ID   Q02CK9_SOLUE            Unreviewed;       358 AA.
AC   Q02CK9;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE   Flags: Precursor;
GN   OrderedLocusNames=Acid_0193 {ECO:0000313|EMBL:ABJ81207.1};
OS   Solibacter usitatus (strain Ellin6076).
OC   Bacteria; Acidobacteriota; Terriglobia; Bryobacterales; Solibacteraceae;
OC   Solibacter.
OX   NCBI_TaxID=234267 {ECO:0000313|EMBL:ABJ81207.1};
RN   [1] {ECO:0000313|EMBL:ABJ81207.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ellin6076 {ECO:0000313|EMBL:ABJ81207.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Janssen P.H., Kuske C.R., Richardson P.;
RT   "Complete sequence of Solibacter usitatus Ellin6076.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000473; ABJ81207.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q02CK9; -.
DR   STRING; 234267.Acid_0193; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; sus:Acid_0193; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_0; -.
DR   InParanoid; Q02CK9; -.
DR   OrthoDB; 127067at2; -.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:ABJ81207.1};
KW   Hydrolase {ECO:0000313|EMBL:ABJ81207.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..358
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004163620"
FT   DOMAIN          49..327
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   358 AA;  38810 MW;  E80F9F1580E876CB CRC64;
     MFSRAGAVTL LACAGLMAGA EPFQTDIFRA GEGGYHSYRI PALIVSAKGT LLAFCEGRRN
     SASDTGDIDV LLRRSFDGGK TWAALQKVAD MGEDTVGNPT PVIERKSGAI LLLLTSNPGQ
     VTERQTGPRD RTVWITRSMD DGATWSAPAE ITSQVKHADW TWYATGPGNG IQLRGGRLVI
     PCDHNTADGA RYSHVIYSDD GGTTWKIGGI AEDKTNESAI VELKSGELLF NMRSYHGKNR
     RAVQRSTDGG LMWGPLNLDE TLIEPVCQAS MITDSKGRVW FSNPAATTRS RMTVRMSNDG
     GRTWAASQVI HQGPAAYSSL AMLRGGGIGL LYELGESKPY ERIAFARFEV SWVKGKMK
//