Reviewed, UniProtKB/Swiss-Prot Q02608 (RT16_YEAST)

Names and origin

Protein names

Recommended name:
    37S ribosomal protein S16, mitochondrial

Gene names

Name:	MRPS16
Ordered Locus Names:	YPL013C
ORF Names:	LPA4C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subunit structure	Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).
Subcellular location	Mitochondrion.
Sequence similarities	Belongs to the ribosomal protein S16P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mitochondrial translation Ref.2 Inferred by curator. Source: SGD
Cellular component	mitochondrial small ribosomal subunit Ref.2 Inferred from physical interaction. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct structural constituent of ribosome Ref.2 Inferred from physical interaction. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
GTS1	P40956	1	EBI-16281,EBI-7968
TYS1	P36421	1	EBI-16281,EBI-18843

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 121	121	37S ribosomal protein S16, mitochondrial		PRO_0000167326

Sequences

	Sequence		Length	Mass (Da)
	Q02608-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B79B98EE384CDE44	FASTA	121	13,639
	10 20 30 40 50 60 MTCGLVRIRL ARFGRKNSPV YNIVVANSRK ARDAKPIEVL GTYVPVPSPV TKRELKRGVV 70 80 90 100 110 120 PIKDVKLDFD RTKYWIGVGA QPSETVTKLL RKAGILNDAW ATSKNSNVNR KVVFERMETL E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components." Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K. Eur. J. Biochem. 269:5203-5214(2002) [PubMed: 12392552] [Abstract] Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, MASS SPECTROMETRY.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U33335 Genomic DNA. Translation: AAB68092.1.
PIR	S59680.
RefSeq	NP_015312.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4453N.
IntAct	Q02608. 32 interactions.
STRING	Q02608.
Proteomic databases
PeptideAtlas	Q02608.
PRIDE	Q02608.
Genome annotation databases
Ensembl	YPL013C; YPL013C; YPL013C; Saccharomyces cerevisiae. [Genome view]
GeneID	856094.
KEGG	sce:YPL013C.
NMPDR	fig|4932.3.peg.6446.
Organism-specific databases
CYGD	YPL013c.
SGD	S000005934. MRPS16.
Phylogenomic databases
HOGENOM	Q02608.
OMA	ARFGRKH
OrthoDB	EOG9PRV6V
Gene expression databases
ArrayExpress	Q02608.
Genevestigator	Q02608.
GermOnline	YPL013C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000307. Ribosomal_S16. IPR020592. Ribosomal_S16_CS. [Graphical view]
Gene3D	G3DSA:3.30.1320.10. Ribosomal_S16. 1 hit.
PANTHER	PTHR12919. Ribosomal_S16. 1 hit.
Pfam	PF00886. Ribosomal_S16. 1 hit. [Graphical view]
TIGRFAMs	TIGR00002. S16. 1 hit.
PROSITE	PS00732. RIBOSOMAL_S16. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	981128.

Entry information

Entry name

RT16_YEAST

Accession

Primary (citable) accession number: Q02608

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	November 24, 2009
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)