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Q027N4 (Q027N4_SOLUE) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Acid_1783
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Solibacteres › Solibacterales › Solibacteraceae › Candidatus Solibacter

Protein attributes

Sequence length638 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
Q027N4 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 2827EB7338D76B5C

FASTA63869,896
        10         20         30         40         50         60 
MRSPRTPHTN MATILEGIQS PEQVQKLSLP ELDQLAAEIR ERLITVLSNN GGHLGPNLGV 

        70         80         90        100        110        120 
VELTLALHYV FQTPADSLLF DVSHQAYVHK LLTGRQDQFH TIRTPGGLNG FMLRTESPHD 

       130        140        150        160        170        180 
AYGAGHAGTA LSAALGMAVA RDKTGGKEHV IAVAGDAAFT CGITYEALNN IAHHTKRMIV 

       190        200        210        220        230        240 
VLNDNEWSID KNVGAIATYL NKIVTSPRFD YLHDRAGKLV EMVGGEAALR MARRAEEVAK 

       250        260        270        280        290        300 
GMLWPSVIFE ELGLKYFGPI DGHDTATLIK TFEYLKKQDR PVLLHVLTQK GKGFEPAMQK 

       310        320        330        340        350        360 
QKKFHGLGPY DPETGETKPL GRRTYSEVFA DTMVKLADYD PKVVAITAAM PNGTGLDRFQ 

       370        380        390        400        410        420 
PHHPDKYFDV GIAEEHAVLF AAGLAAKGFK PFCAIYSTFL QRAFDPIVHD VCLQNLPVVF 

       430        440        450        460        470        480 
CMDRGGLSAD DGPTHHGLFD ISYLRSVPNL VHMVPKDEDE LADMLFTAMK WNGPIAVRYP 

       490        500        510        520        530        540 
RGLGPGTPVK DVPRAIAVGK AELLQHGEND RVAIFAIGAM VPLAEEIARK LEGEGIAAAV 

       550        560        570        580        590        600 
VNARFTKPID VAMLEFFAGT AEVILTLEDH VLRGGFGSAV LEELSNLGLN TPVVRIGWPD 

       610        620        630 
HFIEHGKQDA LRAKYGFTPE AALEKLRPYL RLRQAQPV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000473 Genomic DNA. Translation: ABJ82773.1.
RefSeqYP_823058.1. NC_008536.1.

3D structure databases

ProteinModelPortalQ027N4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ027N4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4430016.
GenomeReviewsGene locus Acid_1783 in contig CP000473_GR.
KEGGsus:Acid_1783.
NMPDRfig|234267.9.peg.1691.
PATRIC32005773. VBICanSol30224_1864.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1154.
HOGENOMHBG571647.
OMAQYDISYM.
PhylomeDBQ027N4.
ProtClustDBCLSK2319303.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR011766. TPP_enzyme-bd_C.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02775. TPP_enzyme_C. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ027N4_SOLUE
AccessionPrimary (citable) accession number: Q027N4
Entry history
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info