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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:PA14_07700
OrganismiPseudomonas aeruginosa (strain UCBPP-PA14)
Taxonomic identifieri208963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000653 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120761 – 283Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST283

Structurei

3D structure databases

ProteinModelPortaliQ02TH3
SMRiQ02TH3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q02TH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVYAVGDLQ GCLDPLKCLL ERVAFDPAKD RLWLVGDLVN RGPQSLETLR
60 70 80 90 100
FLYAMRESVV SVLGNHDLHL LAVAHKSERL KKSDTLREIL EAPDREPLLD
110 120 130 140 150
WLRRLPLLHY DEQRKVALVH AGIPPQWSLE KARLRAAEVE QALRDDQRLP
160 170 180 190 200
LFLDGMYGNE PAKWDKKLHG IDRLRVITNY FTRMRFCTED GKLDLKSKEG
210 220 230 240 250
LDTAPPGYAP WFSFPSRKTR GEKIIFGHWA ALEGHCDEPG LFALDTGCVW
260 270 280
GARMTLLNVD SGERLSCDCA EQRAPARPAA TPA
Length:283
Mass (Da):32,019
Last modified:November 14, 2006 - v1
Checksum:iB7F21AE147168459
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000438 Genomic DNA Translation: ABJ15554.1
RefSeqiWP_003113213.1, NC_008463.1

Genome annotation databases

EnsemblBacteriaiABJ15554; ABJ15554; PA14_07700
KEGGipau:PA14_07700

Similar proteinsi

Entry informationi

Entry nameiAPAH_PSEAB
AccessioniPrimary (citable) accession number: Q02TH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health