Q02608 (RT16_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
37S ribosomal protein S16, mitochondrial

Gene names

Name:	MRPS16
Ordered Locus Names:	YPL013C
ORF Names:	LPA4C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).
Subcellular location	Mitochondrion Ref.4 Ref.5.
Sequence similarities	Belongs to the ribosomal protein S16P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	mitochondrial translation Inferred by curator Ref.3. Source: SGD
Cellular component	mitochondrial small ribosomal subunit Inferred from physical interaction Ref.3. Source: SGD
Molecular function	structural constituent of ribosome Inferred from physical interaction Ref.3. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
GTS1	P40956	1	EBI-16281,EBI-7968
TYS1	P36421	1	EBI-16281,EBI-18843

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 121	121	37S ribosomal protein S16, mitochondrial		PRO_0000167326

Sequences

	Sequence		Length	Mass (Da)
	Q02608 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B79B98EE384CDE44	FASTA	121	13,639
	10 20 30 40 50 60 MTCGLVRIRL ARFGRKNSPV YNIVVANSRK ARDAKPIEVL GTYVPVPSPV TKRELKRGVV 70 80 90 100 110 120 PIKDVKLDFD RTKYWIGVGA QPSETVTKLL RKAGILNDAW ATSKNSNVNR KVVFERMETL E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components." Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K. Eur. J. Biochem. 269:5203-5214(2002) [PubMed: 12392552] [Abstract] Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, MASS SPECTROMETRY.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Strain: ATCC 76625 / YPH499.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U33335 Genomic DNA. Translation: AAB68092.1. BK006949 Genomic DNA. Translation: DAA11415.1.
PIR	S59680.
RefSeq	NP_015312.1. NM_001183827.1.
3D structure databases
ProteinModelPortal	Q02608.
SMR	Q02608. Positions 5-102.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4453N.
IntAct	Q02608. 30 interactions.
MINT	MINT-572585.
STRING	Q02608.
Proteomic databases
PeptideAtlas	Q02608.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPL013C; YPL013C; YPL013C.
GeneID	856094.
KEGG	sce:YPL013C.
NMPDR	fig|4932.3.peg.6446.
Organism-specific databases
CYGD	YPL013c.
SGD	S000005934. MRPS16.
Phylogenomic databases
eggNOG	fuNOG10104.
GeneTree	EFGT00050000004520.
HOGENOM	HBG410188.
OMA	TRMGKKK.
OrthoDB	EOG498Z9D.
Gene expression databases
ArrayExpress	Q02608.
Genevestigator	Q02608.
GermOnline	YPL013C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000307. Ribosomal_S16. IPR020592. Ribosomal_S16_CS. IPR023803. Ribosomal_S16_dom. [Graphical view]
Gene3D	G3DSA:3.30.1320.10. Ribosomal_S16. 1 hit.
PANTHER	PTHR12919. Ribosomal_S16. 1 hit.
Pfam	PF00886. Ribosomal_S16. 1 hit. [Graphical view]
SUPFAM	SSF54565. Ribosomal_S16. 1 hit.
TIGRFAMs	TIGR00002. S16. 1 hit.
PROSITE	PS00732. RIBOSOMAL_S16. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	981128.

Entry information

Entry name

RT16_YEAST

Accession

Primary (citable) accession number: Q02608
Secondary accession number(s): D6W3Z9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program