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Q02DH2 (Q02DH2_PSEAB) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase-binding transcription factor DksA HAMAP-Rule MF_00926
Gene names
Name:dksA HAMAP-Rule MF_00926
Ordered Locus Names:PA14_73020 EMBL ABJ14923.1
OrganismPseudomonas aeruginosa (strain UCBPP-PA14) [Complete proteome] [HAMAP] EMBL ABJ14923.1
Taxonomic identifier208963 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length134 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression By similarity. HAMAP-Rule MF_00926

Subunit structure

Interacts directly with the RNA polymerase By similarity. HAMAP-Rule MF_00926

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00926.

Sequence similarities

Belongs to the DksA family. HAMAP-Rule MF_00926

Contains 1 dksA C4-type zinc finger. HAMAP-Rule MF_00926

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP-Rule MF_00926
   DomainZinc-finger HAMAP-Rule MF_00926
   LigandMetal-binding
Zinc
   Technical term3D-structure PDB 4IJJ
Complete proteome
Gene Ontology (GO)
   Biological_processregulation of gene expression

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Zinc finger96 – 12025dksA C4-type By similarity HAMAP-Rule MF_00926

Sites

Binding site1111Sulfate PDB 4IJJ
Binding site1151Sulfate PDB 4IJJ

Sequences

Sequence LengthMass (Da)Tools
Q02DH2 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 88E8A7F687B692A0

FASTA13416,043
        10         20         30         40         50         60 
MTEQELLAQP DAAYMDEAQQ DFFRDLLLRQ RQELQARIEG EFGELRDLER PSDEADLASR 

        70         80         90        100        110        120 
EEQRQWQLRL LEREKKLLDK IDEALERLAR GDYGWCQETG EPIGLRRLLL RPTATLCIEA 

       130 
KERQEKRERH VRHN 

« Hide

References

« Hide 'large scale' references
[1]"Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial."
Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S., Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.
Genome Biol. 7:R90.1-R90.14(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UCBPP-PA14 EMBL ABJ14923.1.
[2]"DksA2, a zinc-independent structural analog of the transcription factor DksA."
Furman R., Biswas T., Danhart E.M., Foster M.P., Tsodikov O.V., Artsimovitch I.
FEBS Lett. 587:614-619(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.25 ANGSTROMS) IN COMPLEX WITH SULFATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000438 Genomic DNA. Translation: ABJ14923.1.
RefSeqYP_794014.1. NC_008463.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4IJJX-ray3.25A/B/C1-134[»]
ProteinModelPortalQ02DH2.
SMRQ02DH2. Positions 3-130.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208963.PA14_73020.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ14923; ABJ14923; PA14_73020.
GeneID4385264.
KEGGpau:PA14_73020.
PATRIC19858165. VBIPseAer79785_5988.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1734.
HOGENOMHOG000178408.
KOK06204.
OMAGEYGWCR.
OrthoDBEOG6JDWD6.
ProtClustDBCLSK869431.

Enzyme and pathway databases

BioCycPAER208963:GI5K-5944-MONOMER.

Family and domain databases

HAMAPMF_00926. DksA.
InterProIPR012784. DksA_RNA_pol-bd.
IPR000962. Znf_DskA_TraR.
[Graphical view]
PfamPF01258. zf-dskA_traR. 1 hit.
[Graphical view]
TIGRFAMsTIGR02420. dksA. 1 hit.
PROSITEPS51128. ZF_DKSA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ02DH2_PSEAB
AccessionPrimary (citable) accession number: Q02DH2
Entry history
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)