ID   Q01XW9_SOLUE            Unreviewed;       885 AA.
AC   Q01XW9;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=Acid_4535 {ECO:0000313|EMBL:ABJ85496.1};
OS   Solibacter usitatus (strain Ellin6076).
OC   Bacteria; Acidobacteriota; Terriglobia; Bryobacterales; Solibacteraceae;
OC   Solibacter.
OX   NCBI_TaxID=234267 {ECO:0000313|EMBL:ABJ85496.1};
RN   [1] {ECO:0000313|EMBL:ABJ85496.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ellin6076 {ECO:0000313|EMBL:ABJ85496.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Janssen P.H., Kuske C.R., Richardson P.;
RT   "Complete sequence of Solibacter usitatus Ellin6076.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; CP000473; ABJ85496.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q01XW9; -.
DR   STRING; 234267.Acid_4535; -.
DR   KEGG; sus:Acid_4535; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_012906_0_0_0; -.
DR   InParanoid; Q01XW9; -.
DR   OrthoDB; 100367at2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 2.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:ABJ85496.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU10141};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABJ85496.1};
KW   Transferase {ECO:0000313|EMBL:ABJ85496.1}.
FT   DOMAIN          12..284
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   BINDING         41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   885 AA;  94544 MW;  E86D8A414647BCA9 CRC64;
     MPLKPGARLG NYEIVAAIGA GGMGEVYRAR DARLGREVAI KVLPEAFARD AERMLRFEQE
     ARAVAALNHP NVLSVFDIGT QDGVPYLVSE LLEGESLRDV LRTGPITSRK AVEYARQIAD
     GLAAAHEKKI VHRDLKPENL FLSGGGRLKI LDFGLAKMPV TESAAAGVDA ATATIVAVTS
     PGVVMGTTGY MAPEQVRGDA VDHRADIFSF GATLYEMLTG KRAFQGDSSI ETLNAILKED
     PPEFDSEKLH VSPGLERIVR HCLEKRPGER FQSARDLTFA LSALSDPSGA VKARPAGARV
     GEWRYAAVAA IAALLGAGIG FWAVRRPEPA DRTEFSIAVS GEVNHLAISR DGKWLAYVSP
     GVSDAIPTVY VQRVGSPSVR AIQGSEGGTY PFWSPDNQYV AFFANGKLRK APLAGGNPQT
     VTTVGIAPRG GSWGSKGVIL YSPDSGGPLW RVNADGSGAR PATKMLSSTE SSHRWPLFLA
     DGDHFLMFGG NFSEVQDNAN AIHLGSLSNS KSTPLVNARS SAGYADGRLF YVDASGALTA
     STLDIAGAKV SGAPQVIAVK VARSPSTYYS SFAIAENSTL VYSADNVTNH SQLTWFDESG
     KETGKGSPVS VLANPALSPD GKWVAYDSND FKAGNVDVWI NDFVRGGSRF TFNPAEEVTP
     IWSRDGSTIA YRTLGNVVPM VQLKKASGLE PEKSLSPLGD ASTDIMANSW SVDGREILCN
     FQTSKGTWEL VVVPVDGGKP RPFLSGLGNK MNGQISPDGK WVAYASNETG DWEIYATTYP
     AAAGKWQVSR GGGSEPRWRG DGKAIFYIGP RQMLTEMVVS TEGTFSTAAV RSLFPVHARP
     PISSTDIVTY DVTRDGKHFL VNQYVRPDQP APLTVVMHAA NALAR
//