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Reviewed, UniProtKB/Swiss-Prot Q02V57 (HEM6_PSEAB)

Last modified June 16, 2009. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: PA14_00280
OrganismPseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP]
Taxonomic identifier208963 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

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Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Coproporphyrinogen-III oxidase, aerobic
PRO_1000019484

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Sequences

Sequence LengthMass (Da)Tools
Q02V57-1 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 240BD06FEA37EAE3

FASTA30534,806
        10         20         30         40         50         60 
MTDRIAAVKT YLLDLQDRIC AALEAEDGKA RFAEDAWERP AGGGGRTRVI GDGALIEKGG 

        70         80         90        100        110        120 
VNFSHVFGDS LPPSASAHRP ELAGRGFQAL GVSLVIHPEN PHVPTSHANV RFFCAEKEGE 

       130        140        150        160        170        180 
EPVWWFGGGF DLTPYYAHEE DCVHWHRVAR DACAPFGADV YPRYKEWCDR YFHLKHRNEP 

       190        200        210        220        230        240 
RGIGGLFFDD LNQWDFDTCF AFIRAIGDAY IDAYLPIVQR RKHTPFDERQ REFQAYRRGR 

       250        260        270        280        290        300 
YVEFNLVFDR GTLFGLQSGG RTESILMSLP PQVRWGYDWK PEPGSEEARL TEYFLADRDW 


LAGQP

« Hide

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References

[1]"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial."
Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.
Genome Biol. 7:RESEARCH90.1-RESEARCH90.14(2006) [PubMed: 17038190] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000438 Genomic DNA. Translation: ABJ14980.1.
RefSeqYP_788179.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4384742.
GenomeReviewsGene locus PA14_00280 in contig CP000438_GR.
KEGGpau:PA14_00280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQ02V57. VKAYLLD.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_PSEAB
AccessionPrimary (citable) accession number: Q02V57
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents