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Q02226 (COXT_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 2, mitochondrial
EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide II
Gene names
Name:COX2
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Glycine

Protein attributes

Sequence length394 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Cofactor

Copper A.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide‹1 – ?119›119Mitochondrion Potential
Chain?120 – 394275Cytochrome c oxidase subunit 2, mitochondrial
PRO_0000006043

Regions

Topological domain120 – 18162Mitochondrial intermembrane Potential
Transmembrane182 – 19817Helical; Potential
Topological domain199 – 22628Mitochondrial matrix Potential
Transmembrane227 – 24317Helical; Potential
Topological domain244 – 394151Mitochondrial intermembrane Potential

Sites

Metal binding3271Copper A Probable
Metal binding3621Copper A Probable
Metal binding3661Copper A Probable
Metal binding3701Copper A Probable

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q02226 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: CDE7AE60D38F3C0B

FASTA39444,333
        10         20         30         40         50         60 
ILCPLEAFIV QHILTISVMG LLSCFRSTVL RKCSKGSSGM SRFLYTNNFQ RNLISSGGNE 

        70         80         90        100        110        120 
SYYGYFNRRS YTSLYMGTGT VGGITSARIR VPNVGCEGFM CSSHLSITQR NSRLIHSTSK 

       130        140        150        160        170        180 
IVPNSEIQNI TTEMVKTPEV SRWMDQVIPT IAPCDAAEPW QLGFQDAATP IMQGIIDLHH 

       190        200        210        220        230        240 
DIFFFVIQIG VFVSWVLLRA LWHFRSKMNP IPQRIVHGTT IEILWTIFPS VILMFIAIPS 

       250        260        270        280        290        300 
FALLYSMDDI VVDPAITIKA IGHQWYWTYE YSDYNNSDEQ SLAFDSYMIP EDDLELGQLR 

       310        320        330        340        350        360 
LLEVDNRVVV PAKTHLRVII TSADVLHSWA VPSLGVKCDA VPGRLNQIST FIQREGVYYG 

       370        380        390 
QCSEICGTNH AFMPIVIEAV STKDYGSWVS SQVN

« Hide

References

[1]"Silent mitochondrial and active nuclear genes for subunit 2 of cytochrome c oxidase (cox2) in soybean: evidence for RNA-mediated gene transfer."
Covello P.S., Gray M.W.
EMBO J. 11:3815-3820(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Williams.
Tissue: Leaf and Shoot.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z11980 Genomic DNA. Translation: CAA78032.1.
PIRS28027.

3D structure databases

ProteinModelPortalQ02226.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Gene expression databases

GenevestigatorQ02226.

Family and domain databases

Gene3D1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProIPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR014222. Cyt_c_oxidase_su2.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view]
PfamPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
SUPFAMSSF49503. Cupredoxin. 1 hit.
SSF81464. Cyt_c_oxidase_II-like_TM. 1 hit.
TIGRFAMsTIGR02866. CoxB. 1 hit.
PROSITEPS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOXT_SOYBN
AccessionPrimary (citable) accession number: Q02226
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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