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Protein

Protein MGR2

Gene

MGR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Required for cell viability in cells lacking mitochondrial DNA.1 Publication

GO - Biological processi

  • protein import into mitochondrial inner membrane Source: SGD
  • protein import into mitochondrial matrix Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34001-MONOMER.

Protein family/group databases

TCDBi9.B.181.1.3. the reactive oxygen species modulator 1 (romo1) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MGR2
Alternative name(s):
Mitochondrial genome-required protein 2
Gene namesi
Name:MGR2
Ordered Locus Names:YPL098C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL098C.
SGDiS000006019. MGR2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22CytoplasmicSequence analysisAdd BLAST22
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Topological domaini44 – 56ExtracellularSequence analysisAdd BLAST13
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Topological domaini78 – 113CytoplasmicSequence analysisAdd BLAST36

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002522781 – 113Protein MGR2Add BLAST113

Proteomic databases

MaxQBiQ02889.
PRIDEiQ02889.

Interactioni

Protein-protein interaction databases

BioGridi36082. 228 interactors.
DIPiDIP-4556N.
IntActiQ02889. 1 interactor.
MINTiMINT-521420.
STRINGi4932.YPL098C.

Structurei

3D structure databases

ProteinModelPortaliQ02889.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MGR2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000005315.
HOGENOMiHOG000184556.
InParanoidiQ02889.
OMAiLKMGAMM.
OrthoDBiEOG092C5QP7.

Family and domain databases

InterProiView protein in InterPro
IPR018450. Romo1/Mgr2.
PANTHERiPTHR28525. PTHR28525. 1 hit.
PfamiView protein in Pfam
PF10247. Romo1. 1 hit.
SMARTiView protein in SMART
SM01378. Romo1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q02889-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPLPQNYAQ QQPSNWDKFK MGLMMGTTVG VCTGILFGGF AIATQGPGPD
60 70 80 90 100
GVVRTLGKYI AGSAGTFGLF MSIGSIIRSD SESSPMSHPN LNLQQQARLE
110
MWKLRAKYGI RKD
Length:113
Mass (Da):12,252
Last modified:November 1, 1996 - v1
Checksum:i43BA58C679D86E93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43281 Genomic DNA. Translation: AAB68201.1.
AY558335 Genomic DNA. Translation: AAS56661.1.
BK006949 Genomic DNA. Translation: DAA11334.1.
PIRiS61968.
RefSeqiNP_015227.1. NM_001183912.1.

Genome annotation databases

EnsemblFungiiYPL098C; YPL098C; YPL098C.
GeneIDi856006.
KEGGisce:YPL098C.

Similar proteinsi

Entry informationi

Entry nameiMGR2_YEAST
AccessioniPrimary (citable) accession number: Q02889
Secondary accession number(s): D6W3R8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names