SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q02U31

- TRMB_PSEAB

UniProt

Q02U31 - TRMB_PSEAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, PA14_05000
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei74 – 741S-adenosyl-L-methionine By similarity
Binding sitei99 – 991S-adenosyl-L-methionine By similarity
Binding sitei126 – 1261S-adenosyl-L-methionine By similarity
Active sitei149 – 1491 By similarity
Binding sitei149 – 1491S-adenosyl-L-methionine By similarity
Binding sitei153 – 1531Substrate By similarity
Binding sitei185 – 1851Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPAER208963:GI5K-401-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:PA14_05000
OrganismiPseudomonas aeruginosa (strain UCBPP-PA14)
Taxonomic identifieri208963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000653: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000288203Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208963.PA14_05000.

Structurei

3D structure databases

ProteinModelPortaliQ02U31.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni222 – 2254Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q02U31-1 [UniParc]FASTAAdd to Basket

« Hide

MSDTPQSPAQ GSLAEHDEAR PMRTVKSFVM RAGRMTEGQQ RGLDLGWPKF    50
GLELSDEVQD FDAIFGRQAP RTFEIGFGMG HSTLEMAAAA PDIDFIGVEV 100
HKPGVGALLN GLLTQGLGNV RVYSCDALEV LRHCVADASL DRLLLFFPDP 150
WHKKRHHKRR IVQPEFAELV RRKLKVGGVL HMATDWEPYA EHMLDVMSAA 200
PGYRNQAEDG RFVARPQERP VTKFERRGER LGHGVWDLKF ERID 244
Length:244
Mass (Da):27,525
Last modified:May 29, 2007 - v2
Checksum:iE7DFE8529BE6FF56
GO

Sequence cautioni

The sequence ABJ15348.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000438 Genomic DNA. Translation: ABJ15348.1. Different initiation.
RefSeqiYP_788555.1. NC_008463.1.

Genome annotation databases

EnsemblBacteriaiABJ15348; ABJ15348; PA14_05000.
GeneIDi4383771.
KEGGipau:PA14_05000.
PATRICi19846854. VBIPseAer79785_0411.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000438 Genomic DNA. Translation: ABJ15348.1 . Different initiation.
RefSeqi YP_788555.1. NC_008463.1.

3D structure databases

ProteinModelPortali Q02U31.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208963.PA14_05000.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ15348 ; ABJ15348 ; PA14_05000 .
GeneIDi 4383771.
KEGGi pau:PA14_05000.
PATRICi 19846854. VBIPseAer79785_0411.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci PAER208963:GI5K-401-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCBPP-PA14.

Entry informationi

Entry nameiTRMB_PSEAB
AccessioniPrimary (citable) accession number: Q02U31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 11, 2014
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi