##gff-version 3
Q02318	UniProtKB	Transit peptide	1	33	.	.	.	Note=Mitochondrion	
Q02318	UniProtKB	Chain	34	531	.	.	.	ID=PRO_0000003618;Note=Sterol 26-hydroxylase%2C mitochondrial	
Q02318	UniProtKB	Region	384	398	.	.	.	Note=Sterol-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q02318	UniProtKB	Binding site	476	476	.	.	.	Note=Axial binding residue	
Q02318	UniProtKB	Modified residue	283	283	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9DBG1	
Q02318	UniProtKB	Modified residue	509	509	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9DBG1	
Q02318	UniProtKB	Modified residue	520	520	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9DBG1	
Q02318	UniProtKB	Natural variant	145	145	.	.	.	ID=VAR_016966;Note=In CTX. G->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12000359;Dbxref=dbSNP:rs72551313,PMID:12000359	
Q02318	UniProtKB	Natural variant	169	169	.	.	.	ID=VAR_061046;Note=A->V;Dbxref=dbSNP:rs59443548	
Q02318	UniProtKB	Natural variant	175	175	.	.	.	ID=VAR_048467;Note=T->M;Dbxref=dbSNP:rs2229381	
Q02318	UniProtKB	Natural variant	395	395	.	.	.	ID=VAR_001303;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:2019602;Dbxref=dbSNP:rs121908096,PMID:2019602	
Q02318	UniProtKB	Natural variant	395	395	.	.	.	ID=VAR_012285;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9790667;Dbxref=dbSNP:rs121908096,PMID:9790667	
Q02318	UniProtKB	Natural variant	405	405	.	.	.	ID=VAR_012286;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9186905;Dbxref=dbSNP:rs121908099,PMID:9186905	
Q02318	UniProtKB	Natural variant	474	474	.	.	.	ID=VAR_012287;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7915755;Dbxref=dbSNP:rs121908097,PMID:7915755	
Q02318	UniProtKB	Natural variant	474	474	.	.	.	ID=VAR_012288;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7915755;Dbxref=dbSNP:rs121908098,PMID:7915755	
Q02318	UniProtKB	Natural variant	479	479	.	.	.	ID=VAR_001304;Note=In CTX%3B impairs sterol 26-hydroxylase activity. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:2019602;Dbxref=dbSNP:rs72551322,PMID:2019602	
Q02318	UniProtKB	Mutagenesis	240	240	.	.	.	Note=Impairs sterol 26-hydroxylase activity%3B when associated with A-244 and A-248. F->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	240	240	.	.	.	Note=Impairs sterol 26-hydroxylase activity. F->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	244	244	.	.	.	Note=Impairs sterol 26-hydroxylase activity%3B when associated with A-240 and A-248. I->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	244	244	.	.	.	Note=Impairs sterol 26-hydroxylase activity. I->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	248	248	.	.	.	Note=Impairs sterol 26-hydroxylase activity%3B when associated with A-240 and A-244. F->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	248	248	.	.	.	Note=Impairs sterol 26-hydroxylase activity%3B confers demethylase activity. F->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	268	268	.	.	.	Note=Reduces sterol 26-hydroxylase activity. W->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Mutagenesis	271	271	.	.	.	Note=Reduces sterol 26-hydroxylase activity. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11412116;Dbxref=PMID:11412116	
Q02318	UniProtKB	Sequence conflict	20	25	.	.	.	Note=LCPHGA->SAPTG;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q02318	UniProtKB	Sequence conflict	171	171	.	.	.	Note=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q02318	UniProtKB	Sequence conflict	359	359	.	.	.	Note=E->K;Ontology_term=ECO:0000305;evidence=ECO:0000305