ID   Q029S4_SOLUE            Unreviewed;       848 AA.
AC   Q029S4;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=Acid_1208 {ECO:0000313|EMBL:ABJ82202.1};
OS   Solibacter usitatus (strain Ellin6076).
OC   Bacteria; Acidobacteriota; Terriglobia; Bryobacterales; Solibacteraceae;
OC   Solibacter.
OX   NCBI_TaxID=234267 {ECO:0000313|EMBL:ABJ82202.1};
RN   [1] {ECO:0000313|EMBL:ABJ82202.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ellin6076 {ECO:0000313|EMBL:ABJ82202.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Janssen P.H., Kuske C.R., Richardson P.;
RT   "Complete sequence of Solibacter usitatus Ellin6076.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; CP000473; ABJ82202.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q029S4; -.
DR   STRING; 234267.Acid_1208; -.
DR   KEGG; sus:Acid_1208; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_007799_0_0_0; -.
DR   InParanoid; Q029S4; -.
DR   OrthoDB; 9801841at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00220; S_TKc; 1.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABJ82202.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABJ82202.1};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transferase {ECO:0000313|EMBL:ABJ82202.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        401..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          83..382
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REPEAT          604..637
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   848 AA;  95482 MW;  9811D8901E04C9AE CRC64;
     MTREEWQRVK DILHNALDLP RSGRAAFLDA ACNGDPTLRG EVESLLASHE EAGTFIEEPV
     ASAPKLTPPM PENLGIGSDL GPYRIVQLIA EGGMGAVYQA VRVDDLYRKV VAVKVIRRGV
     FGEFALRRFD IERQILAHLD HPNIAKLLDG GATPDGRPFF VMDFIAGTPI DEYCDHHKLG
     IRERLDFFLK VCSAVHYAHQ NLVIHRDLKP GNILVTEEGA LKLLDFGIAK LLDPDALAGE
     DEPTLTTVHA MTPEYASPEQ LHGLQVTTAS DVYSLGVLLY RLMTGHRPYA GDSRSIEELW
     EHIRSRPPRR PSTVIAANDD GVTPETVCSA RSTKPERLQR QLSGDLDNIL MMALRKEPER
     RYCSVEQFAN DLRRHLQGHP VTARPDTIRY RAGKFIQRHR GGVFAAAMVI VTLIAGIITT
     SWQWHVANRE RQKAEQRFQD VRGLANSVLF ELHDAIVPLP GSTPARELLI KRAQRYLDSL
     ATEPGVDDSL QHERAMAYER IGDVLGLPVQ PNLGQSAEAL ASYHRALEIE RQLADHDYAN
     ITVLRRDMAR IYNHICRVEQ ETGKFKESLE NCRESSRIQE EQLRLHPDDV VLRADLATTY
     GNMAGAYLAL GDYAHTEEQR SQVLREFQEL HRLEPDNESF LYGLANAYHR MANLQEQTKH
     YAAARANVLQ AIELFDQISA RHPKDILKRS DWTFAQQRLG SILISTGDLK GALAAFEQVL
     PIREQLQHLD PKDARARLNL ANSHASVGFV LLELGQAREA RGHFEQQRRL DEELIRLDPM
     GVAYQYSLSE ALENLGRVAQ RLGERERGKT YLREALKIYD ELSARGAISA EYASVPARIR
     REMGGKTN
//