Q02820 (NCE1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-classical export protein 1

Gene names

Name:	NCE101
Synonyms:	NCE1
Ordered Locus Names:	YJL205C
ORF Names:	YJL205BC, YJL205C-A

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	53 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. May be part of the export machinery or may also be a substrate for non-classical export. Ref.1
Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the NCE101 family.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein secretion Inferred from genetic interaction Ref.1. Source: SGD
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 53	53	Non-classical export protein 1		PRO_0000096759
Regions
	Transmembrane	7 – 29	23	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q02820 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 05358FA15499E8B2	FASTA	53	6,337
	10 20 30 40 50 MVQYAPFLLG KFSDPLLAIM VGCLSYYVYE RKMGRPQGHH LHELIKKRWD DRK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A new pathway for protein export in Saccharomyces cerevisiae." Cleves A.E., Cooper D.N.W., Barondes S.H., Kelly R.B. J. Cell Biol. 133:1017-1026(1996) [PubMed: 8655575] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION. Strain: ATCC 26109 / X2180.
[2]	"The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes." Purnelle B., Coster F., Goffeau A. Yeast 10:1235-1249(1994) [PubMed: 7754713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[4]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U41658 mRNA. Translation: AAC49349.1. Z49480 Genomic DNA. Translation: CAA89500.1. Z49481 Genomic DNA. Translation: CAA89503.1. BK006943 Genomic DNA. Translation: DAA08605.1.
PIR	S61953.
RefSeq	NP_012330.1. NM_001181639.1.
3D structure databases
ProteinModelPortal	Q02820.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q02820. 1 interaction.
Protein family/group databases
TCDB	9.A.27.1.1. non-classical protein exporter (NCPE) family.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJL205C; YJL205C; YJL205C.
GeneID	853225.
KEGG	sce:YJL205C.
NMPDR	fig|4932.3.peg.3293.
Organism-specific databases
CYGD	YJL205c.
SGD	S000003742. NCE101.
Phylogenomic databases
eggNOG	fuNOG13594.
HOGENOM	HBG398807.
OMA	VASYYLY.
OrthoDB	EOG4W9NDV.
Gene expression databases
ArrayExpress	Q02820.
Genevestigator	Q02820.
GermOnline	YJL205C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR024242. NCE101. [Graphical view]
Pfam	PF11654. DUF2665. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	973431.

Entry information

Entry name

NCE1_YEAST

Accession

Primary (citable) accession number: Q02820
Secondary accession number(s): D6VVY9, O00037, O00038

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program