SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q02358

- CAPSD_LRVLG

UniProt

Q02358 - CAPSD_LRVLG

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Major capsid protein
Gene
ORF2
Organism
Leishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, 35 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers. The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nacent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm By similarity.
Binds and removes 5' cap structures from cellular mRNA By similarity.

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein
Alternative name(s):
Major coat protein
Gene namesi
Name:ORF2
OrganismiLeishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)
Taxonomic identifieri58103 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesTotiviridaeLeishmaniavirus
Virus hostiLeishmania major [TaxID: 5664]
ProteomesiUP000006721: Genome

Subcellular locationi

Virion Reviewed prediction

GO - Cellular componenti

  1. T=2 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=2 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 741741Major capsid protein
PRO_0000404515Add
BLAST

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR008871. Totivirus_coat.
[Graphical view]
PfamiPF05518. Totivirus_coat. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q02358-1 [UniParc]FASTAAdd to Basket

« Hide

MSDTPNSDKV ACGRKPMFCE IIKLANRKRL ILDTTGERVY DARINYCSTA    50
DATVQADCHI YWRLKLRRTD AVFEEYTGQG YALDTASYPQ QYADIIRGYY 100
SKHVSSALAA NTQHFVNVLA MLRHAGACIA HYCMTGKIDF DILSKKKHKN 150
KEVVTLSSAD SLSFLPHSAL YLPSALRASD PEIFNVLYLL GCACDASIAM 200
DNIANTSGAA KYAMPHYNPL QLSHALHVTI FYMLGLMDSC GYGEDAVLAL 250
TAGLHSVTTV IAHSDEGAIT RDALRELSYT QPYGTMPVPI AGYFQHINVL 300
FTTQPAWDQF AGIWDYVILA TAALVHLSDP GMTVNDVTYP TTLTTKVASV 350
DGRNSDIAAQ MMHSATRFCD IYIENLCLFW GVVANPDGNA SQALLHAFNV 400
VACGTEPNRH LEMNVMAPWY WVESSALFSD YSQFRSPISS AGYGPQSIYG 450
ARLVLAATNS LEFTGEAGDY SAYRFEWTTM RHNPLFNILN KRVGDGLANV 500
DFRLRPFNEW LLEGQPSRRS CDAVGHGTPT ATCNHKTPNR NTVDEFIWGS 550
TSCDLFHPAE LTSYTAVCVR FRNYLSEADG DVRVLNTPTR EVIEGNVVTR 600
CDGIRCLDSN KRIQHVPEVA RRYCMMARYL QARTFGALTI GDDIIRGFDK 650
VDKVVKMHKS NNRLGQMPLI DVTGLCQPMI ETSTARASMT TRIDPNRLAA 700
ATARIELPLA PRCTSSLIPS SDAVPEPEPH VGEPGNGSGC A 741
Length:741
Mass (Da):81,749
Last modified:November 1, 1996 - v1
Checksum:i894BAE24F0189F2E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M92355 Genomic RNA. Translation: AAB50023.1.
PIRiB46171.
RefSeqiNP_041190.1. NC_002063.1.

Genome annotation databases

GeneIDi1446404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M92355 Genomic RNA. Translation: AAB50023.1 .
PIRi B46171.
RefSeqi NP_041190.1. NC_002063.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1446404.

Family and domain databases

InterProi IPR008871. Totivirus_coat.
[Graphical view ]
Pfami PF05518. Totivirus_coat. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiCAPSD_LRVLG
AccessioniPrimary (citable) accession number: Q02358
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi