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Q02226

- COXT_SOYBN

UniProt

Q02226 - COXT_SOYBN

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Protein

Cytochrome c oxidase subunit 2, mitochondrial

Gene
COX2
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Cofactori

Copper A.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi327 – 3271Copper A Inferred
Metal bindingi362 – 3621Copper A Inferred
Metal bindingi366 – 3661Copper A Inferred
Metal bindingi370 – 3701Copper A Inferred

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2, mitochondrial (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide II
Gene namesi
Name:COX2
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini120 – 18162Mitochondrial intermembrane Reviewed predictionAdd
BLAST
Transmembranei182 – 19817Helical; Reviewed predictionAdd
BLAST
Topological domaini199 – 22628Mitochondrial matrix Reviewed predictionAdd
BLAST
Transmembranei227 – 24317Helical; Reviewed predictionAdd
BLAST
Topological domaini244 – 394151Mitochondrial intermembrane Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
  3. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei‹1 – ?119›119Mitochondrion Reviewed predictionAdd
BLAST
Chaini?120 – 394275Cytochrome c oxidase subunit 2, mitochondrialPRO_0000006043Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ02226.

Structurei

3D structure databases

ProteinModelPortaliQ02226.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR014222. Cyt_c_oxidase_su2.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR02866. CoxB. 1 hit.
PROSITEiPS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q02226-1 [UniParc]FASTAAdd to Basket

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ILCPLEAFIV QHILTISVMG LLSCFRSTVL RKCSKGSSGM SRFLYTNNFQ    50
RNLISSGGNE SYYGYFNRRS YTSLYMGTGT VGGITSARIR VPNVGCEGFM 100
CSSHLSITQR NSRLIHSTSK IVPNSEIQNI TTEMVKTPEV SRWMDQVIPT 150
IAPCDAAEPW QLGFQDAATP IMQGIIDLHH DIFFFVIQIG VFVSWVLLRA 200
LWHFRSKMNP IPQRIVHGTT IEILWTIFPS VILMFIAIPS FALLYSMDDI 250
VVDPAITIKA IGHQWYWTYE YSDYNNSDEQ SLAFDSYMIP EDDLELGQLR 300
LLEVDNRVVV PAKTHLRVII TSADVLHSWA VPSLGVKCDA VPGRLNQIST 350
FIQREGVYYG QCSEICGTNH AFMPIVIEAV STKDYGSWVS SQVN 394
Length:394
Mass (Da):44,333
Last modified:October 1, 1993 - v1
Checksum:iCDE7AE60D38F3C0B
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11980 Genomic DNA. Translation: CAA78032.1.
PIRiS28027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11980 Genomic DNA. Translation: CAA78032.1 .
PIRi S28027.

3D structure databases

ProteinModelPortali Q02226.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Genevestigatori Q02226.

Family and domain databases

Gene3Di 1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProi IPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR014222. Cyt_c_oxidase_su2.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view ]
Pfami PF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsi TIGR02866. CoxB. 1 hit.
PROSITEi PS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Silent mitochondrial and active nuclear genes for subunit 2 of cytochrome c oxidase (cox2) in soybean: evidence for RNA-mediated gene transfer."
    Covello P.S., Gray M.W.
    EMBO J. 11:3815-3820(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Williams.
    Tissue: Leaf and Shoot.

Entry informationi

Entry nameiCOXT_SOYBN
AccessioniPrimary (citable) accession number: Q02226
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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