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Protein

C protein alpha-antigen

Gene

bca

Organism
Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in both virulence and immunity.

Miscellaneous

Identical repeating units define protective epitopes and may play a role in generating phenotypic and genotypic diversity.

GO - Biological processi

Keywordsi

Biological processVirulence

Enzyme and pathway databases

BioCyciSAGA205921:G1G54-533-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
C protein alpha-antigen
Gene namesi
Name:bca
Ordered Locus Names:SAK_0517
OrganismiStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Taxonomic identifieri205921 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

  • cell wall PROSITE-ProRule annotation; Peptidoglycan-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 41Add BLAST41
ChainiPRO_000000559742 – 990C protein alpha-antigenAdd BLAST949
PropeptideiPRO_0000005598991 – 1020Removed by sortasePROSITE-ProRule annotationAdd BLAST30

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei990Pentaglycyl murein peptidoglycan amidated threoninePROSITE-ProRule annotation1

Keywords - PTMi

Peptidoglycan-anchor

Proteomic databases

PRIDEiQ02192

Structurei

Secondary structure

11020
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi63 – 66Combined sources4
Turni71 – 73Combined sources3
Beta strandi78 – 82Combined sources5
Helixi83 – 87Combined sources5
Helixi93 – 96Combined sources4
Beta strandi97 – 99Combined sources3
Beta strandi104 – 111Combined sources8
Beta strandi114 – 118Combined sources5
Helixi119 – 121Combined sources3
Beta strandi126 – 135Combined sources10
Beta strandi139 – 141Combined sources3
Beta strandi147 – 149Combined sources3
Beta strandi151 – 159Combined sources9
Helixi162 – 175Combined sources14
Helixi182 – 201Combined sources20
Helixi206 – 220Combined sources15

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YWMX-ray1.86A52-225[»]
2O0IX-ray3.10157-225[»]
ProteinModelPortaliQ02192
SMRiQ02192
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ02192

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni227 – 9649 X 82 AA tandem repeatsAdd BLAST738

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi987 – 991LPXTG sorting signalPROSITE-ProRule annotation5

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

HOGENOMiHOG000095184
OMAiGKDQQVN

Family and domain databases

Gene3Di1.20.1270.150, 1 hit
2.60.500.10, 1 hit
InterProiView protein in InterPro
IPR038335 ACP_C_sf
IPR038544 ACP_N_sf
IPR035327 AlphaC_C
IPR014933 AlphaC_N
IPR019948 Gram-positive_anchor
IPR019950 M_anchor
IPR012706 Rib_alpha_Esp
IPR005877 YSIRK_signal_dom
PfamiView protein in Pfam
PF17480 AlphaC_C, 1 hit
PF08829 AlphaC_N, 1 hit
PF00746 Gram_pos_anchor, 1 hit
PF04650 YSIRK_signal, 1 hit
PRINTSiPR00015 GPOSANCHOR
TIGRFAMsiTIGR02331 rib_alpha, 9 hits
TIGR01168 YSIRK_signal, 1 hit
PROSITEiView protein in PROSITE
PS50847 GRAM_POS_ANCHORING, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q02192-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRRSKNNSY DTSQTKQRFS IKKFKFGAAS VLIGLSFLGG VTQGNLNIFE
60 70 80 90 100
ESIVAASTIP GSAATLNTSI TKNIQNGNAY IDLYDVKLGK IDPLQLIVLE
110 120 130 140 150
QGFTAKYVFR QGTKYYGDVS QLQSTGRASL TYNIFGEDGL PHVKTDGQID
160 170 180 190 200
IVSVALTIYD STTLRDKIEE VRTNANDPKW TEESRTEVLT GLDTIKTDID
210 220 230 240 250
NNPKTQTDID SKIVEVNELE KLLVLSVPDK DKYDPTGGET TVPQGTPVSD
260 270 280 290 300
KEITDLVKIP DGSKGVPTVV GDRPDTNVPG DHKVTVEVTY PDGTKDTVEV
310 320 330 340 350
TVHVTPKPVP DKDKYDPTGG ETTVPQGTPV SDKEITDLVK IPDGSKGVPT
360 370 380 390 400
VVGDRPDTNV PGDHKVTVEV TYPDGTKDTV EVTVHVTPKP VPDKDKYDPT
410 420 430 440 450
GGETTVPQGT PVSDKEITDL VKIPDGSKGV PTVVGDRPDT NVPGDHKVTV
460 470 480 490 500
EVTYPDGTKD TVEVTVHVTP KPVPDKDKYD PTGGETTVPQ GTPVSDKEIT
510 520 530 540 550
DLVKIPDGSK GVPTVVGDRP DTNVPGDHKV TVEVTYPDGT KDTVEVTVHV
560 570 580 590 600
TPKPVPDKDK YDPTGGETTV PQGTPVSDKE ITDLVKIPDG SKGVPTVVGD
610 620 630 640 650
RPDTNVPGDH KVTVEVTYPD GTKDTVEVTV HVTPKPVPDK DKYDPTGGET
660 670 680 690 700
TVPQGTPVSD KEITDLVKIP DGSKGVPTVV GDRPDTNVPG DHKVTVEVTY
710 720 730 740 750
PDGTKDTVEV TVHVTPKPVP DKDKYDPTGG ETTVPQGTPV SDKEITDLVK
760 770 780 790 800
IPDGSKGVPT VVGDRPDTNV PGDHKVTVEV TYPDGTKDTV EVTVHVTPKP
810 820 830 840 850
VPDKDKYDPT GGETTVPQGT PVSDKEITDL VKIPDGSKGV PTVVGDRPDT
860 870 880 890 900
NVPGDHKVTV EVTYPDGTKD TVEVTVHVTP KPVPDKDKYD PTGGETTVPQ
910 920 930 940 950
GTPVSDKEIT DLVKIPDGSK GVPTVVGDRP DTNVPGDHKV TVEVTYPDGT
960 970 980 990 1000
KDTVEVTVHV TPKPVPDKDK YDPTGKAQQV NGKGNKLPAT GENATPFFNV
1010 1020
AALTIISSVG LLSVSKKKED
Length:1,020
Mass (Da):108,705
Last modified:June 1, 1994 - v1
Checksum:i78035594FA190D5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M97256 Genomic DNA Translation: AAA26848.1
CP000114 Genomic DNA Translation: ABA45154.1
RefSeqiWP_000489955.1, NC_007432.1

Genome annotation databases

EnsemblBacteriaiABA45154; ABA45154; SAK_0517
KEGGisak:SAK_0517

Entry informationi

Entry nameiBCA_STRA1
AccessioniPrimary (citable) accession number: Q02192
Secondary accession number(s): Q3K2V1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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