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Q02358

- CAPSD_LRVLG

UniProt

Q02358 - CAPSD_LRVLG

Protein

Major capsid protein

Gene

ORF2

Organism
Leishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, 35 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers. The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nacent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm By similarity.By similarity
    Binds and removes 5' cap structures from cellular mRNA.By similarity

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Major capsid protein
    Alternative name(s):
    Major coat protein
    Gene namesi
    Name:ORF2
    OrganismiLeishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)
    Taxonomic identifieri58103 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesTotiviridaeLeishmaniavirus
    Virus hostiLeishmania major [TaxID: 5664]
    ProteomesiUP000006721: Genome

    Subcellular locationi

    Virion Curated

    GO - Cellular componenti

    1. T=2 icosahedral viral capsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, T=2 icosahedral capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 741741Major capsid proteinPRO_0000404515Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR008871. Totivirus_coat.
    [Graphical view]
    PfamiPF05518. Totivirus_coat. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q02358-1 [UniParc]FASTAAdd to Basket

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    MSDTPNSDKV ACGRKPMFCE IIKLANRKRL ILDTTGERVY DARINYCSTA    50
    DATVQADCHI YWRLKLRRTD AVFEEYTGQG YALDTASYPQ QYADIIRGYY 100
    SKHVSSALAA NTQHFVNVLA MLRHAGACIA HYCMTGKIDF DILSKKKHKN 150
    KEVVTLSSAD SLSFLPHSAL YLPSALRASD PEIFNVLYLL GCACDASIAM 200
    DNIANTSGAA KYAMPHYNPL QLSHALHVTI FYMLGLMDSC GYGEDAVLAL 250
    TAGLHSVTTV IAHSDEGAIT RDALRELSYT QPYGTMPVPI AGYFQHINVL 300
    FTTQPAWDQF AGIWDYVILA TAALVHLSDP GMTVNDVTYP TTLTTKVASV 350
    DGRNSDIAAQ MMHSATRFCD IYIENLCLFW GVVANPDGNA SQALLHAFNV 400
    VACGTEPNRH LEMNVMAPWY WVESSALFSD YSQFRSPISS AGYGPQSIYG 450
    ARLVLAATNS LEFTGEAGDY SAYRFEWTTM RHNPLFNILN KRVGDGLANV 500
    DFRLRPFNEW LLEGQPSRRS CDAVGHGTPT ATCNHKTPNR NTVDEFIWGS 550
    TSCDLFHPAE LTSYTAVCVR FRNYLSEADG DVRVLNTPTR EVIEGNVVTR 600
    CDGIRCLDSN KRIQHVPEVA RRYCMMARYL QARTFGALTI GDDIIRGFDK 650
    VDKVVKMHKS NNRLGQMPLI DVTGLCQPMI ETSTARASMT TRIDPNRLAA 700
    ATARIELPLA PRCTSSLIPS SDAVPEPEPH VGEPGNGSGC A 741
    Length:741
    Mass (Da):81,749
    Last modified:November 1, 1996 - v1
    Checksum:i894BAE24F0189F2E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M92355 Genomic RNA. Translation: AAB50023.1.
    PIRiB46171.
    RefSeqiNP_041190.1. NC_002063.1.

    Genome annotation databases

    GeneIDi1446404.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M92355 Genomic RNA. Translation: AAB50023.1 .
    PIRi B46171.
    RefSeqi NP_041190.1. NC_002063.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1446404.

    Family and domain databases

    InterProi IPR008871. Totivirus_coat.
    [Graphical view ]
    Pfami PF05518. Totivirus_coat. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiCAPSD_LRVLG
    AccessioniPrimary (citable) accession number: Q02358
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 8, 2011
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3