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Q02794 (STD1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Protein STD1
Alternative name(s):
Glucose repression modulator MSN3
Suppressor of fluoride sensitivity 3
Gene names
Name:STD1
Synonyms:MSN3, SFS3
Ordered Locus Names:YOR047C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Potential transcriptional activator. Suppressor of TATA-binding protein (TBP) with a deletion of the nonconserved N-terminus which disrupts normal transcriptional regulation in the cell. Physically interacts with the SNF1 kinase.

Miscellaneous

Present with 238 molecules/cell in log phase SD medium. Ref.5

Sequence similarities

To yeast MTH1.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 444444Protein STD1
PRO_0000072260

Experimental info

Sequence conflict1391E → D in AAA18535. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q02794 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: 888D2D78A72A6507

FASTA44450,261
        10         20         30         40         50         60 
MFVSPPPATA RNQVLGKRKS KRHDENPKNV QPNADTEMTN SVPSIGFNSN LPHNNQEINT 

        70         80         90        100        110        120 
PNHYNLSSNS GNVRSNNNFV TTPPEYADRA RIEIIKRLLP TAGTKPMEVN SNTAENANIQ 

       130        140        150        160        170        180 
HINTPDSQSF VSDHSSSYES SIFSQPSTAL TDITTGSSLI DTKTPKFVTE VTLEDALPKT 

       190        200        210        220        230        240 
FYDMYSPEVL MSDPANILYN GRPKFTKREL LDWDLNDIRS LLIVEQLRPE WGSQLPTVVT 

       250        260        270        280        290        300 
SGINLPQFRL QLLPLSSSDE FIIATLVNSD LYIEANLDRN FKLTSAKYTV ASARKRHEEM 

       310        320        330        340        350        360 
TGSKEPIMRL SKPEWRNIIE NYLLNVAVEA QCRYDFKQKR SEYKRWKLLN SNLKRPDMPP 

       370        380        390        400        410        420 
PSLIPHGFKI HDCTNSGSLL KKALMKNLQL KNYKNDAKTL GAGTQKNVVN KVSLTSEERA 

       430        440 
AIWFQCQTQV YQRLGLDWKP DGMS 

« Hide

References

« Hide 'large scale' references
[1]"Isolation of STD1, a high-copy-number suppressor of a dominant negative mutation in the yeast TATA-binding protein."
Ganster R.W., Shen W., Schmidt M.C.
Mol. Cell. Biol. 13:3650-3659(1993) [PubMed: 8497275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BJ1991.
[2]"Dosage-dependent modulation of glucose repression by MSN3 (STD1) in Saccharomyces cerevisiae."
Hubbard E.J.A., Jiang R., Carlson M.
Mol. Cell. Biol. 14:1972-1978(1994) [PubMed: 8114728] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 204508 / S288c.
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed: 9169874] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L06011 Unassigned DNA. Translation: AAA16951.1.
L21932 Unassigned DNA. Translation: AAA18535.1.
Z74955 Genomic DNA. Translation: CAA99238.1.
BK006948 Genomic DNA. Translation: DAA10829.1.
PIRB48129.
RefSeqNP_014690.1. NM_001183466.1.

3D structure databases

ProteinModelPortalQ02794.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-1300N.
IntActQ02794. 15 interactions.
MINTMINT-388813.
STRINGQ02794.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR047C; YOR047C; YOR047C.
GeneID854212.
KEGGsce:YOR047C.
NMPDRfig|4932.3.peg.5790.

Organism-specific databases

CYGDYOR047c.
SGDS000005573. STD1.

Phylogenomic databases

eggNOGfuNOG05433.
GeneTreeEFGT00050000008554.
HOGENOMHBG756486.
OrthoDBEOG4F4WM3.

Gene expression databases

ArrayExpressQ02794.
GenevestigatorQ02794.
GermOnlineYOR047C. Saccharomyces cerevisiae.

Family and domain databases

ProtoNetSearch...

Other

NextBio976068.

Entry information

Entry nameSTD1_YEAST
AccessionPrimary (citable) accession number: Q02794
Secondary accession number(s): D6W2B3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: January 25, 2012
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD