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Q02410

- APBA1_HUMAN

UniProt

Q02410 - APBA1_HUMAN

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Protein
Amyloid beta A4 precursor protein-binding family A member 1
Gene
APBA1, MINT1, X11
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.

GO - Molecular functioni

  1. beta-amyloid binding Source: Ensembl
  2. phosphatidylinositol-4,5-bisphosphate binding Source: Ensembl
  3. protein binding Source: IntAct

GO - Biological processi

  1. axon cargo transport Source: ProtInc
  2. cell adhesion Source: ProtInc
  3. gamma-aminobutyric acid secretion Source: Ensembl
  4. glutamate secretion Source: Ensembl
  5. in utero embryonic development Source: Ensembl
  6. intracellular protein transport Source: ProtInc
  7. locomotory behavior Source: Ensembl
  8. multicellular organism growth Source: Ensembl
  9. nervous system development Source: ProtInc
  10. protein complex assembly Source: ProtInc
  11. regulation of gene expression Source: Ensembl
  12. synaptic transmission Source: ProtInc
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Amyloid beta A4 precursor protein-binding family A member 1
Alternative name(s):
Adapter protein X11alpha
Neuron-specific X11 protein
Neuronal Munc18-1-interacting protein 1
Short name:
Mint-1
Gene namesi
Name:APBA1
Synonyms:MINT1, X11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:578. APBA1.

Subcellular locationi

Cytoplasm. Cytoplasmperinuclear region. Nucleus
Note: Only about 5% of the protein is located in the nucleus.2 Publications
Isoform 2 : Golgi apparatus 2 Publications

GO - Cellular componenti

  1. Golgi apparatus Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
  3. perinuclear region of cytoplasm Source: UniProtKB-SubCell
  4. plasma membrane Source: Ensembl
  5. protein complex Source: Ensembl
  6. synaptic vesicle Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi608 – 6081F → V: Diminishes interaction with APP. 1 Publication

Organism-specific databases

PharmGKBiPA24869.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 837837Amyloid beta A4 precursor protein-binding family A member 1
PRO_0000064614Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei263 – 2631Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ02410.
PRIDEiQ02410.

PTM databases

PhosphoSiteiQ02410.

Expressioni

Tissue specificityi

Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen.1 Publication

Gene expression databases

BgeeiQ02410.
CleanExiHS_APBA1.
GenevestigatoriQ02410.

Organism-specific databases

HPAiCAB009338.
HPA019850.

Interactioni

Subunit structurei

Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Both isoform 1 and isoform 2 bind to the cytoplasmic domain of amyloid protein (APP). Interacts (via PDZ 1 and 2 domains) with FSPB. Isoform 2, but not isoform 1, interacts (via its truncated PID domain) with active, GTP-bound RAB6A and RAB6B.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
APPP050673EBI-368690,EBI-77613
PSEN1P497684EBI-368690,EBI-297277
RAB6AP20340-14EBI-9247455,EBI-8851226
RAB6BQ9NRW14EBI-9247455,EBI-1760079

Protein-protein interaction databases

BioGridi106817. 12 interactions.
IntActiQ02410. 11 interactions.
MINTiMINT-153502.
STRINGi9606.ENSP00000265381.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni455 – 4573
Beta strandi459 – 47214
Helixi479 – 49820
Beta strandi516 – 5216
Beta strandi523 – 5308
Turni531 – 5333
Beta strandi536 – 5416
Helixi542 – 5443
Beta strandi545 – 5517
Beta strandi554 – 5596
Beta strandi586 – 5938
Helixi597 – 61620
Beta strandi655 – 6606
Beta strandi669 – 6724
Beta strandi676 – 6794
Beta strandi684 – 6885
Beta strandi690 – 6923
Helixi693 – 6975
Beta strandi705 – 7095
Helixi719 – 7279
Beta strandi730 – 74011
Beta strandi746 – 75611
Beta strandi760 – 7645
Beta strandi767 – 7715
Helixi777 – 7804
Beta strandi786 – 7883
Helixi796 – 7983
Helixi801 – 8099
Beta strandi813 – 8219

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AQCX-ray2.30A/B453-623[»]
1U37NMR-A655-741[»]
1U38NMR-A655-741[»]
1U39NMR-A743-822[»]
1U3BNMR-A655-837[»]
1X11X-ray2.50A/B453-623[»]
1X45NMR-A656-740[»]
1Y7NNMR-A745-823[»]
ProteinModelPortaliQ02410.
SMRiQ02410. Positions 453-837.

Miscellaneous databases

EvolutionaryTraceiQ02410.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini457 – 643187PID
Add
BLAST
Domaini656 – 74287PDZ 1
Add
BLAST
Domaini747 – 82276PDZ 2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni226 – 31489Munc-18-1 binding
Add
BLAST
Regioni373 – 43664LIN-2/CASK binding
Add
BLAST
Regioni626 – 64116Autoinhibitory helix linker By similarity
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi67 – 704Poly-Glu
Compositional biasi294 – 32835Pro-rich
Add
BLAST
Compositional biasi368 – 45285Pro-rich
Add
BLAST

Domaini

Composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
The autoinhibitory helix linker occludes the APP binding site By similarity.
The PID domain, truncated by 11 amino acids, as observed in isoform 2, but not full-length, mediates the interaction with RAB6A and RAB6B (1 Publication).

Sequence similaritiesi

Contains 2 PDZ (DHR) domains.
Contains 1 PID domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG283022.
HOGENOMiHOG000033981.
HOVERGENiHBG050523.
InParanoidiQ02410.
KOiK04531.
OMAiLQEHVYE.
OrthoDBiEOG78PV8H.
PhylomeDBiQ02410.
TreeFamiTF315245.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
2.30.42.10. 2 hits.
InterProiIPR001478. PDZ.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF00595. PDZ. 2 hits.
PF00640. PID. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 2 hits.
SM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 2 hits.
PROSITEiPS50106. PDZ. 2 hits.
PS01179. PID. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q02410-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MNHLEGSAEV EVTDEAAGGE VNESVEADLE HPEVEEEQQQ PPQQQHYVGR    50
HQRGRALEDL RAQLGQEEEE RGECLARSAS TESGFHNHTD TAEGDVIAAA 100
RDGYDAERAQ DPEDESAYAV QYRPEAEEYT EQAEAEHAEA THRRALPNHL 150
HFHSLEHEEA MNAAYSGYVY THRLFHRGED EPYSEPYADY GGLQEHVYEE 200
IGDAPELDAR DGLRLYEQER DEAAAYRQEA LGARLHHYDE RSDGESDSPE 250
KEAEFAPYPR MDSYEQEEDI DQIVAEVKQS MSSQSLDKAA EDMPEAEQDL 300
ERPPTPAGGR PDSPGLQAPA GQQRAVGPAG GGEAGQRYSK EKRDAISLAI 350
KDIKEAIEEV KTRTIRSPYT PDEPKEPIWV MRQDISPTRD CDDQRPMDGD 400
SPSPGSSSPL GAESSSTSLH PSDPVEASTN KESRKSLASF PTYVEVPGPC 450
DPEDLIDGII FAANYLGSTQ LLSDKTPSKN VRMMQAQEAV SRIKMAQKLA 500
KSRKKAPEGE SQPMTEVDLF ISTQRIKVLN ADTQETMMDH PLRTISYIAD 550
IGNIVVLMAR RRMPRSNSQE NVEASHPSQD GKRQYKMICH VFESEDAQLI 600
AQSIGQAFSV AYQEFLRANG INPEDLSQKE YSDLLNTQDM YNDDLIHFSK 650
SENCKDVFIE KQKGEILGVV IVESGWGSIL PTVIIANMMH GGPAEKSGKL 700
NIGDQIMSIN GTSLVGLPLS TCQSIIKGLK NQSRVKLNIV RCPPVTTVLI 750
RRPDLRYQLG FSVQNGIICS LMRGGIAERG GVRVGHRIIE INGQSVVATP 800
HEKIVHILSN AVGEIHMKTM PAAMYRLLTA QEQPVYI 837
Length:837
Mass (Da):92,865
Last modified:October 17, 2006 - v3
Checksum:i29C3620BBC89534B
GO
Isoform 2 (identifier: Q02410-2) [UniParc]FASTAAdd to Basket

Also known as: Mint1_826

The sequence of this isoform differs from the canonical sequence as follows:
     495-505: Missing.

Note: This isoform interacts with RAB6 GTPases.

Show »
Length:826
Mass (Da):91,594
Checksum:iDD7B6C1C6D3D9FE7
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti184 – 1841S → A.
Corresponds to variant rs34788368 [ dbSNP | Ensembl ].
VAR_050664

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei495 – 50511Missing in isoform 2.
VSP_053518Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti164 – 1641A → V in AAA61307. 1 Publication
Sequence conflicti208 – 2081D → H in AAC05304. 1 Publication
Sequence conflicti427 – 4293AST → VPI in AAC05304. 1 Publication
Sequence conflicti427 – 4293AST → VPI in AAA61307. 1 Publication
Sequence conflicti522 – 5221S → L in AAC05304. 1 Publication
Sequence conflicti522 – 5221S → L in AAA61307. 1 Publication
Sequence conflicti563 – 5631M → I in AAC05304. 1 Publication
Sequence conflicti563 – 5631M → I in AAA61307. 1 Publication
Sequence conflicti730 – 7301K → E in AAC05304. 1 Publication
Sequence conflicti730 – 7301K → E in AAA61307. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF029106 mRNA. Translation: AAC05304.1.
AF047347 mRNA. Translation: AAC39766.1.
AL353693, AL355140 Genomic DNA. Translation: CAH74104.1.
AL355140, AL353693 Genomic DNA. Translation: CAI15443.1.
L04953 mRNA. Translation: AAA61307.1.
CCDSiCCDS6630.1. [Q02410-1]
PIRiA47176.
RefSeqiNP_001154.2. NM_001163.3. [Q02410-1]
XP_005252024.1. XM_005251967.1. [Q02410-1]
XP_005252025.1. XM_005251968.1. [Q02410-2]
XP_006717156.1. XM_006717093.1. [Q02410-1]
UniGeneiHs.171939.
Hs.592974.

Genome annotation databases

EnsembliENST00000265381; ENSP00000265381; ENSG00000107282. [Q02410-1]
GeneIDi320.
KEGGihsa:320.
UCSCiuc004ahh.2. human. [Q02410-1]

Polymorphism databases

DMDMi116241250.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF029106 mRNA. Translation: AAC05304.1 .
AF047347 mRNA. Translation: AAC39766.1 .
AL353693 , AL355140 Genomic DNA. Translation: CAH74104.1 .
AL355140 , AL353693 Genomic DNA. Translation: CAI15443.1 .
L04953 mRNA. Translation: AAA61307.1 .
CCDSi CCDS6630.1. [Q02410-1 ]
PIRi A47176.
RefSeqi NP_001154.2. NM_001163.3. [Q02410-1 ]
XP_005252024.1. XM_005251967.1. [Q02410-1 ]
XP_005252025.1. XM_005251968.1. [Q02410-2 ]
XP_006717156.1. XM_006717093.1. [Q02410-1 ]
UniGenei Hs.171939.
Hs.592974.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1AQC X-ray 2.30 A/B 453-623 [» ]
1U37 NMR - A 655-741 [» ]
1U38 NMR - A 655-741 [» ]
1U39 NMR - A 743-822 [» ]
1U3B NMR - A 655-837 [» ]
1X11 X-ray 2.50 A/B 453-623 [» ]
1X45 NMR - A 656-740 [» ]
1Y7N NMR - A 745-823 [» ]
ProteinModelPortali Q02410.
SMRi Q02410. Positions 453-837.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 106817. 12 interactions.
IntActi Q02410. 11 interactions.
MINTi MINT-153502.
STRINGi 9606.ENSP00000265381.

Chemistry

ChEMBLi CHEMBL2097170.

PTM databases

PhosphoSitei Q02410.

Polymorphism databases

DMDMi 116241250.

Proteomic databases

PaxDbi Q02410.
PRIDEi Q02410.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000265381 ; ENSP00000265381 ; ENSG00000107282 . [Q02410-1 ]
GeneIDi 320.
KEGGi hsa:320.
UCSCi uc004ahh.2. human. [Q02410-1 ]

Organism-specific databases

CTDi 320.
GeneCardsi GC09M072042.
HGNCi HGNC:578. APBA1.
HPAi CAB009338.
HPA019850.
MIMi 602414. gene.
neXtProti NX_Q02410.
PharmGKBi PA24869.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG283022.
HOGENOMi HOG000033981.
HOVERGENi HBG050523.
InParanoidi Q02410.
KOi K04531.
OMAi LQEHVYE.
OrthoDBi EOG78PV8H.
PhylomeDBi Q02410.
TreeFami TF315245.

Miscellaneous databases

EvolutionaryTracei Q02410.
GeneWikii APBA1.
GenomeRNAii 320.
NextBioi 1311.
PROi Q02410.
SOURCEi Search...

Gene expression databases

Bgeei Q02410.
CleanExi HS_APBA1.
Genevestigatori Q02410.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
2.30.42.10. 2 hits.
InterProi IPR001478. PDZ.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view ]
Pfami PF00595. PDZ. 2 hits.
PF00640. PID. 1 hit.
[Graphical view ]
SMARTi SM00228. PDZ. 2 hits.
SM00462. PTB. 1 hit.
[Graphical view ]
SUPFAMi SSF50156. SSF50156. 2 hits.
PROSITEi PS50106. PDZ. 2 hits.
PS01179. PID. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis."
    Okamoto M., Suedhof T.C.
    J. Biol. Chem. 272:31459-31464(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion."
    Borg J.-P., Yang Y., De Taddeo-Borg M., Margolis B., Turner R.S.
    J. Biol. Chem. 273:14761-14766(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Brain.
  3. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system."
    Duclos F., Koenig M., Boschert U., Sirugo G., Hen R., Mandel J.-L.
    Proc. Natl. Acad. Sci. U.S.A. 90:109-113(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 130-837 (ISOFORM 1).
    Tissue: Fetal brain.
  5. "The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein."
    Borg J.-P., Ooi J., Levy E., Margolis B.
    Mol. Cell. Biol. 16:6229-6241(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: MUTAGENESIS OF PHE-608.
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-263, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  7. "An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter."
    Lau K.F., Perkinton M.S., Rodriguez L., McLoughlin D.M., Miller C.C.
    NeuroReport 21:761-766(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, INTERACTION WITH FSBP.
  8. Cited for: ALTERNATIVE SPLICING (ISOFORM 2), INTERACTION WITH APP; RAB6A AND RAB6B, SUBCELLULAR LOCATION (ISOFORMS 1 AND 2), TISSUE SPECIFICITY.
  9. "Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain."
    Zhang Z., Lee C.-H., Mandiyan V., Borg J.-P., Margolis B., Schlessinger J., Kuriyan J.
    EMBO J. 16:6141-6150(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 452-617.
  10. "Solution structure of the first PDZ domain of amyloid beta A4 precursor protein-binding family A, member 1."
    RIKEN structural genomics initiative (RSGI)
    Submitted (NOV-2005) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 656-740.

Entry informationi

Entry nameiAPBA1_HUMAN
AccessioniPrimary (citable) accession number: Q02410
Secondary accession number(s): O14914, O60570, Q5VYR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 17, 2006
Last modified: September 3, 2014
This is version 134 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi