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Q02LD4 (PQQC_PSEAB) Reviewed, UniProtKB/Swiss-Prot

Last modified August 10, 2010. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
Customize displayNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase
EC=1.3.3.11
Alternative name(s):
Coenzyme PQQ synthesis protein C
Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name:pqqC
Ordered Locus Names:PA14_38800
OrganismPseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP]
Taxonomic identifier208963 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

pyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 250250Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_1000061672

Sequences

Sequence LengthMass (Da)Tools
Q02LD4-1 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 6245E87D0C200E46

FASTA25029,449
        10         20         30         40         50         60 
MSRAAMDRAE FERALRDKGR YYHIHHPFHV AMYEGRASRE QIQGWVANRF YYQVNIPLKD 

        70         80         90        100        110        120 
AAILANCPDR EVRREWIQRI LDHDGAPGEA GGIEAWLRLA EAVGLEREQV LSEERVLPGV 

       130        140        150        160        170        180 
RFAVDAYVNF ARRASWQEAA SSSLTELFAP QIHQSRLDSW PRHYPWIEAA GYEYFRSRLA 

       190        200        210        220        230        240 
QARRDVEHGL RITLEHYRTR EAQERMLDIL QFKLDVLWSM LDAMSMAYEL ERPPYHTVTR 

       250 
ERVWHRGLAS

« Hide

References

[1]"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial."
Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.
Genome Biol. 7:R90.1-R90.14(2006) [PubMed: 17038190] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000438 Genomic DNA. Translation: ABJ11174.1.
RefSeqYP_791252.1.

3D structure databases

ProteinModelPortalQ02LD4.
SMRQ02LD4. Positions 11-245.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ02LD4.

Genome annotation databases

GeneID4380272.
GenomeReviewsGene locus PA14_38800 in contig CP000438_GR.
KEGGpau:PA14_38800.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG5424.
HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Enzyme and pathway databases

BioCycPAER208963:PA14_38800-MONOMER.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synth_PqqC.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePQQC_PSEAB
AccessionPrimary (citable) accession number: Q02LD4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 14, 2006
Last modified: August 10, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents