Q02895 (YP088_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative aryl-alcohol dehydrogenase YPL088W
EC=1.1.1.-

Gene names

Ordered Locus Names:

YPL088W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Putative aryl-alcohol dehydrogenase By similarity.
Induction	By cell wall stress and the YRR1 transcription factor. Ref.3 Ref.4
Sequence similarities	Belongs to the aldo/keto reductase 2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
itself		1	EBI-35030,EBI-35030
MGM1	P32266	1	EBI-35030,EBI-10865
SRP1	Q02821	1	EBI-35030,EBI-1797
UBP6	P43593	1	EBI-35030,EBI-19852
YHR078W	P38799	1	EBI-35030,EBI-24593
YHR080C	P38800	1	EBI-35030,EBI-24597

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Putative aryl-alcohol dehydrogenase YPL088W		PRO_0000238634

Sequences

	Sequence		Length	Mass (Da)
	Q02895 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: E99B1EB62FC880B1	FASTA	342	39,683
	10 20 30 40 50 60 MVLVKQVRLG NSGLKISPIV IGCMSYGSKK WADWVIEDKT QIFKIMKHCY DKGLRTFDTA 70 80 90 100 110 120 DFYSNGLSER IIKEFLEYYS IKRETVVIMT KIYFPVDETL DLHHNFTLNE FEELDLSNQR 130 140 150 160 170 180 GLSRKHIIAG VENSVKRLGT YIDLLQIHRL DHETPMKEIM KALNDVVEAG HVRYIGASSM 190 200 210 220 230 240 LATEFAELQF TADKYGWFQF ISSQSYYNLL YREDERELIP FAKRHNIGLL PWSPNARGML 250 260 270 280 290 300 TRPLNQSTDR IKSDPTFKSL HLDNLEEEQK EIINRVEKVS KDKKVSMAML SIAWVLHKGC 310 320 330 340 HPIVGLNTTA RVDEAIAALQ VTLTEEEIKY LEEPYKPQRQ RC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system." Le Crom S., Devaux F., Marc P., Zhang X., Moye-Rowley W.S., Jacq C. Mol. Cell. Biol. 22:2642-2649(2002) [PubMed: 11909958] [Abstract] Cited for: INDUCTION.
[4]	"Characterization of the transcriptional response to cell wall stress in Saccharomyces cerevisiae." Boorsma A., de Nobel H., ter Riet B., Bargmann B., Brul S., Hellingwerf K.J., Klis F.M. Yeast 21:413-427(2004) [PubMed: 15116342] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U43281 Genomic DNA. Translation: AAB68211.1. BK006949 Genomic DNA. Translation: DAA11345.1.
PIR	S61978.
RefSeq	NP_015237.1. NM_001183902.1.
3D structure databases
ProteinModelPortal	Q02895.
SMR	Q02895. Positions 5-337.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4021N.
IntAct	Q02895. 17 interactions.
MINT	MINT-399381.
STRING	Q02895.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPL088W; YPL088W; YPL088W.
GeneID	856017.
KEGG	sce:YPL088W.
NMPDR	fig|4932.3.peg.6370.
Organism-specific databases
CYGD	YPL088w.
SGD	S000006009. YPL088W.
Phylogenomic databases
eggNOG	fuNOG06224.
GeneTree	EFGT00050000001340.
HOGENOM	HBG605727.
OMA	WVLHKGC.
OrthoDB	EOG4617CT.
Gene expression databases
ArrayExpress	Q02895.
Genevestigator	Q02895.
GermOnline	YPL088W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. IPR023210. NADP_OxRdtase_dom. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
SUPFAM	SSF51430. Aldo/ket_red. 1 hit.
ProtoNet	Search...
Other
NextBio	980917.

Entry information

Entry name

YP088_YEAST

Accession

Primary (citable) accession number: Q02895
Secondary accession number(s): D6W3S9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program