Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Solibacter usitatus (strain Ellin6076)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei102Transition state stabilizerUniRule annotation1
Active sitei106Proton acceptorUniRule annotation1
Metal bindingi268Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciCSOL234267:G1G7G-1138-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:Acid_1112
OrganismiSolibacter usitatus (strain Ellin6076)
Taxonomic identifieri234267 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter
Proteomesi
  • UP000000671 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003549361 – 743Catalase-peroxidaseAdd BLAST743

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki105 ↔ 227Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-253)UniRule annotation
Cross-linki227 ↔ 253Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-105)UniRule annotation

Post-translational modificationi

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Proteomic databases

PRIDEiQ02A20

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi234267.Acid_1112

Structurei

3D structure databases

ProteinModelPortaliQ02A20
SMRiQ02A20
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X Bacteria
COG0376 LUCA
HOGENOMiHOG000218110
KOiK03782
OMAiPEEDIYW
OrthoDBiPOG091H05R1

Family and domain databases

HAMAPiMF_01961 Catal_peroxid, 1 hit
InterProiView protein in InterPro
IPR000763 Catalase_peroxidase
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
PANTHERiPTHR30555 PTHR30555, 1 hit
PfamiView protein in Pfam
PF00141 peroxidase, 2 hits
PRINTSiPR00460 BPEROXIDASE
PR00458 PEROXIDASE
SUPFAMiSSF48113 SSF48113, 2 hits
TIGRFAMsiTIGR00198 cat_per_HPI, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 2 hits

Sequencei

Sequence statusi: Complete.

Q02A20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKQSNDAAV AGAPNDHGAA KCPVAHTAHG RRNRDWWPDA LDISTLHRNS
60 70 80 90 100
SLSDPMGSGF DYAMEFESLD LQAVIKDLHA LMTDSQDWWP ADFGHYGGLM
110 120 130 140 150
IRMAWHSAGT YRITDGRGGA GAGQQRFAPL NSWPDNANLD KARRLLWPVK
160 170 180 190 200
QKYGDKISWA DLMVLAGNVA LESMGFKTFG FAGGRSDVWE PEELYWGPEG
210 220 230 240 250
TWLGDERYSG ERQLSEPLGA VQMGLIYVNP EGPNGNPDPV AAAKDIRETF
260 270 280 290 300
FRMAMNDEET VALIAGGHTF GKTHGAGDPS LVGPDPESGA LEDQGLGWKS
310 320 330 340 350
KFGTGFGADA ITGGPEVTWS QTPTQWSNSF FKNLFENEWE LTNSPAGAKQ
360 370 380 390 400
WRAKNGQATI PDPFDKSKKR VPTMLTTDLS LRFDPAYEKI SRRFYENPDQ
410 420 430 440 450
FADAFARAWF KLTHRDMGPI ARYLGPLVPK ETLLWQDPIP PVDHPLIDEN
460 470 480 490 500
DASALKAKIL ASGLSTSDLV STAWASASTF RGSDKRGGAN GARIRLAPQK
510 520 530 540 550
DWEVNQPKQL AKVLEKLETI GKEFGKKVSL ADLIVLGGDA AIEKAAKDAG
560 570 580 590 600
VEVKIPFTPG RMDASQEQTD VASFAPLEPK ADGFRNYIGR KTQFLQPEEA
610 620 630 640 650
LVDRAQLLRL TGPEMTVLVG GLRVLGANTA GSKHGVFTAT PGVLTNDFFV
660 670 680 690 700
NLLDMRTHWQ PAGGEEGVYE GRDRKTNALK WTGTRVDLIF GSHSQLRAFA
710 720 730 740
EVYAWAGSKE KFVKDFAAAW NKVMNLDRYD VARTGETKKA AVV
Length:743
Mass (Da):81,479
Last modified:November 14, 2006 - v1
Checksum:i15497A51D56B3C8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000473 Genomic DNA Translation: ABJ82106.1
RefSeqiWP_011682882.1, NC_008536.1

Genome annotation databases

EnsemblBacteriaiABJ82106; ABJ82106; Acid_1112
KEGGisus:Acid_1112

Similar proteinsi

Entry informationi

Entry nameiKATG_SOLUE
AccessioniPrimary (citable) accession number: Q02A20
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 14, 2006
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health