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Q02930

- CREB5_HUMAN

UniProt

Q02930 - CREB5_HUMAN

Protein

Cyclic AMP-responsive element-binding protein 5

Gene

CREB5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 128 (01 Oct 2014)
      Sequence version 3 (31 May 2011)
      Previous versions | rss
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    Functioni

    Binds to the cAMP response element and activates transcription.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri16 – 4025C2H2-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein binding Source: UniProtKB
    3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
    4. sequence-specific DNA binding Source: InterPro
    5. sequence-specific DNA binding transcription factor activity Source: UniProtKB

    GO - Biological processi

    1. adipose tissue development Source: Ensembl
    2. fat cell differentiation Source: Ensembl
    3. positive regulation of transcription, DNA-templated Source: UniProtKB
    4. transcription from RNA polymerase II promoter Source: ProtInc

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclic AMP-responsive element-binding protein 5
    Short name:
    CREB-5
    Short name:
    cAMP-responsive element-binding protein 5
    Alternative name(s):
    CRE-BPa
    Gene namesi
    Name:CREB5
    Synonyms:CREBPA
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:16844. CREB5.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. extracellular vesicular exosome Source: UniProt
    2. nucleus Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134930491.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 508508Cyclic AMP-responsive element-binding protein 5PRO_0000076604Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei59 – 591Phosphothreonine1 Publication
    Modified residuei61 – 611Phosphothreonine1 Publication
    Modified residuei137 – 1371Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ02930.
    PaxDbiQ02930.
    PRIDEiQ02930.

    PTM databases

    PhosphoSiteiQ02930.

    Expressioni

    Gene expression databases

    ArrayExpressiQ02930.
    BgeeiQ02930.
    CleanExiHS_CREB5.
    GenevestigatoriQ02930.

    Organism-specific databases

    HPAiHPA050020.

    Interactioni

    Subunit structurei

    Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.1 Publication

    Protein-protein interaction databases

    BioGridi114954. 5 interactions.
    IntActiQ02930. 2 interactions.
    MINTiMINT-267970.
    STRINGi9606.ENSP00000350359.

    Structurei

    3D structure databases

    ProteinModelPortaliQ02930.
    SMRiQ02930. Positions 10-46, 377-436.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini375 – 43864bZIPPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni377 – 39721Basic motifPROSITE-ProRule annotationAdd
    BLAST
    Regioni403 – 43129Leucine-zipperPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the bZIP family.Curated
    Contains 1 bZIP (basic-leucine zipper) domain.PROSITE-ProRule annotation
    Contains 1 C2H2-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri16 – 4025C2H2-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG286140.
    HOGENOMiHOG000220894.
    HOVERGENiHBG004300.
    InParanoidiQ02930.
    KOiK09047.
    OMAiISMHNTV.
    OrthoDBiEOG741Z31.
    PhylomeDBiQ02930.

    Family and domain databases

    Gene3Di3.30.160.60. 1 hit.
    InterProiIPR004827. bZIP.
    IPR016378. TF_cAMP-dep.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00170. bZIP_1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003153. ATF2_CRE-BP1. 1 hit.
    SMARTiSM00338. BRLZ. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view]
    PROSITEiPS50217. BZIP. 1 hit.
    PS00036. BZIP_BASIC. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 1 hit.
    PS50157. ZINC_FINGER_C2H2_2. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q02930-1) [UniParc]FASTAAdd to Basket

    Also known as: Alpha

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MIYEESKMNL EQERPFVCSA PGCSQRFPTE DHLMIHRHKH EMTLKFPSIK    50
    TDNMLSDQTP TPTRFLKNCE EVGLFSELDC SLEHEFRKAQ EEESSKRNIS 100
    MHNAVGGAMT GPGTHQLSSA RLPNHDTNVV IQQAMPSPQS SSVITQAPST 150
    NRQIGPVPGS LSSLLHLHNR QRQPMPASMP GTLPNPTMPG SSAVLMPMER 200
    QMSVNSSIMG MQGPNLSNPC ASPQVQPMHS EAKMRLKAAL THHPAAMSNG 250
    NMNTMGHMME MMGSRQDQTP HHHMHSHPHQ HQTLPPHHPY PHQHQHPAHH 300
    PHPQPHHQQN HPHHHSHSHL HAHPAHHQTS PHPPLHTGNQ AQVSPATQQM 350
    QPTQTIQPPQ PTGGRRRRVV DEDPDERRRK FLERNRAAAT RCRQKRKVWV 400
    MSLEKKAEEL TQTNMQLQNE VSMLKNEVAQ LKQLLLTHKD CPITAMQKES 450
    QGYLSPESSP PASPVPACSQ QQVIQHNTIT TSSSVSEVVG SSTLSQLTTH 500
    RTDLNPIL 508
    Length:508
    Mass (Da):56,918
    Last modified:May 31, 2011 - v3
    Checksum:iDF96F33AE562F1AD
    GO
    Isoform 2 (identifier: Q02930-2) [UniParc]FASTAAdd to Basket

    Also known as: Beta

    The sequence of this isoform differs from the canonical sequence as follows:
         1-7: Missing.

    Show »
    Length:501
    Mass (Da):56,037
    Checksum:i9D67856759DB9957
    GO
    Isoform 3 (identifier: Q02930-3) [UniParc]FASTAAdd to Basket

    Also known as: Gamma

    The sequence of this isoform differs from the canonical sequence as follows:
         1-33: Missing.

    Show »
    Length:475
    Mass (Da):53,063
    Checksum:iBD75DF80FE7145E9
    GO
    Isoform 4 (identifier: Q02930-4) [UniParc]FASTAAdd to Basket

    Also known as: Delta

    The sequence of this isoform differs from the canonical sequence as follows:
         1-16: MIYEESKMNLEQERPF → MFCTSGGNSASVMSMR
         17-155: Missing.

    Show »
    Length:369
    Mass (Da):41,161
    Checksum:i7DC1C71C6A74DEB5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti16 – 161F → S in AAA52072. (PubMed:8440710)Curated
    Sequence conflicti16 – 161F → S in AAC37525. (PubMed:8378084)Curated
    Sequence conflicti211 – 2122MQ → IE in AAA52072. (PubMed:8440710)Curated
    Sequence conflicti211 – 2122MQ → IE in AAC37525. (PubMed:8378084)Curated
    Sequence conflicti211 – 2122MQ → IE in AAC37526. (PubMed:8378084)Curated
    Sequence conflicti211 – 2122MQ → IE in AAC37527. (PubMed:8378084)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 3333Missing in isoform 3. 2 PublicationsVSP_050011Add
    BLAST
    Alternative sequencei1 – 1616MIYEE…QERPF → MFCTSGGNSASVMSMR in isoform 4. 3 PublicationsVSP_050012Add
    BLAST
    Alternative sequencei1 – 77Missing in isoform 2. 1 PublicationVSP_050010
    Alternative sequencei17 – 155139Missing in isoform 4. 3 PublicationsVSP_050013Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L05515 mRNA. Translation: AAA52072.1.
    L05911 mRNA. Translation: AAC37525.1.
    L05912 mRNA. Translation: AAC37527.1.
    L05913 mRNA. Translation: AAC37526.1.
    AK292916 mRNA. Translation: BAF85605.1.
    AK300455 mRNA. Translation: BAG62175.1.
    AK316187 mRNA. Translation: BAH14558.1.
    AB451409 mRNA. Translation: BAG70223.1.
    AC003074 Genomic DNA. Translation: AAS00387.1.
    AC005105 Genomic DNA. Translation: AAP22329.1.
    AC005013 Genomic DNA. No translation available.
    AC006331 Genomic DNA. No translation available.
    AC006367 Genomic DNA. No translation available.
    AC006980 Genomic DNA. No translation available.
    CH471073 Genomic DNA. Translation: EAW93908.1.
    CH471073 Genomic DNA. Translation: EAW93910.1.
    BC059400 mRNA. Translation: AAH59400.2.
    CCDSiCCDS43562.1. [Q02930-3]
    CCDS43563.1. [Q02930-4]
    CCDS5417.1. [Q02930-1]
    CCDS5418.1. [Q02930-2]
    PIRiA45477.
    I78877.
    RefSeqiNP_001011666.1. NM_001011666.1. [Q02930-4]
    NP_004895.2. NM_004904.2. [Q02930-2]
    NP_878901.2. NM_182898.2. [Q02930-1]
    NP_878902.2. NM_182899.3. [Q02930-3]
    XP_005249963.1. XM_005249906.1. [Q02930-2]
    UniGeneiHs.437075.

    Genome annotation databases

    EnsembliENST00000357727; ENSP00000350359; ENSG00000146592. [Q02930-1]
    ENST00000396298; ENSP00000379592; ENSG00000146592. [Q02930-4]
    ENST00000396299; ENSP00000379593; ENSG00000146592. [Q02930-3]
    ENST00000396300; ENSP00000379594; ENSG00000146592. [Q02930-2]
    ENST00000409603; ENSP00000387197; ENSG00000146592. [Q02930-3]
    GeneIDi9586.
    KEGGihsa:9586.
    UCSCiuc003szo.3. human. [Q02930-1]
    uc003szs.3. human. [Q02930-4]

    Polymorphism databases

    DMDMi334302918.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L05515 mRNA. Translation: AAA52072.1 .
    L05911 mRNA. Translation: AAC37525.1 .
    L05912 mRNA. Translation: AAC37527.1 .
    L05913 mRNA. Translation: AAC37526.1 .
    AK292916 mRNA. Translation: BAF85605.1 .
    AK300455 mRNA. Translation: BAG62175.1 .
    AK316187 mRNA. Translation: BAH14558.1 .
    AB451409 mRNA. Translation: BAG70223.1 .
    AC003074 Genomic DNA. Translation: AAS00387.1 .
    AC005105 Genomic DNA. Translation: AAP22329.1 .
    AC005013 Genomic DNA. No translation available.
    AC006331 Genomic DNA. No translation available.
    AC006367 Genomic DNA. No translation available.
    AC006980 Genomic DNA. No translation available.
    CH471073 Genomic DNA. Translation: EAW93908.1 .
    CH471073 Genomic DNA. Translation: EAW93910.1 .
    BC059400 mRNA. Translation: AAH59400.2 .
    CCDSi CCDS43562.1. [Q02930-3 ]
    CCDS43563.1. [Q02930-4 ]
    CCDS5417.1. [Q02930-1 ]
    CCDS5418.1. [Q02930-2 ]
    PIRi A45477.
    I78877.
    RefSeqi NP_001011666.1. NM_001011666.1. [Q02930-4 ]
    NP_004895.2. NM_004904.2. [Q02930-2 ]
    NP_878901.2. NM_182898.2. [Q02930-1 ]
    NP_878902.2. NM_182899.3. [Q02930-3 ]
    XP_005249963.1. XM_005249906.1. [Q02930-2 ]
    UniGenei Hs.437075.

    3D structure databases

    ProteinModelPortali Q02930.
    SMRi Q02930. Positions 10-46, 377-436.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 114954. 5 interactions.
    IntActi Q02930. 2 interactions.
    MINTi MINT-267970.
    STRINGi 9606.ENSP00000350359.

    PTM databases

    PhosphoSitei Q02930.

    Polymorphism databases

    DMDMi 334302918.

    Proteomic databases

    MaxQBi Q02930.
    PaxDbi Q02930.
    PRIDEi Q02930.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000357727 ; ENSP00000350359 ; ENSG00000146592 . [Q02930-1 ]
    ENST00000396298 ; ENSP00000379592 ; ENSG00000146592 . [Q02930-4 ]
    ENST00000396299 ; ENSP00000379593 ; ENSG00000146592 . [Q02930-3 ]
    ENST00000396300 ; ENSP00000379594 ; ENSG00000146592 . [Q02930-2 ]
    ENST00000409603 ; ENSP00000387197 ; ENSG00000146592 . [Q02930-3 ]
    GeneIDi 9586.
    KEGGi hsa:9586.
    UCSCi uc003szo.3. human. [Q02930-1 ]
    uc003szs.3. human. [Q02930-4 ]

    Organism-specific databases

    CTDi 9586.
    GeneCardsi GC07P028305.
    HGNCi HGNC:16844. CREB5.
    HPAi HPA050020.
    neXtProti NX_Q02930.
    PharmGKBi PA134930491.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG286140.
    HOGENOMi HOG000220894.
    HOVERGENi HBG004300.
    InParanoidi Q02930.
    KOi K09047.
    OMAi ISMHNTV.
    OrthoDBi EOG741Z31.
    PhylomeDBi Q02930.

    Miscellaneous databases

    ChiTaRSi CREB5. human.
    GeneWikii CREB5.
    GenomeRNAii 9586.
    NextBioi 35963.
    PROi Q02930.

    Gene expression databases

    ArrayExpressi Q02930.
    Bgeei Q02930.
    CleanExi HS_CREB5.
    Genevestigatori Q02930.

    Family and domain databases

    Gene3Di 3.30.160.60. 1 hit.
    InterProi IPR004827. bZIP.
    IPR016378. TF_cAMP-dep.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00170. bZIP_1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003153. ATF2_CRE-BP1. 1 hit.
    SMARTi SM00338. BRLZ. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view ]
    PROSITEi PS50217. BZIP. 1 hit.
    PS00036. BZIP_BASIC. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 1 hit.
    PS50157. ZINC_FINGER_C2H2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1."
      Nomura N., Zu Y.-L., Maekawa T., Tabata S., Akiyama T., Ishii S.
      J. Biol. Chem. 268:4259-4266(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBUNIT.
    2. "Regulation of trans-activating capacity of CRE-BPa by phorbol ester tumor promoter TPA."
      Zu Y.-L., Maekawa T., Nomura N., Nakata T., Ishii S.
      Oncogene 8:2749-2758(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4), FUNCTION.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4).
      Tissue: Embryo, Placenta and Trachea.
    4. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N., Kawamura Y., Fukumoto A., Miura A., Honma R., Satoh R., Wakamatsu A., Yamamoto J., Kimura K., Nishikawa T., Andoh T., Iida Y., Ishikawa K., Ito E., Kagawa N., Kaminaga C., Kanehori K., Kawakami B.
      , Kenmochi K., Kimura R., Kobayashi M., Kuroita T., Kuwayama H., Maruyama Y., Matsuo K., Minami K., Mitsubori M., Mori M., Morishita R., Murase A., Nishikawa A., Nishikawa S., Okamoto T., Sakagami N., Sakamoto Y., Sasaki Y., Seki T., Sono S., Sugiyama A., Sumiya T., Takayama T., Takayama Y., Takeda H., Togashi T., Yahata K., Yamada H., Yanagisawa Y., Endo Y., Imamoto F., Kisu Y., Tanaka S., Isogai T., Imai J., Watanabe S., Nomura N.
      Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    5. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Placenta.
    8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-59; THR-61 AND SER-137, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.

    Entry informationi

    Entry nameiCREB5_HUMAN
    AccessioniPrimary (citable) accession number: Q02930
    Secondary accession number(s): A8KA51
    , B4DU13, B5BUH3, C9JK47, Q05886, Q06246, Q75N02, Q86UJ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 13, 2004
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 128 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3