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Q01ZH3 (Q01ZH3_SOLUE) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA gyrase subunit A HAMAP MF_01897
EC=5.99.1.3 HAMAP MF_01897
Gene names
Name:gyrA HAMAP MF_01897
Ordered Locus Names:Acid_3975
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Solibacteres › Solibacterales › Solibacteraceae › Candidatus Solibacter

Protein attributes

Sequence length824 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. SAAS SAAS006691 HAMAP MF_01897

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS006691 HAMAP MF_01897

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01897

Subcellular location

Cytoplasm By similarity SAAS SAAS006691 HAMAP MF_01897.

Sequence similarities

Belongs to the topoisomerase GyrA/ParC subunit family. HAMAP MF_01897

Sequences

Sequence LengthMass (Da)Tools
Q01ZH3 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 5CE60D6E21F83E78

FASTA82491,993
        10         20         30         40         50         60 
MGGGDGGRRN MIPVNIEDEM KQSYLDYAMS VIVGRALPDI RDGLKPVHRR ILYGMHEMGL 

        70         80         90        100        110        120 
APNRPTTKSA KITGQVMGKY HPHGDSAIYD SLVRMAQPFA MRYPLVDGQG NFGSVDGDPP 

       130        140        150        160        170        180 
AAMRYTEARL SKFATALLED IDKETVDFKP NYDDTESEPE VLPTRVPNLL VNGSSGIAVG 

       190        200        210        220        230        240 
MATNIPPHNL TEIINATIHL IQHPTANLAK IMEFVQGPDF PTGGFILGRQ GILDAFIRGR 

       250        260        270        280        290        300 
GQLKLRAKAA IEKMGKDREQ IIVTEIPYQV NKSRLIEAAS ALVNEKKLEG IGDIRDESDR 

       310        320        330        340        350        360 
DGMRIVFELK RGEQAEVILN NLYKHTQLQV GFGIIMLSIV NGQPRELGLV DMIKHFIDHR 

       370        380        390        400        410        420 
IEVVRRRTEY ELRKARDREH ILLGFQKALD HLDEVIRLIR ASKSPKDARD SLITTFQFSD 

       430        440        450        460        470        480 
KQAQAIIELQ LQRLTGMERQ KILDELGEIQ RRIAEYVEIL GSDKVLRDLI IKELKEVQKN 

       490        500        510        520        530        540 
YGDERRTQII EDTGEIRLED LVAVEDVAIT VTRGGYLKRT SVDTYRRQTR GGKGRIGMGT 

       550        560        570        580        590        600 
RAEDFVERLI VASTHSYLLI FTTRGRVYWL KAYEIPDATT IGKGKHLTNL INLQGDEEAK 

       610        620        630        640        650        660 
AFLSVKDFVA NQYIVMVTKH GVIKKSELTE FDNPLSRGII AVSLDEGDEL IGAKITMGDN 

       670        680        690        700        710        720 
YIFLGSHEGQ AIRFREEDVR AMGRQARGVR AMSLADGDYL VGMEVVEKDG LILSIAENGY 

       730        740        750        760        770        780 
GKRTPLEDYR LTSRGGKGVI NMKTTNKTGR VVGILSVKED SELMIVSQNG KMIRIESSTI 

       790        800        810        820 
RQAGRSTQGV RLVNLEPDDK VAAASVIPES DVVPDDGQET LPVQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000473 Genomic DNA. Translation: ABJ84942.1.
RefSeqYP_825227.1. NC_008536.1.

3D structure databases

ProteinModelPortalQ01ZH3.
SMRQ01ZH3. Positions 33-489.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ01ZH3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4427801.
GenomeReviewsGene locus Acid_3975 in contig CP000473_GR.
KEGGsus:Acid_3975.
NMPDRfig|234267.9.peg.3778.
PATRIC32010392. VBICanSol30224_4161.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0188.
HOGENOMHBG635183.
OMATGRGRIY.
PhylomeDBQ01ZH3.
ProtClustDBPRK05560.

Family and domain databases

HAMAPMF_01897. GyrA.
[Tree]
InterProIPR005743. GyrA.
IPR006691. GyrA/parC_pinwhl.
IPR002205. Topo_IIA_A/C.
IPR013758. Topo_IIA_A/C_ab.
IPR013757. Topo_IIA_A_a.
IPR013760. Topo_IIA_cen.
[Graphical view]
Gene3DG3DSA:3.90.199.10. Topo_IIA_A/C_ab. 1 hit.
G3DSA:1.10.268.10. Topo_IIA_A_a. 1 hit.
KOK02469.
PfamPF03989. DNA_gyraseA_C. 6 hits.
PF00521. DNA_topoisoIV. 1 hit.
[Graphical view]
SMARTSM00434. TOP4c. 1 hit.
[Graphical view]
SUPFAMSSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01063. GyrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ01ZH3_SOLUE
AccessionPrimary (citable) accession number: Q01ZH3
Entry history
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info