Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q02002

- TRPF_LACLA

UniProt

Q02002 - TRPF_LACLA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciLLAC272623:GHSH-1563-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:LL1466
ORF Names:L0050
OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifieri272623 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000002196: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154359Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272623.L0050.

Structurei

3D structure databases

ProteinModelPortaliQ02002.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 198198N-(5'-phosphoribosyl)anthranilate isomeraseAdd
BLAST

Sequence similaritiesi

In the N-terminal section; belongs to the TrpF family.Curated
To B.subtilis YnaI in the C-terminal section.Curated

Phylogenomic databases

eggNOGiCOG0135.
KOiK01817.
OMAiNIDYHEL.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q02002-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIKICGLST KEAVDTAVES GVTHLGFILS PSKRQVAPEK ILQITNDVPK
60 70 80 90 100
TVKKVGVFVD EPIDFVKKAI QVAQLDLVQL HGNEDMNYIN QLDISVIKAI
110 120 130 140 150
RPDQEFKEYE DVILLFDSPQ AGSGQAFDWD SLVTSGLKNK FFIAGGLNPE
160 170 180 190 200
NVAAAIQHFP NAYGVDVSSG VETDGIKNLT KIKNFVQNAS LASSKQLFIE
210 220 230 240 250
FLRITKKLNE NKIIPYLMGS LAVEQIINFP TNPDDIDIQL KTSDFENFEQ
260 270 280 290 300
LTSLMEKLGY QLIDLHEHKF EKASIHVGFA SVETLKNYAG VDYLTIQQER
310 320 330 340 350
MENGEKYHLP NVEQSLKIYE AAKRDEWRGG KQKDSFIFDE LIKEQKRNDN

E
Length:351
Mass (Da):39,586
Last modified:April 1, 1993 - v1
Checksum:i698A3934C9EFD89F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M87483 Genomic DNA. Translation: AAA25227.1.
AE005176 Genomic DNA. Translation: AAK05564.1.
PIRiS35128.
RefSeqiNP_267622.1. NC_002662.1.
WP_003130430.1. NC_002662.1.

Genome annotation databases

EnsemblBacteriaiAAK05564; AAK05564; L0050.
GeneIDi1115123.
KEGGilla:L0050.
PATRICi22295338. VBILacLac136773_1576.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M87483 Genomic DNA. Translation: AAA25227.1 .
AE005176 Genomic DNA. Translation: AAK05564.1 .
PIRi S35128.
RefSeqi NP_267622.1. NC_002662.1.
WP_003130430.1. NC_002662.1.

3D structure databases

ProteinModelPortali Q02002.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272623.L0050.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK05564 ; AAK05564 ; L0050 .
GeneIDi 1115123.
KEGGi lla:L0050.
PATRICi 22295338. VBILacLac136773_1576.

Phylogenomic databases

eggNOGi COG0135.
KOi K01817.
OMAi NIDYHEL.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci LLAC272623:GHSH-1563-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Tryptophan biosynthesis genes in Lactococcus lactis subsp. lactis."
    Bardowski J., Ehrlich S.D., Chopin A.
    J. Bacteriol. 174:6563-6570(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: IL1403.
  2. "The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
    Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
    Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IL1403.

Entry informationi

Entry nameiTRPF_LACLA
AccessioniPrimary (citable) accession number: Q02002
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: October 1, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3