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Q02G60 (RLMG_PSEAB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174
Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG
Gene names
Name:rlmG
Ordered Locus Names:PA14_61090
OrganismPseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP]
Taxonomic identifier208963 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859

Catalytic activity

S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859

Subcellular location

Cytoplasm Potential HAMAP MF_01859.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

rRNA (guanine-N2-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 374374Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859
PRO_0000366474

Sequences

Sequence LengthMass (Da)Tools
Q02G60 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: C7C6DAF03D709AFF

FASTA37440,506
        10         20         30         40         50         60 
MPLFATPFAQ LDLVRQPEQD GEPLQAFDAA DEYLLNQLHE RGVTAQCRVL VLNDAFGALA 

        70         80         90        100        110        120 
ASLAPHVQVT SSGDSHLGFL ALRKNLARNG LDLGSVRFVP ASETAVGPFD HVLVKVPKTL 

       130        140        150        160        170        180 
ALLEEQLIRL HGQLAPGAQV VAAGMVKHLP RAAGDLLERY IGPMHASLAV KKARLLIAEA 

       190        200        210        220        230        240 
AERPQPRSPY PTRYRLEQPP LTLLNHANVF CREGLDIGTR AFLPHLPRSL GALRAADLGC 

       250        260        270        280        290        300 
GNGVLGIAYA LLNPQAELTL VDESYMAVQS ARENWRAALG ERPATFRADD GLAGQAAGSL 

       310        320        330        340        350        360 
DLVLCNPPFH QQQVVGDFLA WRMFLQARDA LAAGGELWIV GNRHLGYHAK LKRLFRGVEQ 

       370 
VAANPKFVIL KAGK

« Hide

References

[1]"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial."
Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.
Genome Biol. 7:R90.1-R90.14(2006) [PubMed: 17038190] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UCBPP-PA14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000438 Genomic DNA. Translation: ABJ13995.1.
RefSeqYP_793076.1. NC_008463.1.

3D structure databases

ProteinModelPortalQ02G60.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ02G60.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4382983.
GenomeReviewsGene locus PA14_61090 in contig CP000438_GR.
KEGGpau:PA14_61090.
NMPDRfig|208963.3.peg.2228.
PATRIC19856180. VBIPseAer79785_5014.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2813.
HOGENOMHBG321931.
OMANRHLGYH.
ProtClustDBCLSK868782.

Enzyme and pathway databases

BioCycPAER208963:PA14_61090-MONOMER.

Family and domain databases

HAMAPMF_01859. 23SrRNA_methyltr_G.
[Tree]
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR007848. Small_mtfrase.
[Graphical view]
KOK00564.
PfamPF05175. MTS. 1 hit.
[Graphical view]
PIRSFPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRLMG_PSEAB
AccessionPrimary (citable) accession number: Q02G60
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 14, 2006
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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