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Protein

Ubiquinol-cytochrome c reductase iron-sulfur subunit

Gene

petA

Organism
Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.

Catalytic activityi

Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+.

Cofactori

[2Fe-2S] clusterPROSITE-ProRule annotationNote: Binds 1 [2Fe-2S] cluster per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi129 – 1291Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation
Metal bindingi131 – 1311Iron-sulfur (2Fe-2S); via pros nitrogenPROSITE-ProRule annotation
Metal bindingi149 – 1491Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation
Metal bindingi152 – 1521Iron-sulfur (2Fe-2S); via pros nitrogenPROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Protein family/group databases

TCDBi3.E.2.1.1. the photosynthetic reaction center (prc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinol-cytochrome c reductase iron-sulfur subunit (EC:1.10.2.2)
Alternative name(s):
Rieske iron-sulfur protein
Short name:
RISP
Gene namesi
Name:petA
Synonyms:fbcF
OrganismiRhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
Taxonomic identifieri1063 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Ubiquinol-cytochrome c reductase iron-sulfur subunitPRO_0000127764Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi134 ↔ 151PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Protein-protein interaction databases

DIPiDIP-61258N.
STRINGi272943.RSP_1396.

Structurei

Secondary structure

1
187
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi10 – 3627Combined sources
Turni42 – 443Combined sources
Beta strandi50 – 534Combined sources
Beta strandi61 – 677Combined sources
Beta strandi70 – 767Combined sources
Helixi79 – 868Combined sources
Helixi90 – 923Combined sources
Beta strandi100 – 1034Combined sources
Helixi111 – 1144Combined sources
Beta strandi115 – 1173Combined sources
Beta strandi122 – 1265Combined sources
Turni130 – 1323Combined sources
Beta strandi137 – 1415Combined sources
Turni142 – 1454Combined sources
Beta strandi146 – 1494Combined sources
Turni150 – 1534Combined sources
Beta strandi154 – 1563Combined sources
Beta strandi162 – 1665Combined sources
Beta strandi175 – 18612Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FYNX-ray3.20C/F/I/L/O/R1-187[»]
2NUKX-ray1.20A47-187[»]
2NUMX-ray1.50A47-187[»]
2NVEX-ray1.50A47-187[»]
2NVFX-ray1.50A47-187[»]
2NVGX-ray1.35A47-187[»]
2NWFX-ray1.10A47-187[»]
2QJKX-ray3.10C/F/I/L/O/R9-187[»]
2QJPX-ray2.60C/F/I/L9-187[»]
2QJYX-ray2.40C/F/I/L/O/R1-187[»]
ProteinModelPortaliQ02762.
SMRiQ02762. Positions 9-187.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ02762.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini89 – 18597RieskePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 Rieske domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108R5F. Bacteria.
COG0723. LUCA.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERiPTHR10134. PTHR10134. 1 hit.
PfamiPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSiPR00162. RIESKE.
SUPFAMiSSF50022. SSF50022. 1 hit.
TIGRFAMsiTIGR01416. Rieske_proteo. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q02762-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNAEDHAGT RRDFLYYATA GAGAVATGAA VWPLINQMNP SADVQALASI
60 70 80 90 100
FVDVSSVEPG VQLTVKFLGK PIFIRRRTEA DIELGRSVQL GQLVDTNARN
110 120 130 140 150
ANIDAGAEAT DQNRTLDEAG EWLVMWGVCT HLGCVPIGGV SGDFGGWFCP
160 170 180
CHGSHYDSAG RIRKGPAPEN LPIPLAKFID ETTIQLG
Length:187
Mass (Da):19,910
Last modified:February 1, 1994 - v1
Checksum:i575B47EEEECD74D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56157 Genomic DNA. Translation: CAA39623.1.
M18577 Genomic DNA. Translation: AAA26150.1.
PIRiS13868.
RefSeqiWP_002722009.1. NZ_CP012960.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56157 Genomic DNA. Translation: CAA39623.1.
M18577 Genomic DNA. Translation: AAA26150.1.
PIRiS13868.
RefSeqiWP_002722009.1. NZ_CP012960.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FYNX-ray3.20C/F/I/L/O/R1-187[»]
2NUKX-ray1.20A47-187[»]
2NUMX-ray1.50A47-187[»]
2NVEX-ray1.50A47-187[»]
2NVFX-ray1.50A47-187[»]
2NVGX-ray1.35A47-187[»]
2NWFX-ray1.10A47-187[»]
2QJKX-ray3.10C/F/I/L/O/R9-187[»]
2QJPX-ray2.60C/F/I/L9-187[»]
2QJYX-ray2.40C/F/I/L/O/R1-187[»]
ProteinModelPortaliQ02762.
SMRiQ02762. Positions 9-187.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61258N.
STRINGi272943.RSP_1396.

Protein family/group databases

TCDBi3.E.2.1.1. the photosynthetic reaction center (prc) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4108R5F. Bacteria.
COG0723. LUCA.

Miscellaneous databases

EvolutionaryTraceiQ02762.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERiPTHR10134. PTHR10134. 1 hit.
PfamiPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSiPR00162. RIESKE.
SUPFAMiSSF50022. SSF50022. 1 hit.
TIGRFAMsiTIGR01416. Rieske_proteo. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUCRI_RHOSH
AccessioniPrimary (citable) accession number: Q02762
Secondary accession number(s): P72327
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 11, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The Rieske protein is a high potential 2Fe-2S protein.

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.