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Q02654 (COX3_PODAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismPodospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina) [Complete proteome]
Taxonomic identifier515849 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Sordariales › Lasiosphaeriaceae › Podospora ›

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183835

Regions

Transmembrane46 – 6621Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane138 – 16023Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q02654 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: F36727FD791059B4

FASTA26930,231
        10         20         30         40         50         60 
MTNLIRSNFQ DHPFHLVSPS PWPLYTSVSL LNLATSAALS MHNFNNSYYL FFISLILVIS 

        70         80         90        100        110        120 
SMAFWFRDII SEATLLGDHT LAVQKGLNLG VILFIVSEAL FFLAIFWAFF HSSLTPTVEL 

       130        140        150        160        170        180 
GSQWPPIGIE PINPFELPLL NTVILLSSGA TVTYAHHSLI HGERKGALYG SIITILLAII 

       190        200        210        220        230        240 
FTVFQGVEYN VSSFTISDGA FGTCFYFGTG FHGFHVIIGT IFLAVALWRI FAYHLTDNHH 

       250        260 
VGFEGGILYW HFVDVVWLFL YVSIYYWGS

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence, structure, and phylogenetic relationship of the small subunit rRNA coding region of mitochondrial DNA from Podospora anserina."
Cummings D.J., Domenico J.M., Nelson J., Sogin M.L.
J. Mol. Evol. 28:232-241(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete DNA sequence of the mitochondrial genome of Podospora anserina."
Cummings D.J., McNally K.L., Domenico J.M., Matsuura E.T.
Curr. Genet. 17:375-402(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: s.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X55026 Genomic DNA. Translation: CAA38768.1.
X14734 Genomic DNA. Translation: CAA32858.1.
PIRS06029.
RefSeqNP_074915.1. NC_001329.3.

3D structure databases

ProteinModelPortalQ02654.
SMRQ02654. Positions 10-269.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID802433.
KEGGpan:PoanfMp07.

Phylogenomic databases

KOK02262.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_PODAN
AccessionPrimary (citable) accession number: Q02654
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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