SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q02079

- LAC3_THACU

UniProt

Q02079 - LAC3_THACU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Laccase-3
Gene
LCC3
Organism
Thanatephorus cucumeris (Black scurf of potato) (Rhizoctonia solani)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products Inferred.

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi82 – 821Copper 1; type 2 By similarity
Metal bindingi84 – 841Copper 2; type 3 By similarity
Metal bindingi127 – 1271Copper 2; type 3 By similarity
Metal bindingi129 – 1291Copper 3; type 3 By similarity
Metal bindingi470 – 4701Copper 4; type 1 By similarity
Metal bindingi473 – 4731Copper 1; type 2 By similarity
Metal bindingi475 – 4751Copper 3; type 3 By similarity
Metal bindingi522 – 5221Copper 3; type 3 By similarity
Metal bindingi523 – 5231Copper 4; type 1 By similarity
Metal bindingi524 – 5241Copper 2; type 3 By similarity
Metal bindingi528 – 5281Copper 4; type 1 By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-3 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 3
Diphenol oxidase 3
Urishiol oxidase 3
Gene namesi
Name:LCC3
OrganismiThanatephorus cucumeris (Black scurf of potato) (Rhizoctonia solani)
Taxonomic identifieri107832 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesCantharellalesCeratobasidiaceaeThanatephorus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 Reviewed prediction
Add
BLAST
Chaini19 – 572554Laccase-3
PRO_0000002937Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi182 – 1821N-linked (GlcNAc...) Reviewed prediction
Glycosylationi228 – 2281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi294 – 2941N-linked (GlcNAc...) Reviewed prediction
Glycosylationi367 – 3671N-linked (GlcNAc...) Reviewed prediction
Glycosylationi405 – 4051N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Tissue specificityi

In mycelia, at a lower level than LCC4.

Interactioni

Subunit structurei

Homodimer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ02079.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 145125Plastocyanin-like 1
Add
BLAST
Domaini157 – 304148Plastocyanin-like 2
Add
BLAST
Domaini422 – 540119Plastocyanin-like 3
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q02079-1 [UniParc]FASTAAdd to Basket

« Hide

MARTTFLVSV SLFVSAVLAR TVEYNLKISN GKIAPDGVER DATLVNGGYP    50
GPLIFANKGD TLKVKVQNKL TNPDMYRTTS IHWHGLLQHR NADDDGPAFV 100
TQCPIVPQAS YTYTMPLGDQ TGTYWYHSHL SSQYVDGLRG PLVIYDPKDP 150
HRRLYDIDDE KTVLIIGDWY HTSSKAILAT GNITLQQPDS ATINGKGRFD 200
PDNTPANPNT LYTLKVKRGK RYRLRVINSS AIASFRMSIQ GHKMTVIAAD 250
GVSTKPYQVD SFDILAGQRI DAVVEANQEP DTYWINAPLT NVANKTAQAL 300
LIYEDDRRPY HPPKGPYRKW SVSEAIIKYW KHKHGRGLLS GHGGLKARMM 350
EGSLHLHGRR DIVKRQNETT TVVMDETKLV PLEHPGAACG SKPADLVIDL 400
TFGVNFTTGH WMINGIPHKS PDMPTLLKIL TDTDGVTESD FTQPEHTIIL 450
PKNKCVEFNI KGNSGLGIVH PIHLHGHTFD VVQFGNNPPN YVNPPRRDVV 500
GATDEGVRFQ FKTDNPGPWF LHCHIDWHLE EGFAMVFAEA PEAIKGGPKS 550
VPVDRQWKDL CRKYGSLPAG FL 572
Length:572
Mass (Da):63,747
Last modified:November 1, 1996 - v1
Checksum:iDF1E2AF9FF108CE4
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti159 – 1591D → N.
Natural varianti359 – 3591R → H.
Natural varianti418 – 4181H → Y.
Natural varianti448 – 4481I → V.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z54215 Genomic DNA. Translation: CAA90942.1.
PIRiS68119.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z54215 Genomic DNA. Translation: CAA90942.1 .
PIRi S68119.

3D structure databases

ProteinModelPortali Q02079.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 3 hits.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The identification and characterization of four laccases from the plant pathogenic fungus Rhizoctonia solani."
    Wahleithner J.A., Xu F., Brown K.M., Brown S.H., Golightly E.J., Halkier T., Kauppinen S., Pederson A., Schneider P.
    Curr. Genet. 29:395-403(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: R22 / IMI 358730 / AG-6.

Entry informationi

Entry nameiLAC3_THACU
AccessioniPrimary (citable) accession number: Q02079
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi