Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q02C42 (ALLB_SOLUE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Ordered Locus Names:Acid_0362
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter

Protein attributes

Sequence length457 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Ontologies

Keywords
   Biological processPurine metabolism
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processallantoin catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

purine nucleobase metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionallantoinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

cobalt ion binding

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 457457Allantoinase HAMAP-Rule MF_01645
PRO_0000317686

Sites

Metal binding581Zinc 1 By similarity
Metal binding601Zinc 1 By similarity
Metal binding1451Zinc 1; via carbamate group By similarity
Metal binding1451Zinc 2; via carbamate group By similarity
Metal binding1811Zinc 2 By similarity
Metal binding2371Zinc 2 By similarity
Metal binding3101Zinc 1 By similarity

Amino acid modifications

Modified residue1451N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q02C42 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 1ECA27B484510AA9

FASTA45748,807
        10         20         30         40         50         60 
MSECVVRGGQ VVQAGGVVSA DVAIEDGRIS AIGPELPGAK REINARGLTV FPGVIDDHLH 

        70         80         90        100        110        120 
FNEPGRTEWE GAATGSRALA AGGGTAFFDM PLNSTPCTVD RAAFAGKRAA LERASIADFA 

       130        140        150        160        170        180 
LWGGIVPGNL SELAPLAESG VIGFKAFLSD SGLPEFPRAD DLTLYEGMRE AARLGLPVAV 

       190        200        210        220        230        240 
HAESEEITSR LTRRARDAGR TSARDYLDSR PVIAEVEAIH RAALLAREAG CKLHIVHISS 

       250        260        270        280        290        300 
GRGVAAALEA RTMGTDIAIE TCAHYLFFTE DDLLRLGAIA KCAPPLRDRQ EFDRLWAHVL 

       310        320        330        340        350        360 
GGIVDVVASD HSPAPPAMKT GDDFFAIWGG IAGVQSTLAV LLEAGHFQRG LRLERIAELT 

       370        380        390        400        410        420 
AGYPARRFAL HNKGSIAVGN DADLTLVDMD GQENLEPESL WQKHPVNPYT GNSFRGSIRR 

       430        440        450 
TMLRGTTIFN HDEITVKSGG QLLRPKANTY ATSGIHP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000473 Genomic DNA. Translation: ABJ81374.1.
RefSeqYP_821659.1. NC_008536.1.

3D structure databases

ProteinModelPortalQ02C42.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING234267.Acid_0362.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ81374; ABJ81374; Acid_0362.
GeneID4431577.
KEGGsus:Acid_0362.
PATRIC32002764. VBICanSol30224_0382.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0044.
HOGENOMHOG000219146.
KOK01466.
OMACSPWEGH.
OrthoDBEOG6KHFW6.

Enzyme and pathway databases

BioCycSUSI234267:GHSK-366-MONOMER.
UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 1 hit.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_SOLUE
AccessionPrimary (citable) accession number: Q02C42
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways