Reviewed, UniProtKB/Swiss-Prot Q02066 (AAIP_WHEAT)

Names and origin

Protein names	Recommended name:     Abscisic acid-inducible protein kinase     EC=2.7.11.1
Organism	Triticum aestivum (Wheat)
Taxonomic identifier	4565 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	332 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Involved in water-stress responses.
Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Induction	By abscisic acid (ABA) and dehydration.
Post-translational modification	Autophosphorylated Potential.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain.

Ontologies

Keywords
Biological process	Stress response
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro response to osmotic stress Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 332	›332	Abscisic acid-inducible protein kinase		PRO_0000085588
Regions
	Domain	‹1 – 250	›250	Protein kinase
	Nucleotide binding	‹1 – 8	›8	ATP By similarity
Sites
	Active site	113	1	Proton acceptor By similarity
	Binding site	23	1	ATP By similarity
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q02066-1 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: E19ACAE1C0F0CE37	FASTA	332	37,516
	10 20 30 40 50 60 GSGNFGVAKL VRDVRTKEHF AVKFIERGHK IDEHVQREIM NHRSLKHPNI IRFKEVVLTP 70 80 90 100 110 120 THLAIVMEYA SGGELFQRIC NAGRFSEDEG RFFFQQLISG VSYCHSMQVC HRDLKLENTL 130 140 150 160 170 180 LDGSVAPRLK ICDFGYSKSS VLHSQPKSTV GTPAYIAPEV LSRREYDGKV ADVWSCGVTL 190 200 210 220 230 240 YVMLVGAYPF EDPDEPRNFR KTITRILSVQ YSVPDYVRVS MDCIHLLSRI FVGNPQQRIT 250 260 270 280 290 300 IPEIKNHPWF LKRLPVEMTD EYQRSMQLAD MNTPSQSLEE AMAIIQEAQK PGDNALGVAG 310 320 330 QVACLGSMDL DDIDFDIDDI DVESSGDFVC PL

References

[1]	"Isolation of a wheat cDNA clone for an abscisic acid-inducible transcript with homology to protein kinases." Anderberg R.J., Walker-Simmons M.K. Proc. Natl. Acad. Sci. U.S.A. 89:10183-10187(1992) [PubMed: 1438207] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Brevor. Tissue: Seed.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M94726 mRNA. Translation: AAA96325.1.
PIR	A46408.
UniGene	Ta.2551
3D structure databases
HSSP	HSSP built from PDB template 1GZK based on UniProtKB P31751.
ModBase	Search...
Organism-specific databases
Gramene	Q02066.
Enzyme and pathway databases
BRENDA	2.7.11.1. 253.
Family and domain databases
InterPro	IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_pkinase-rel. IPR015740. Ser/Thr_Kinase-like_plant. IPR008271. Ser_thr_pkin_AS. IPR002290. Ser_thr_pkinase. [Graphical view]
PANTHER	PTHR22982:SF58. S/T_plantPK. 1 hit.
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
ProDom	PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. Partial match. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AAIP_WHEAT

Accession

Primary (citable) accession number: Q02066

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	June 16, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)