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Protein
Submitted name:

(P)ppGpp synthetase I, SpoT/RelA

Gene

Acid_1285

Organism
Solibacter usitatus (strain Ellin6076)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.UniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. GTP diphosphokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. guanosine tetraphosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

BioCyciSUSI234267:GHSK-1297-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
(P)ppGpp synthetase I, SpoT/RelAImported (EC:2.7.6.5Imported)
Gene namesi
Ordered Locus Names:Acid_1285Imported
OrganismiSolibacter usitatus (strain Ellin6076)Imported
Taxonomic identifieri234267 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter
ProteomesiUP000000671: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi234267.Acid_1285.

Structurei

3D structure databases

ProteinModelPortaliQ029J7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the relA/spoT family.UniRule annotation
Contains HD domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0317.
HOGENOMiHOG000018299.
KOiK00951.
OMAiLDWLNFV.
OrthoDBiEOG6SV551.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR002912. ACT_dom.
IPR012675. Beta-grasp_dom.
IPR003607. HD/PDEase_dom.
IPR004811. RelA/Spo_fam.
IPR007685. RelA_SpoT.
IPR004095. TGS.
IPR012676. TGS-like.
[Graphical view]
PfamiPF04607. RelA_SpoT. 1 hit.
PF02824. TGS. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00954. RelA_SpoT. 1 hit.
[Graphical view]
SUPFAMiSSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00691. spoT_relA. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q029J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSESTSLSD AAPVLPPTDP VEQLYRELEA KIREYRPKDD LTALEKAFRF
60 70 80 90 100
ASKYHEGQTR DSGEPYMAHP VMVAHILADM RMDVVAMETG LLHDVVEDTS
110 120 130 140 150
VTVEQVRKEF GPDVARCVDG VTKLTKLDVF SAEDRQAESV RKMLLAMVED
160 170 180 190 200
IRVILVKLAD RIHNMRTLGY LNPERRERIA RETIEIYAPI AHRLGMGKVR
210 220 230 240 250
GELEDLAFQH LEPDAYQEIL SAIESKRHSN EEFLNEIRHT VESELRREGI
260 270 280 290 300
PARIDGRVKR PYSVFQKMRR QKISLDQVYD LMALRILTDS VKNCYAALGV
310 320 330 340 350
IHNKWRPIPG RIKDFIAIPR PNLYQSLHTS VVGPHGQTFE VQIRTEEMHR
360 370 380 390 400
IAEEGIAAHW KYKEGRKGPA VDDQRIAWLR HLVEWQRDVQ DPGEFMSTLK
410 420 430 440 450
VDLYPEEAYT FTPRGKVIVL PRDATPIDFA YAIHSDVGST CVGAKVNGRI
460 470 480 490 500
VPLRSTLRNG DIVEIMTQPG HEPSKDWLAF VKTSRARNKI KHLINASERI
510 520 530 540 550
KAVEIGQKYL EKEARRLGVS LGKVTKSEME KVASEYGYSK MEDLYAALGY
560 570 580 590 600
GKFSARQVLV KIAPGVVKEE TVEAKPAAEA APQPAPGARK GEGDGVIKVR
610 620 630 640 650
GIDDLMVYRA KCCNPIRGEA IVGYVTRGKG VAVHSRACPN VQSLMYDVER
660 670 680 690 700
KIEVEWARAA EDSFPVRIVV HTDDRPGMLN QLTGVLSDEN TNIRSLEAKT
710 720 730 740
ETDHDGGVVE MTVDVRDKKQ LEKLVAAMRR ISGVRDVERL FT
Length:742
Mass (Da):83,774
Last modified:November 14, 2006 - v1
Checksum:i66F3939A9AC8C489
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000473 Genomic DNA. Translation: ABJ82279.1.
RefSeqiYP_822564.1. NC_008536.1.

Genome annotation databases

EnsemblBacteriaiABJ82279; ABJ82279; Acid_1285.
GeneIDi4430552.
KEGGisus:Acid_1285.
PATRICi32004719. VBICanSol30224_1348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000473 Genomic DNA. Translation: ABJ82279.1.
RefSeqiYP_822564.1. NC_008536.1.

3D structure databases

ProteinModelPortaliQ029J7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi234267.Acid_1285.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ82279; ABJ82279; Acid_1285.
GeneIDi4430552.
KEGGisus:Acid_1285.
PATRICi32004719. VBICanSol30224_1348.

Phylogenomic databases

eggNOGiCOG0317.
HOGENOMiHOG000018299.
KOiK00951.
OMAiLDWLNFV.
OrthoDBiEOG6SV551.

Enzyme and pathway databases

BioCyciSUSI234267:GHSK-1297-MONOMER.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR002912. ACT_dom.
IPR012675. Beta-grasp_dom.
IPR003607. HD/PDEase_dom.
IPR004811. RelA/Spo_fam.
IPR007685. RelA_SpoT.
IPR004095. TGS.
IPR012676. TGS-like.
[Graphical view]
PfamiPF04607. RelA_SpoT. 1 hit.
PF02824. TGS. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00954. RelA_SpoT. 1 hit.
[Graphical view]
SUPFAMiSSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00691. spoT_relA. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ellin6076Imported.

Entry informationi

Entry nameiQ029J7_SOLUE
AccessioniPrimary (citable) accession number: Q029J7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: January 7, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.