Q02RD0 (GLND_PSEAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	PA14_17040

Organism

Pseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP]

Taxonomic identifier

208963 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa group › Pseudomonas aeruginosa

Protein attributes

Sequence length	900 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 900	900	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000022350

Sequences

	Sequence		Length	Mass (Da)
	Q02RD0 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 3CD9887250E5E897	FASTA	900	103,418
	10 20 30 40 50 60 MPQVDPELFD RGQFQAELAL KSSPIAAFKK AIRQFREVLD NRFNSGRDIR RLIEDRAWCV 70 80 90 100 110 120 DQILQQAWQR FDWGDDADIT LVAVGGYGRG ELHPYSDVDL LILLDSEDQE SFREPIEGFL 130 140 150 160 170 180 TLLWDIGLEV GQSVRSVQQC AEEARADLTV ITTLMECRTI CGPDSLRQRM LQVTGSAHMW 190 200 210 220 230 240 PSKEFFLAKR HEQQRRHAKY NDTEYNLEPN VKGSPGGLRD IQTILWMARR QFGSLNLHAL 250 260 270 280 290 300 VREGFLVESE CSMLASSQEF LWRVRYALHM LAGRAEDRLL FDHQRSIARL FGYEDNDVKL 310 320 330 340 350 360 AVERFMQKYY RVVMAISELN DLIIQHFEEV ILPCEQPVQI QPLNSRFQLR DGYIEVTHPN 370 380 390 400 410 420 VFKRTPFALL EIFVLMAQHP EIKGVRADTI RLLRDSRHLI DDEFRHDIRN TSLFIELFKS 430 440 450 460 470 480 SQGIHRNLRR MNRYGILGRY LPEFGHIIGQ MQHDLFHIYT VDAHTLNLIK HLRKLNRPEM 490 500 510 520 530 540 AEKYPLASKI IDRLPKPELI YIAGLYHDIA KGRGGDHSEL GAVDAEAFCQ SHQLPPWDTQ 550 560 570 580 590 600 LVSWLVQNHL VMSTTAQRKD LSDPQVIFDF AQLVGDQTHL DYLYVLTVAD INATNPTLWN 610 620 630 640 650 660 SWRASLLRQL YTETKRALRR GLENPVDREE QIRQTQTAAL DQLVRNGIDQ DDAEQLWSQL 670 680 690 700 710 720 GDDYFLRHTA GDVAWHTEAI LQHPDDGTPL VLIKETTQRE FESGSQIFIY AADQHDFFAV 730 740 750 760 770 780 TVAAMDQLNL SIQDARIITS TSQFTLDTYI VLDADGDSIG NNPERIAEIR EGLIDALKNP 790 800 810 820 830 840 DDYPTIIQRR VPRQLKHFAF APQVTISTDA LRQVSVLEVI APDRPGLLAR IGGIFLDFDL 850 860 870 880 890 900 SVQNAKIATL GERVEDVFYI TDARNQPLAD PDLCKRLQAA LVEQLSQDNG RDTLPTRINF

References

[1]

"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial." Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M. Genome Biol. 7:R90.1-R90.14(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UCBPP-PA14.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000438 Genomic DNA. Translation: ABJ12891.1.
RefSeq	YP_789506.1. NC_008463.1.
3D structure databases
ProteinModelPortal	Q02RD0.
ModBase	Search...
Protein-protein interaction databases
STRING	208963.PA14_17040.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ12891; ABJ12891; PA14_17040.
GeneID	4383349.
KEGG	pau:PA14_17040.
PATRIC	19848829. VBIPseAer79785_1386.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK00275.
Enzyme and pathway databases
BioCyc	PAER208963:GI5K-1435-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_PSEAB

Accession

Primary (citable) accession number: Q02RD0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program