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Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAER208963:GI5K-1184-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HscA homologUniRule annotation
Gene namesi
Name:hscAUniRule annotation
Ordered Locus Names:PA14_14780
OrganismiPseudomonas aeruginosa (strain UCBPP-PA14)
Taxonomic identifieri208963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000653 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 619619Chaperone protein HscA homologPRO_1000044870Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ02RW4.
SMRiQ02RW4. Positions 389-616.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q02RW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLQIAEPG QSPKPHERRL AVGIDLGTTN SLVAAVRSGV AEPLPDAQGR
60 70 80 90 100
LILPSAVRYH AERAEVGESA RAAAAKDPFN TIISVKRLMG RGLEDVKQLG
110 120 130 140 150
EQLPYRFRQG ESHMPFIETV QGLKSPVEVS ADILRELRQR AETTLGGELV
160 170 180 190 200
GAVITVPAYF DDAQRQATKD AARLAGLNVL RLLNEPTAAA VAYGLDKGAE
210 220 230 240 250
GLVAIYDLGG GTFDISILRL TRGVFEVLAT GGDTALGGDD FDHAIAGWVI
260 270 280 290 300
EQAGLSADLD PGSQRQLLQI ACAAKERLTD EASVRVAYGD WSGELSRATL
310 320 330 340 350
DELIEPFVAR SLKSCRRAVR DSGVDLEEIR SVVMVGGSTR VPRVRTAVGE
360 370 380 390 400
LFGCEPLTDI DPDQVVAIGA AIQADALAGN KRGEELLLLD VIPLSLGLET
410 420 430 440 450
MGGLMEKVIP RNTTIPVARA QEFTTYKDGQ TAMMIHVLQG ERELVKDCRS
460 470 480 490 500
LARFELRGIP PMVAGAAKIR VTFQVDADGL LGVSARELSS GVEASIQVKP
510 520 530 540 550
SYGLTDGEIA RMLKDSFDYA GDDKAARALR EQQVEAQRLL EAVQSALDVD
560 570 580 590 600
GERLLDEEER LAIAAQMDTL RELAGGSDTA AIENQIKRLS QVTDAFAARR
610
MDATVKAALS GRRLNEIEE
Length:619
Mass (Da):66,460
Last modified:November 14, 2006 - v1
Checksum:i9F1FE80E16F489B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000438 Genomic DNA. Translation: ABJ13071.1.
RefSeqiWP_003092822.1. NC_008463.1.

Genome annotation databases

EnsemblBacteriaiABJ13071; ABJ13071; PA14_14780.
KEGGipau:PA14_14780.
PATRICi19848451. VBIPseAer79785_1197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000438 Genomic DNA. Translation: ABJ13071.1.
RefSeqiWP_003092822.1. NC_008463.1.

3D structure databases

ProteinModelPortaliQ02RW4.
SMRiQ02RW4. Positions 389-616.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ13071; ABJ13071; PA14_14780.
KEGGipau:PA14_14780.
PATRICi19848451. VBIPseAer79785_1197.

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.

Enzyme and pathway databases

BioCyciPAER208963:GI5K-1184-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSCA_PSEAB
AccessioniPrimary (citable) accession number: Q02RW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.