK LTPFVAENEL YEIQWQIDGA AKLLHEGKGA GSDYIGWLDL    50
PEDYDKEEFA RIQKAAKKIK SDSEVLIVIG IGGSYLGARA AIDFLSNSFV 100
NLQTAEERKA PRILYAGNSI SSSYLADLVD YVADKDFSVN VISKSGTTTE 150
PAIAFRVFEE MLVKKYGREE ANKRIYATTD KEKGAVKVNA DANNWETFVV 200
PDSVGGRFSV LTAVGLLPIA ASGADITALM EGANAARKEY TSTNVHENDA 250
YAYAALRNIL YRKGKFSEIL INYEPSLQYF SEWWKQLAGE SEGKDQKGIY 300
PTSANFSTDL HSLGQWIQEG TRTVFETAIR IEKPRKNINI PELDADLDGL 350
GYLQGKDVDF VNKKAADGVL LAHTDGNVPN MIVTLPEQDE FTLGYAIYFF 400
ELAIGVSGYL NGINPFNQPG VEAYKKNMFA LLGKPGFEEL SKELNDRL 448
Length:448
Mass (Da):49,643
Last modified:November 14, 2006 - v1
Checksum:iBE0823F3D31B8309
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000425 Genomic DNA. Translation: ABJ73907.1.
RefSeqiYP_812020.1. NC_008527.1.

Genome annotation databases

EnsemblBacteriaiABJ73907; ABJ73907; LACR_2470.
GeneIDi4432905.
KEGGillc:LACR_2470.
PATRICi22291825. VBILacLac38071_2638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000425 Genomic DNA. Translation: ABJ73907.1 .
RefSeqi YP_812020.1. NC_008527.1.

3D structure databases

ProteinModelPortali Q02VW5.
SMRi Q02VW5. Positions 3-448.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272622.LACR_2470.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ73907 ; ABJ73907 ; LACR_2470 .
GeneIDi 4432905.
KEGGi llc:LACR_2470.
PATRICi 22291825. VBILacLac38071_2638.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi KNMTHIT.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci LLAC272622:GJUG-2470-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK11.

Entry informationi

Entry nameiG6PI_LACLS
AccessioniPrimary (citable) accession number: Q02VW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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