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Q02KC3 (GLSA_PSEAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:PA14_43320
OrganismPseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP]
Taxonomic identifier208963 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Glutaminase HAMAP-Rule MF_00313
PRO_1000048341

Sites

Binding site611Substrate By similarity
Binding site1111Substrate By similarity
Binding site1551Substrate By similarity
Binding site1621Substrate By similarity
Binding site1861Substrate By similarity
Binding site2381Substrate By similarity
Binding site2561Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q02KC3 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: B8AE7C2389E3B2E4

FASTA30233,012
        10         20         30         40         50         60 
MQQLLNEILD EVRPLIGRGK VADYIPALAG VEPNQLGIAV YSRDGELFHA GDALRPFSIQ 

        70         80         90        100        110        120 
SISKVFSLVQ AIQHSGEDIW QRLGHEPSGQ PFNSLVQLEF ERGKPRNPFI NAGALVICDI 

       130        140        150        160        170        180 
NQSRFAAPAQ SMRDFVRRLC GNPEVVSDSV VARSEYQHRS RNAAAAYLMK SFGNFHNDVE 

       190        200        210        220        230        240 
AVLLSYFHHC ALRMSCVDLA RAFCFLADKG FCKHSGEQVL NERQTKQVNA IMATSGLYDE 

       250        260        270        280        290        300 
AGNFAYRVGL PGKSGVGGGI IAVVPGRFTV CVWSPELNAA GNSLAGIAAL EKLSERIGWS 


IF 

« Hide

References

[1]"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial."
Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.
Genome Biol. 7:R90.1-R90.14(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UCBPP-PA14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000438 Genomic DNA. Translation: ABJ10818.1.
RefSeqYP_791613.1. NC_008463.1.

3D structure databases

ProteinModelPortalQ02KC3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208963.PA14_43320.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ10818; ABJ10818; PA14_43320.
GeneID4381654.
KEGGpau:PA14_43320.
PATRIC19853218. VBIPseAer79785_3552.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAVNSIMAT.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycPAER208963:GI5K-3503-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_PSEAB
AccessionPrimary (citable) accession number: Q02KC3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families